YRC Public Data Repository - Protein Structure Prediction

Protein:	UBIX_ECOLI
Organism:	Escherichia coli
Length:	189 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UBIX_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|49612500, gi\|... - gi\|50121974\|ref\|YP_051141.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Pectobacterium atroseptic...	230.0	[0..1]	[189..1]
gi\|37527052, gi\|... - gi\|37527052\|ref\|NP_930396.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Photorhabdus luminescens ...	227.0	[0..1]	[189..1]
gi\|21958397, gi\|... - gi\|22125501\|ref\|NP_668924.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Yersinia pestis KIM], gi\|... gi\|162421715, gi... - gi\|162421715\|ref\|YP_001604962.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Yersinia pestis Angol... gi\|45442180, gi\|... - gi\|45442180\|ref\|NP_993719.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Yersinia pestis biovar Mi...	226.0	[0..1]	[188..6]
gi\|167051306, gi... - gi\|167398802\|ref\|ZP_02304326.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Yersinia pestis biovar... gi\|167421396, gi... - gi\|167421396\|ref\|ZP_02313149.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Yersinia pestis biovar... gi\|167056375, gi... - gi\|167424493\|ref\|ZP_02316246.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Yersinia pestis biovar... gi\|167469033 - gi\|167469033\|ref\|ZP_02333737.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Yersinia pestis FV-1] gi\|170023777, gi... - gi\|170023777\|ref\|YP_001720282.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Yersinia pseudotuberc... gi\|186896011, gi... - gi\|186896011\|ref\|YP_001873123.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Yersinia pseudotuberc... gi\|145210962, gi... - gi\|145599266\|ref\|YP_001163342.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Yersinia pestis Pesto... gi\|149365247, gi... - gi\|149365247\|ref\|ZP_01887282.1\| probable 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Yersinia pest... gi\|25299168 - pir\|\|AE0338 probable 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [imported] - Yersinia pestis (stra... gi\|218929845, gi... - gi\|218929845\|ref\|YP_002347720.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Yersinia pestis CO92]... gi\|51596930, gi\|... - gi\|51596930\|ref\|YP_071121.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Yersinia pseudotuberculos... gi\|165925297, gi... - gi\|165925297\|ref\|ZP_02221129.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Yersinia pestis biovar... gi\|166008113, gi... - gi\|166008113\|ref\|ZP_02229011.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Yersinia pestis biovar... gi\|166204574, gi... - gi\|166214218\|ref\|ZP_02240253.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Yersinia pestis biovar... Q668X6\|Q668X6_YERPS - Probable 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - Yersinia pseudotuberculosis gi\|229680138, gi... - gi\|229902691\|ref\|ZP_04517808.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Yersinia pestis Nepal5... gi\|229688457, gi... - gi\|229898909\|ref\|ZP_04514054.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Yersinia pestis biovar... gi\|77635319 - gi\|77635319\|ref\|ZP_00797405.1\| COG0163: 3-polyprenyl-4-hydroxybenzoate decarboxylase [Yersinia pesti... gi\|229895373, gi... - gi\|229895373\|ref\|ZP_04510546.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Yersinia pestis Pestoi... gi\|153948278, gi... - gi\|77629659\|ref\|ZP_00792245.1\| COG0163: 3-polyprenyl-4-hydroxybenzoate decarboxylase [Yersinia pseud... gi\|89103391, gi\|... - gi\|89103391\|ref\|ZP_01175971.1\| COG0163: 3-polyprenyl-4-hydroxybenzoate decarboxylase [Yersinia pesti... gi\|229694709, gi... - gi\|229838343\|ref\|ZP_04458502.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Yersinia pestis biovar... gi\|108779979, gi... - gi\|108808066\|ref\|YP_651982.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Yersinia pestis Antiqua]...	226.0	[0..1]	[188..1]
gi\|238785199, gi... - gi\|77957375\|ref\|ZP_00821433.1\| COG0163: 3-polyprenyl-4-hydroxybenzoate decarboxylase [Yersinia berco...	224.0	[0..1]	[188..1]
gi\|77960841, gi\|... - gi\|77960841\|ref\|ZP_00824696.1\| COG0163: 3-polyprenyl-4-hydroxybenzoate decarboxylase [Yersinia molla...	223.0	[0..1]	[188..1]
gi\|75177900, gi\|... - gi\|75177900\|ref\|ZP_00697962.1\| COG0163: 3-polyprenyl-4-hydroxybenzoate decarboxylase [Shigella boydi... gi\|191169483, gi... - gi\|75227193\|ref\|ZP_00713997.1\| COG0163: 3-polyprenyl-4-hydroxybenzoate decarboxylase [Escherichia co... gi\|73856305, gi\|... - gi\|74312828\|ref\|YP_311247.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Shigella sonnei Ss046], g... gi\|81246203, gi\|... - gi\|82544792\|ref\|YP_408739.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Shigella boydii Sb227], g... gi\|218554866, gi... - gi\|218554866\|ref\|YP_002387779.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli IAI1...	223.0	[0..1]	[189..1]
gi\|238723276, gi... - gi\|77975504\|ref\|ZP_00831039.1\| COG0163: 3-polyprenyl-4-hydroxybenzoate decarboxylase [Yersinia frede...	222.0	[0..1]	[189..1]
gi\|238795095, gi... - gi\|77976974\|ref\|ZP_00832437.1\| COG0163: 3-polyprenyl-4-hydroxybenzoate decarboxylase [Yersinia inter...	221.0	[0..1]	[189..1]
gi\|226901155, gi... - gi\|237704789\|ref\|ZP_04535270.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia sp. 3_2_53... gi\|117624501, gi... - gi\|117624501\|ref\|YP_853414.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli APEC O1... gi\|91211607, gi\|... - gi\|91211607\|ref\|YP_541593.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli UTI89], ... gi\|110344107, gi... - gi\|110642515\|ref\|YP_670245.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli 536], g... gi\|215265596, gi... - gi\|215487524\|ref\|YP_002329955.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli O127... gi\|75243122, gi\|... - gi\|75243122\|ref\|ZP_00726828.1\| COG0163: 3-polyprenyl-4-hydroxybenzoate decarboxylase [Escherichia co... gi\|218365993, gi... - gi\|218559224\|ref\|YP_002392137.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli S88]... gi\|218428035, gi... - gi\|218690471\|ref\|YP_002398683.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli ED1a...	221.0	[0..1]	[189..1]

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Predicted Domain #1

Region A:
Residues: [1-189]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKRLIVGISG ASGAIYGVRL LQVLRDVTDI ETHLVMSQAA RQTLSLETDF SLREVQALAD  60
   61 VTHDARDIAA SISSGSFQTL GMVILPCSIK TLSGIVHSYT DGLLTRAADV VLKERRPLVL 120
  121 CVRETPLHLG HLRLMTQAAE IGAVIMPPVP AFYHRPQSLD DVINQTVNRV LDQFAITLPE 180
  181 DLFARWQGA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	54.69897
Match:	1sbzA
Description:	Crystal Structure of dodecameric FMN-dependent Ubix-like Decarboxylase from Escherichia coli O157:H7
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity	5.88631349530005	bayes_pls_golite062009
carboxy-lyase activity	2.27469953971238	bayes_pls_golite062009
catalytic activity	1.88716391063227	bayes_pls_golite062009
carbon-carbon lyase activity	1.67751595868044	bayes_pls_golite062009
phosphopantothenoylcysteine decarboxylase activity	1.6488492075417	bayes_pls_golite062009
lyase activity	0.646446561158526	bayes_pls_golite062009
phosphopantothenate--cysteine ligase activity	0.35505046579356	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: