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View Structure Prediction Details

Protein: TOLB_ECOLI
Organism: Escherichia coli
Length: 430 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TOLB_ECOLI.

Description E-value Query
Range
Subject
Range
gi|186464325, gi... - gi|23128981|ref|ZP_00110817.1| COG2319: FOG: WD40 repeat [Nostoc punctiforme PCC 73102], gi|18668187...
391.0 [0..16] [428..1271]
gi|75701503, gi|... - gi|75907778|ref|YP_322074.1| ribosome assembly protein 4 (RSA4) [Anabaena variabilis ATCC 29413], gi...
382.0 [0..16] [428..1143]
gi|37523925, gi|... - gi|37523925|ref|NP_927302.1| WD repeat-containing protein [Gloeobacter violaceus PCC 7421], gi|35214...
374.0 [0..12] [428..664]
gi|17225208 - gi|17225208|gb|AAL37300.1|AF323584_1 beta transducin-like protein HET-E2C*40 [Podospora anserina]
373.0 [0..16] [428..856]
gi|48893630, gi|... - gi|71673807|ref|ZP_00671555.1| TPR repeat:G-protein beta WD-40 repeat:YD repeat [Trichodesmium eryth...
372.0 [0..16] [428..969]

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Predicted Domain #1
Region A:
Residues: [1-430]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKQALRVAFG FLILWASVLH AEVRIVIDSG VDSGRPIGVV PFQWAGPGAA PEDIGGIVAA  60
   61 DLRNSGKFNP LDRARLPQQP GSAQEVQPAA WSALGIDAVV VGQVTPNPDG SYNVAYQLVD 120
  121 TGGAPGTVLA QNSYKVNKQW LRYAGHTASD EVFEKLTGIK GAFRTRIAYV VQTNGGQFPY 180
  181 ELRVSDYDGY NQFVVHRSPQ PLMSPAWSPD GSKLAYVTFE SGRSALVIQT LANGAVRQVA 240
  241 SFPRHNGAPA FSPDGSKLAF ALSKTGSLNL YVMDLASGQI RQVTDGRSNN TEPTWFPDSQ 300
  301 NLAFTSDQAG RPQVYKVNIN GGAPQRITWE GSQNQDADVS SDGKFMVMVS SNGGQQHIAK 360
  361 QDLATGGVQV LSSTFLDETP SLAPNGTMVI YSSSQGMGSV LNLVSTDGRF KARLPATDGQ 420
  421 VKFPAWSPYL 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 87.221849
Match: 1c5kA
Description: TolB, C-terminal domain; TolB, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transporter activity 4.61053807974568 bayes_pls_golite062009
drug transmembrane transporter activity 2.08590634519745 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle