YRC Public Data Repository - Protein Structure Prediction

Protein:	RTCA_ECOLI
Organism:	Escherichia coli
Length:	338 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RTCA_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|75516113 - gi\|75516113\|ref\|ZP_00738231.1\| COG0430: RNA 3'-terminal phosphate cyclase [Escherichia coli 53638]	424.0	[0..1]	[338..2]
gi\|91212894, gi\|... - gi\|91212894\|ref\|YP_542880.1\| RNA 3'-terminal-phosphate cyclase [Escherichia coli UTI89], gi\|91074468... gi\|226902415, gi... - gi\|237703151\|ref\|ZP_04533632.1\| RNA 3'-terminal-phosphate cyclase [Escherichia sp. 3_2_53FAA], gi\|22... gi\|115514808, gi... - gi\|117625684\|ref\|YP_859007.1\| RNA 3'-terminal-phosphate cyclase [Escherichia coli APEC O1], gi\|11551...	422.0	[0..1]	[338..2]
gi\|26110450, gi\|... - gi\|26250021\|ref\|NP_756061.1\| RNA 3'-terminal-phosphate cyclase [Escherichia coli CFT073], gi\|2611045...	420.0	[0..1]	[338..2]
RTCA_ECOL5 - RNA 3'-terminal phosphate cyclase OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=rtcA PE=3 SV...	420.0	[0..1]	[338..1]
RTCA_ECOL6 - RNA 3'-terminal phosphate cyclase OS=Escherichia coli O6 GN=rtcA PE=3 SV=2 RTCA_ECOL6 - RNA 3'-terminal phosphate cyclase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=...	420.0	[0..1]	[338..1]
gi\|75179961 - gi\|75179961\|ref\|ZP_00699948.1\| COG0430: RNA 3'-terminal phosphate cyclase [Shigella boydii BS512]	419.0	[0..1]	[338..2]
gi\|81247187, gi\|... - gi\|82545776\|ref\|YP_409723.1\| RNA 3'-terminal-phosphate cyclase [Shigella boydii Sb227], gi\|81247187\|...	419.0	[0..1]	[338..2]
gi\|75197350 - gi\|75197350\|ref\|ZP_00707420.1\| COG0430: RNA 3'-terminal phosphate cyclase [Escherichia coli HS] gi\|83588716 - gi\|83588716\|ref\|ZP_00927340.1\| COG0430: RNA 3'-terminal phosphate cyclase [Escherichia coli 101-1]	418.0	[0..4]	[338..1]
gi\|6980698, gi\|6... - gi\|6980698\|pdb\|1QMH\|B Chain B, Crystal Structure Of Rna 3'-Terminal Phosphate Cyclase, An Ubiquitous...	418.0	[0..1]	[338..2]
gi\|75211786 - gi\|75211786\|ref\|ZP_00711850.1\| COG0430: RNA 3'-terminal phosphate cyclase [Escherichia coli B171]	417.0	[0..1]	[338..2]

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Predicted Domain #1

Region A:
Residues: [1-338]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKRMIALDGA QGEGGGQILR SALSLSMITG QPFTITSIRA GRAKPGLLRQ HLTAVKAATE  60
   61 ICGATVEGAE LGSQRLLFRP GTVRGGDYRF AIGSAGSCTL VLQTVLPALW FADGPSRVEV 120
  121 SGGTDNPSAP PADFIRRVLE PLLAKIGIHQ QTTLLRHGFY PAGGGVVATE VSPVASFNTL 180
  181 QLGERGNIVQ MRGEVLLAGV PRHVAEREIA TLAGSFSLHE QNIHNLPRDQ GPGNTVSLEV 240
  241 ESENITERFF VVGEKRVSAE VVAAQLVKEV KRYLASTAAV GEYLADQLVL PMALAGAGEF 300
  301 TVAHPSCHLL TNIAVVERFL PVRFSLIETD GVTRVSIE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	117.0
Match:	1qmhA
Description:	RNA 3'-terminal phosphate cyclase, RPTC, insert domain; RNA 3'-terminal phosphate cyclase, RPTC
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.54689525592227	bayes_pls_golite062009
transferase activity	1.7007536630883	bayes_pls_golite062009
transferase activity, transferring alkyl or aryl (other than methyl) groups	1.24131488513793	bayes_pls_golite062009
UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity	0.249795968966795	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: