YRC Public Data Repository - Protein Structure Prediction

Protein:	SLYD_ECOLI
Organism:	Escherichia coli
Length:	196 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SLYD_ECOLI.

Description	E-value	Query Range	Subject Range
SLYD_PASMU - FKBP-type peptidyl-prolyl cis-trans isomerase SlyD OS=Pasteurella multocida (strain Pm70) GN=slyD PE... SLYD_PASMU - FKBP-type peptidyl-prolyl cis-trans isomerase slyD OS=Pasteurella multocida GN=slyD PE=1 SV=1	176.0	[0..1]	[193..1]
gi\|117919587, gi... - gi\|78688354\|ref\|ZP_00853054.1\| peptidyl-prolyl cis-trans isomerase SlyD [Shewanella sp. ANA-3], gi\|7...	176.0	[0..1]	[187..1]
gi\|89075234, gi\|... - gi\|89075234\|ref\|ZP_01161665.1\| peptidyl-prolyl cis-trans isomerase [Photobacterium sp. SKA34], gi\|89...	176.0	[0..1]	[196..1]
gi\|227119043, gi... - gi\|75827855\|ref\|ZP_00757290.1\| COG1047: FKBP-type peptidyl-prolyl cis-trans isomerases 2 [Vibrio cho...	175.0	[0..1]	[165..1]
gi\|37199976, gi\|... - gi\|37681225\|ref\|NP_935834.1\| FKBP-type peptidyl-prolyl cis-trans isomerase 2 [Vibrio vulnificus YJ01...	174.0	[0..1]	[154..14]
gi\|116183326, gi... - gi\|75853782\|ref\|ZP_00761545.1\| COG1047: FKBP-type peptidyl-prolyl cis-trans isomerases 2 [Vibrio sp....	173.0	[0..1]	[166..1]
gi\|113888156, gi... - gi\|78690715\|ref\|ZP_00855355.1\| peptidyl-prolyl cis-trans isomerase SlyD [Shewanella sp. MR-7], gi\|78...	173.0	[0..1]	[185..1]
gi\|84509178, gi\|... - gi\|84517060\|ref\|ZP_01004417.1\| peptidyl-prolyl cis-trans isomerase, FKBP-type [Loktanella vestfolden...	172.0	[0..2]	[142..3]
gi\|67519450, gi\|... - gi\|92113423\|ref\|YP_573351.1\| peptidylprolyl isomerase, FKBP-type [Chromohalobacter salexigens DSM 30...	172.0	[0..1]	[161..1]
gi\|82403704, gi\|... - gi\|82498300\|ref\|ZP_00883805.1\| peptidyl-prolyl cis-trans isomerase SlyD [Shewanella sp. MR-4], gi\|82...	172.0	[0..1]	[185..1]

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Predicted Domain #1

Region A:
Residues: [1-196]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVAKDLVVS LAYQVRTEDG VLVDESPVSA PLDYLHGHGS LISGLETALE GHEVGDKFDV  60
   61 AVGANDAYGQ YDENLVQRVP KDVFMGVDEL QVGMRFLAET DQGPVPVEIT AVEDDHVVVD 120
  121 GNHMLAGQNL KFNVEVVAIR EATEEELAHG HVHGAHDHHH DHDHDGCCGG HGHDHGHEHG 180
  181 GEGCCGGKGN GGCGCH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	30.30103
Match:	1ix5A
Description:	Archaeal FKBP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
peptidyl-prolyl cis-trans isomerase activity	4.4182664267098	bayes_pls_golite062009
cis-trans isomerase activity	4.33661522951196	bayes_pls_golite062009
isomerase activity	2.83057106437196	bayes_pls_golite062009
macrolide binding	1.34183721806994	bayes_pls_golite062009
catalytic activity	1.25572252987503	bayes_pls_golite062009
FK506 binding	1.11705415888427	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: