YRC Public Data Repository - Protein Structure Prediction

Protein:	RHSC_ECOLI
Organism:	Escherichia coli
Length:	1397 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RHSC_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|25308817 - pir\|\|A85570 rhsC protein in rhs element, interrupted [imported] - Escherichia coli (strain O157:H7, ... gi\|12513606, gi\|... - gi\|15800401\|ref\|NP_286413.1\| rhsC protein in rhs element, interrupted [Escherichia coli O157:H7 EDL9...	1058.0	[0..1]	[1397..1]
gi\|75194863, gi\|... - gi\|75194863\|ref\|ZP_00704933.1\| COG3209: Rhs family protein [Escherichia coli HS], gi\|157160181\|ref\|Y...	1054.0	[0..1]	[1397..1]
gi\|157155232, gi... - gi\|75189725\|ref\|ZP_00702992.1\| COG3209: Rhs family protein [Escherichia coli E24377A], gi\|157155232\|...	1048.0	[0..1]	[1397..1]
gi\|75256413, gi\|... - gi\|75256413\|ref\|ZP_00728071.1\| COG3209: Rhs family protein [Escherichia coli E22], gi\|193065551\|ref\|...	1046.0	[0..1]	[1397..1]
gi\|25308809, gi\|... - pir\|\|F91187 rhsA core protein with extension [imported] - Escherichia coli (strain O157:H7, substrai... gi\|15833724, gi\|... - gi\|15833724\|ref\|NP_312497.1\| rhsA core protein with extension [Escherichia coli O157:H7 str. Sakai],... gi\|15833724, gi\|... - gi\|15833724\|ref\|NP_312497.1\| rhsA core protein with extension [Escherichia coli O157:H7], gi\|1336394... gi\|217325730, gi... - gi\|217325730\|ref\|ZP_03441814.1\| Rhs family protein [Escherichia coli O157:H7 str. TW14588], gi\|21732... gi\|189369535, gi... - gi\|189369535\|gb\|EDU87951.1\| Rhs family protein [Escherichia coli O157:H7 str. EC4501], gi\|168759684\|...	879.0	[0..1]	[1312..1]
gi\|81244544, gi\|... - gi\|82543133\|ref\|YP_407080.1\| rhsC protein in rhs element [Shigella boydii Sb227], gi\|81244544\|gb\|ABB...	875.0	[0..1]	[1249..1]
gi\|75234516, gi\|... - gi\|75234516\|ref\|ZP_00718863.1\| COG3209: Rhs family protein [Escherichia coli E110019], gi\|193070642\|...	871.0	[0..1]	[1275..1]
gi\|170082996, gi... - gi\|170082996\|ref\|YP_001732316.1\| rhsB element core protein RshB [Escherichia coli str. K-12 substr. ... gi\|89110530, gi\|... - gi\|89110530\|ref\|AP_004310.1\| rhsB element core protein RshB [Escherichia coli str. K-12 substr. W311... EG10847 - Rhs protein with DUF4329 family putative toxin domain; putative neighboring cell growth inhibitor / ... gi\|238902573, gi... - gi\|238902573\|ref\|YP_002928369.1\| rhsB element core protein RshB [Escherichia coli BW2952], gi\|238863... RHSB_ECOLI - Protein rhsB precursor - Escherichia coli EG10847 - Rhs protein with DUF4329 family putative toxin domain; putative neighboring cell growth inhibitor / ...	871.0	[0..1]	[1284..1]
gi\|194414428, gi... - gi\|75211350\|ref\|ZP_00711449.1\| COG3209: Rhs family protein [Escherichia coli B171], gi\|194427388\|ref...	871.0	[0..1]	[1284..1]

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Predicted Domain #1

Region A:
Residues: [1-269]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGKPAARQG DMTQYGGSIV QGSAGVRIGA PTGVACSVCP GGVTSGHPVN PLLGAKVLPG  60
   61 ETDIALPGPL PFILSRTYSS YRTKTPAPVG SLGPGWKMPA DIRLQLRDNT LILSDNGGRS 120
  121 LYFEHLFPGE DGYSRSESLW LVRGGVAKLD EGHRLAALWQ ALPEELRLSP HRYLATNSPQ 180
  181 GPWWLLGWCE RVPEADEVLP APLPPYRVLT GLVDRFGRTQ TFHREAAGEF SGEITGVTDG 240
  241 AGRHFRLVLT TQAQRAEEAR QQAISGGTE

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.87
Match:	2fkgA
Description:	No description for 2fkgA was found.

Predicted Domain #2

Region A:
Residues: [270-373]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSAFPDTLPG YTEYGRDNGI RLSAVWLTHD PEYPENLPAA PLVRYGWTPR GELAAVYDRS  60
   61 NTQVRSFTYD DKYRGRMVAH RHTGRPEICY RYDSDGRVTE QLNP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	11.522879
Match:	1pguA
Description:	Actin interacting protein 1
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [374-915]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AGLSYTYQYE KDRITITDSL NRREVLHTQG EGGLKRVVKK EHADGSVTQS QFDAVGRLRA  60
   61 QTDAAGRTTE YSPDVVTGLI TRITTPDGRA SAFYYNHHSQ LTSATGPDGL EIRREYDEWG 120
  121 RLIQETAPDG DITRYRYDNP HSDLPCATED ATGSRKTMTW SRYGQLLSFT DCSGYVTRYD 180
  181 HDRFGQVTAV HREEGLSQYR AYDSRGQLIA VKDTQGHETR YEYNAAGDLT TVIAPDGSRN 240
  241 GTQYDAWGKA ICTTQGGLTR SMEYDAAGRV IRLTSENGSH TTFRYDVLDR LIQETGFDGR 300
  301 TQRYHHDLTG KLIRSEDEGL VTHWHYDEAD RLTHRTVNGE TAERWQYDER GWLTDISHIS 360
  361 EGHRVTVHYG YDSKGRLASE HLTVHHPQTN ELLWQHETRH AYNAQGLANR CIPDSLPAVE 420
  421 WLTYGSGWLS GMKLGDTPLV EYTRDRLHRE TLRSFGRYEL TTAYTPAGQL QSQHLNSLLS 480
  481 DRDYTWNDNG ELIRISSPRQ TRSYSYSTTG RLTGVHTTAA NLDIRIPYTT DPAGNRLPDP 540
  541 EL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	28.522879
Match:	1nr0A
Description:	Actin interacting protein 1
Matching Structure (courtesy of the PDB):

Predicted Domain #4

Region A:
Residues: [916-1249]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HPDSALSMWP DNRIARDAHY LYRYDRHGRL TEKTDLIPEG VIRTDDERTH RYHYDSQHRL  60
   61 VHYTRTQYAE PLVESRYLYD PLGRRVAKRV WRRERDLTGW MSLSRKPQVT WYGWDGDRLT 120
  121 TIQNDRTRIQ TIYQPGSFTP LIRVETATGE LAKTQRRSLA DTLQQSGGED GGSVVFPPVL 180
  181 VQMLDRLESE ILADRVSEES RRWLASCGLT VAQMQSQMDP VYTPARKIHL YHCDHRGLPL 240
  241 ALISTEGTTA WYAEYDEWGN LLNEENPHQL QQLIRLPGQQ YDEESGLYYN RHRYYDPLQG 300
  301 RYITQDPIGL KGGWNFYQYP LNPISNIDPL GLET

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	2.56
Match:	2fkjA
Description:	No description for 2fkjA was found.

Predicted Domain #5

Region A:
Residues: [1250-1397]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LKCIKPLHSM GGTGERSGPD IWGNPFYHQY LCVPDGKGDY TCGGQDQRGE SKGDGLWGPG  60
   61 KASNDTKEAA GRCDLVETDN SCVENCLKGK FKEVRPRYSV LPDIFTPINL GLFKNCQDWS 120
  121 NDSLETCKMK CSGNNIGRFI RFVFTGVM

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits