YRC Public Data Repository - Protein Structure Prediction

Protein:	RPIB_ECOLI
Organism:	Escherichia coli
Length:	149 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RPIB_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|110683235, gi... - gi\|110802734\|ref\|YP_699473.1\| ribose-5-phosphate isomerase B [Clostridium perfringens SM101], gi\|110... gi\|18145863, gi\|... - gi\|18311180\|ref\|NP_563114.1\| ribose-5-phosphate isomerase B [Clostridium perfringens str. 13], gi\|18... gi\|110800386, gi... - gi\|110800386\|ref\|YP_696877.1\| ribose-5-phosphate isomerase B [Clostridium perfringens ATCC 13124], g... gi\|170711788, gi... - gi\|170711788\|gb\|EDT23970.1\| ribose 5-phosphate isomerase B [Clostridium perfringens B str. ATCC 3626... gi\|168213698, gi... - gi\|170714766\|gb\|EDT26948.1\| ribose 5-phosphate isomerase B [Clostridium perfringens CPE str. F4969],... gi\|168215827, gi... - gi\|182382193\|gb\|EDT79672.1\| ribose 5-phosphate isomerase B [Clostridium perfringens NCTC 8239], gi\|1...	239.0	[0..2]	[148..1]
gi\|25309787 - pir\|\|D97254 ribose 5-phosphate isomerase, RpiB [imported] - Clostridium acetobutylicum gi\|15896134, gi\|... - gi\|15896134\|ref\|NP_349483.1\| ribose-5-phosphate isomerase B [Clostridium acetobutylicum ATCC 824], g...	232.0	[0..2]	[149..1]
gi\|20806675 - gi\|20806675\|ref\|NP_621846.1\| Ribose 5-phosphate isomerase RpiB [Thermoanaerobacter tengcongensis MB4... gi\|20806675, gi\|... - gi\|20806675\|ref\|NP_621846.1\| ribose 5-phosphate isomerase RpiB [Thermoanaerobacter tengcongensis MB4...	231.0	[0..4]	[148..156]
gi\|78043323, gi\|... - gi\|78043323\|ref\|YP_361351.1\| ribose-5-phosphate isomerase B [Carboxydothermus hydrogenoformans Z-290...	230.0	[0..2]	[148..1]
gi\|67873844, gi\|... - gi\|67873844\|ref\|ZP_00503831.1\| Ribose/galactose isomerase [Clostridium thermocellum ATCC 27405], gi\|... gi\|196251796, gi... - gi\|196251796\|ref\|ZP_03150462.1\| sugar-phosphate isomerase, RpiB/LacA/LacB family [Clostridium thermo...	229.0	[0..2]	[148..1]
gi\|89210215, gi\|... - gi\|89210215\|ref\|ZP_01188607.1\| Ribose/galactose isomerase:Ribose 5-phosphate isomerase B [Halothermo...	227.0	[0..2]	[146..175]
gi\|83591208, gi\|... - gi\|83591208\|ref\|YP_431217.1\| ribose-5-phosphate isomerase [Moorella thermoacetica ATCC 39073], gi\|83...	226.0	[0..3]	[148..20]
gi\|34810962, gi\|... - gi\|34810964\|pdb\|1NN4\|D Chain D, Structural Genomics, RpibALSB, gi\|34810963\|pdb\|1NN4\|C Chain C, Struc...	225.0	[0..1]	[149..14]
gi\|106895273, gi... - gi\|158321593\|ref\|YP_001514100.1\| RpiB/LacA/LacB family sugar-phosphate isomerase [Alkaliphilus oreml...	225.0	[0..2]	[148..1]
gi\|26250907, gi\|... - gi\|26250907\|ref\|NP_756947.1\| ribose-5-phosphate isomerase B [Escherichia coli CFT073], gi\|26111339\|g... gi\|227836213, gi... - gi\|227886871\|ref\|ZP_04004676.1\| ribose-5-phosphate isomerase B [Escherichia coli 83972], gi\|22783621...	223.0	[0..1]	[149..1]

Back

Predicted Domain #1

Region A:
Residues: [1-149]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKIAFGCDH VGFILKHEIV AHLVERGVEV IDKGTWSSER TDYPHYASQV ALAVAGGEVD  60
   61 GGILICGTGV GISIAANKFA GIRAVVCSEP YSAQLSRQHN DTNVLAFGSR VVGLELAKMI 120
  121 VDAWLGAQYE GGRHQQRVEA ITAIEQRRN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	59.39794
Match:	1nn4A
Description:	Alternate ribose 5-phosphate isomerase B, RpiB
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ribose-5-phosphate isomerase activity	5.69997185547565	bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting aldoses and ketoses	4.04314332668154	bayes_pls_golite062009
intramolecular oxidoreductase activity	3.57097659815257	bayes_pls_golite062009
isomerase activity	2.42530141345385	bayes_pls_golite062009
catalytic activity	2.21687627610124	bayes_pls_golite062009
allose 6-phosphate isomerase activity	2.20293230847792	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: