YRC Public Data Repository - Protein Structure Prediction

Protein:	SGBH_ECOLI
Organism:	Escherichia coli
Length:	220 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SGBH_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|59712895, gi\|... - gi\|59712895\|ref\|YP_205671.1\| ribulose-phosphate 3-epimerase [Vibrio fischeri ES114], gi\|59480996\|gb\|...	163.0	[0..1]	[216..1]
gi\|170718563, gi... - gi\|53728308\|ref\|ZP_00348123.1\| COG0036: Pentose-5-phosphate-3-epimerase [Haemophilus somnus 2336], g... gi\|23467805, gi\|... - gi\|23467805\|ref\|ZP_00123383.1\| COG0036: Pentose-5-phosphate-3-epimerase [Haemophilus somnus 129PT], ...	163.0	[0..1]	[215..1]
gi\|153223460, gi... - gi\|153223460\|ref\|ZP_01953883.1\| ribulose-phosphate 3-epimerase [Vibrio cholerae MAK 757], gi\|1241181... gi\|121547642, gi... - gi\|121588099\|ref\|ZP_01677847.1\| ribulose-phosphate 3-epimerase [Vibrio cholerae 2740-80], gi\|1215476... gi\|183179608, gi... - gi\|183179608\|ref\|ZP_02957819.1\| ribulose-phosphate 3-epimerase [Vibrio cholerae MZO-3], gi\|183013019... gi\|125620693, gi... - gi\|254226800\|ref\|ZP_04920373.1\| ribulose-phosphate 3-epimerase [Vibrio cholerae V51], gi\|225354553\|r... gi\|125619178, gi... - gi\|254851164\|ref\|ZP_05240514.1\| ribulose-phosphate 3-epimerase [Vibrio cholerae MO10], gi\|254846869\|... gi\|126520939, gi... - gi\|153821554\|ref\|ZP_01974221.1\| ribulose-phosphate 3-epimerase [Vibrio cholerae B33], gi\|126520939\|g... gi\|153819037, gi... - gi\|153819037\|ref\|ZP_01971704.1\| ribulose-phosphate 3-epimerase [Vibrio cholerae NCTC 8457], gi\|12651... gi\|254285819, gi... - gi\|254285819\|ref\|ZP_04960781.1\| ribulose-phosphate 3-epimerase [Vibrio cholerae AM-19226], gi\|197752... gi\|254222319, gi... - gi\|254222319\|ref\|ZP_04916191.1\| ribulose-phosphate 3-epimerase [Vibrio cholerae RC385], gi\|194536466... gi\|148874448, gi... - gi\|153830049\|ref\|ZP_01982716.1\| ribulose-phosphate 3-epimerase [Vibrio cholerae 623-39], gi\|14887444... gi\|149741243, gi... - gi\|153825097\|ref\|ZP_01977764.1\| ribulose-phosphate 3-epimerase [Vibrio cholerae MZO-2], gi\|149741243... gi\|9657215, gi\|1... - gi\|9657215\|gb\|AAF95766.1\| ribulose-phosphate 3-epimerase [Vibrio cholerae O1 biovar El Tor str. N169... gi\|11270182 - pir\|\|G82052 ribulose-phosphate 3-epimerase VC2625 [imported] - Vibrio cholerae (strain N16961 serogr... gi\|227010629, gi... - gi\|227082741\|ref\|YP_002811292.1\| ribulose-phosphate 3-epimerase [Vibrio cholerae M66-2], gi\|22701062...	162.0	[0..1]	[215..13]
gi\|120326270, gi... - gi\|77953959\|ref\|ZP_00818361.1\| Ribulose-phosphate 3-epimerase [Marinobacter aquaeolei VT8], gi\|77867...	162.0	[0..5]	[215..8]
gi\|63258545, gi\|... - gi\|66047838\|ref\|YP_237679.1\| ribulose-phosphate 3-epimerase [Pseudomonas syringae pv. syringae B728a...	162.0	[0..5]	[216..8]
gi\|86147333, gi\|... - gi\|86147333\|ref\|ZP_01065647.1\| ribulose-phosphate 3-epimerase [Vibrio sp. MED222], gi\|85834898\|gb\|EA...	162.0	[0..1]	[214..1]
gi\|241884589, gi... - gi\|241902997\|ref\|ZP_04787726.1\| Ribulose-phosphate 3-epimerase [Thermoanaerobacter brockii subsp. fi... gi\|166854624, gi... - gi\|167040384\|ref\|YP_001663369.1\| ribulose-phosphate 3-epimerase [Thermoanaerobacter sp. X514], gi\|16... gi\|242231451, gi... - gi\|242257052\|ref\|ZP_04801929.1\| Ribulose-phosphate 3-epimerase [Thermoanaerobacter sp. X513], gi\|242... gi\|166856557, gi... - gi\|76797104\|ref\|ZP_00779444.1\| Ribulose-phosphate 3-epimerase [Thermoanaerobacter ethanolicus ATCC 3...	162.0	[0..1]	[213..1]
gi\|78702071, gi\|... - gi\|78702071\|ref\|ZP_00866514.1\| Ribulose-phosphate 3-epimerase [Alkalilimnicola ehrlichei MLHE-1], gi...	162.0	[0..1]	[214..1]
gi\|84376617, gi\|... - gi\|84390814\|ref\|ZP_00991506.1\| ribulose-phosphate 3-epimerase [Vibrio splendidus 12B01], gi\|84376617...	161.0	[0..1]	[214..1]
gi\|85694283, gi\|... - gi\|85711886\|ref\|ZP_01042941.1\| D-ribulose-5-phosphate 3-epimerase [Idiomarina baltica OS145], gi\|856...	161.0	[0..5]	[213..7]

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Predicted Domain #1

Region A:
Residues: [1-220]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRPLLQLAL DHSSLEAAQR DVTLLKDSVD IVEAGTILCL NEGLGAVKAL REQCPDKIIV  60
   61 ADWKVADAGE TLAQQAFGAG ANWMTIICAA PLATVEKGHA MAQRCGGEIQ IELFGNWTLD 120
  121 DARDWHRIGV RQAIYHRGRD AQASGQQWGE ADLARMKALS DIGLELSITG GITPADLPLF 180
  181 KDIRVKAFIA GRALAGAANP AQVAGDFHAQ IDAIWGGARA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	26.69897
Match:	1kv8A
Description:	3-keto-L-gulonate 6-phosphate decarboxylase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.81275055404078	bayes_pls_golite062009
ribulose-phosphate 3-epimerase activity	1.78763982783413	bayes_pls_golite062009
isomerase activity	1.44927116617243	bayes_pls_golite062009
racemase and epimerase activity, acting on carbohydrates and derivatives	1.29925951177863	bayes_pls_golite062009
3-dehydro-L-gulonate-6-phosphate decarboxylase activity	1.0760062330129	bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting aldoses and ketoses	1.03329951829062	bayes_pls_golite062009
racemase and epimerase activity	1.00826330858943	bayes_pls_golite062009
lyase activity	0.9228652996943	bayes_pls_golite062009
intramolecular oxidoreductase activity	0.55861880143385	bayes_pls_golite062009
carbon-carbon lyase activity	0.1981583216852	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: