YRC Public Data Repository - Protein Structure Prediction

Protein:	UDG_ECOLI
Organism:	Escherichia coli
Length:	388 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UDG_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|83635660, gi\|... - gi\|83647617\|ref\|YP_436052.1\| UDP-glucose 6-dehydrogenase [Hahella chejuensis KCTC 2396], gi\|83635660...	351.0	[0..1]	[388..1]
gi\|77955807, gi\|... - gi\|77955807\|ref\|ZP_00820145.1\| UDP-glucose 6-dehydrogenase [Marinobacter aquaeolei VT8], gi\|77865306...	349.0	[0..1]	[388..1]
gi\|88818028, gi\|... - gi\|88860034\|ref\|ZP_01134673.1\| hypothetical protein PTD2_18520 [Pseudoalteromonas tunicata D2], gi\|8...	347.0	[0..1]	[387..1]
gi\|28172994 - gi\|28172994\|gb\|AAO32664.1\|AF499932_6 nucleotide sugar dehydrogenase [Vibrio vulnificus]	343.0	[0..1]	[388..1]
gi\|89081559, gi\|... - gi\|89094084\|ref\|ZP_01167027.1\| hypothetical protein MED92_16115 [Oceanospirillum sp. MED92], gi\|8908...	343.0	[0..1]	[388..1]
gi\|76590942, gi\|... - gi\|76793760\|ref\|ZP_00776242.1\| UDP-glucose 6-dehydrogenase [Pseudoalteromonas atlantica T6c], gi\|765...	341.0	[0..1]	[388..1]
gi\|84325874, gi\|... - gi\|84325874\|ref\|ZP_00973906.1\| COG1004: Predicted UDP-glucose 6-dehydrogenase [Pseudomonas aeruginos...	341.0	[0..1]	[388..1]
gi\|74316979, gi\|... - gi\|74316979\|ref\|YP_314719.1\| UDP-glucose dehydrogenase [Thiobacillus denitrificans ATCC 25259], gi\|7...	340.0	[0..1]	[387..1]
gi\|11351549 - pir\|\|B83202 probable nucleotide sugar dehydrogenase PA3559 [imported] - Pseudomonas aeruginosa (stra... gi\|9949711, gi\|1... - gi\|9949711\|gb\|AAG06947.1\|AE004776_10 probable nucleotide sugar dehydrogenase [Pseudomonas aeruginosa...	340.0	[0..1]	[388..1]

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Predicted Domain #1

Region A:
Residues: [1-388]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKITISGTGY VGLSNGLLIA QNHEVVALDI LPSRVAMLND RISPIVDKEI QQFLQSDKIH  60
   61 FNATLDKNEA YRDADYVIIA TPTDYDPKTN YFNTSSVESV IKDVVEINPY AVMVIKSTVP 120
  121 VGFTAAMHKK YRTENIIFSP EFLREGKALY DNLHPSRIVI GERSERAERF AALLQEGAIK 180
  181 QNIPMLFTDS TEAEAIKLFA NTYLAMRVAY FNELDSYAES LGLNSRQIIE GVCLDPRIGN 240
  241 HYNNPSFGYG GYCLPKDTKQ LLANYQSVPN NLISAIVDAN RTRKDFIADA ILSRKPQVVG 300
  301 IYRLIMKSGS DNFRASSIQG IMKRIKAKGV EVIIYEPVMK EDSFFNSRLE RDLATFKQQA 360
  361 DVIISNRMAE ELKDVADKVY TRDLFGSD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	72.39794
Match:	1dliA
Description:	UDP-glucose dehydrogenase (UDPGDH), middle domain; UDP-glucose dehydrogenase (UDPGDH); UDP-glucose dehydrogenase (UDPGDH), C-terminal (UDP-binding) domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.16785883389468	bayes_pls_golite062009
oxidoreductase activity	1.95477050413	bayes_pls_golite062009
phosphogluconate dehydrogenase (decarboxylating) activity	0.85002953624923	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	0.771153340292	bayes_pls_golite062009
dTDP-4-dehydrorhamnose reductase activity	0.676398540588099	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	0.66554302844944	bayes_pls_golite062009
fatty acid synthase activity	0.561621495862231	bayes_pls_golite062009
glycerol-3-phosphate dehydrogenase (NAD+) activity	0.323038721318701	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: