YRC Public Data Repository - Protein Structure Prediction

Protein:	PRMA_ECOLI
Organism:	Escherichia coli
Length:	293 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PRMA_ECOLI.

Description	E-value	Query Range	Subject Range
PRMA_PASMU - Ribosomal protein L11 methyltransferase OS=Pasteurella multocida GN=prmA PE=3 SV=1 PRMA_PASMU - Ribosomal protein L11 methyltransferase OS=Pasteurella multocida (strain Pm70) GN=prmA PE=3 SV=1	261.0	[0..1]	[291..1]
PRMA_HAEI8 - Ribosomal protein L11 methyltransferase OS=Haemophilus influenzae (strain 86-028NP) GN=prmA PE=3 SV=...	260.0	[0..1]	[290..1]
gi\|145634154, gi... - gi\|145634154\|ref\|ZP_01789865.1\| ribosomal protein L11 methyltransferase [Haemophilus influenzae Pitt... gi\|145632363, gi... - gi\|145632363\|ref\|ZP_01788098.1\| ribosomal protein L11 methyltransferase [Haemophilus influenzae 3655... gi\|145630071 - gi\|145630071\|ref\|ZP_01785853.1\| ribosomal protein L11 methyltransferase [Haemophilus influenzae 22.4... gi\|229843963, gi... - gi\|229843963\|ref\|ZP_04464104.1\| ribosomal protein L11 methyltransferase [Haemophilus influenzae 6P18... gi\|145628085, gi... - gi\|145628085\|ref\|ZP_01783886.1\| ribosomal protein L11 methyltransferase [Haemophilus influenzae 22.1... gi\|46129085 - gi\|46129085\|ref\|ZP_00155730.2\| COG2264: Ribosomal protein L11 methylase [Haemophilus influenzae R284... gi\|229846036, gi... - gi\|229846036\|ref\|ZP_04466148.1\| ribosomal protein L11 methyltransferase [Haemophilus influenzae 7P49... gi\|42631299 - gi\|42631299\|ref\|ZP_00156837.1\| COG2264: Ribosomal protein L11 methylase [Haemophilus influenzae R286... gi\|144984352 - gi\|144984352\|gb\|EDJ91775.1\| ribosomal protein L11 methyltransferase [Haemophilus influenzae R3021] PRMA_HAEIG - Ribosomal protein L11 methyltransferase OS=Haemophilus influenzae (strain PittGG) GN=prmA PE=3 SV=1 PRMA_HAEIE - Ribosomal protein L11 methyltransferase OS=Haemophilus influenzae (strain PittEE) GN=prmA PE=3 SV=1 gi\|145638200, gi... - gi\|145638200\|ref\|ZP_01793810.1\| ribosomal protein L11 methyltransferase [Haemophilus influenzae Pitt...	259.0	[0..1]	[291..1]
PRMA_ACTSZ - Ribosomal protein L11 methyltransferase OS=Actinobacillus succinogenes (strain ATCC 55618 / 130Z) GN...	259.0	[0..1]	[291..1]
PRMA_HISS2 - Ribosomal protein L11 methyltransferase OS=Histophilus somni (strain 2336) GN=prmA PE=3 SV=1	258.0	[0..1]	[293..1]
PRMA_HAES1 - Ribosomal protein L11 methyltransferase OS=Haemophilus somnus (strain 129Pt) GN=prmA PE=3 SV=1	256.0	[0..1]	[293..1]
PRMA_HAEDU - Ribosomal protein L11 methyltransferase OS=Haemophilus ducreyi GN=prmA PE=3 SV=1 PRMA_HAEDU - Ribosomal protein L11 methyltransferase OS=Haemophilus ducreyi (strain 35000HP / ATCC 700724) GN=prm...	255.0	[0..1]	[292..1]
PRMA_HAEIN - Ribosomal protein L11 methyltransferase OS=Haemophilus influenzae GN=prmA PE=3 SV=1 PRMA_HAEIN - Ribosomal protein L11 methyltransferase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / K...	252.0	[0..1]	[291..1]
PRMA_ERWCT - Ribosomal protein L11 methyltransferase OS=Erwinia carotovora subsp. atroseptica GN=prmA PE=3 SV=1 PRMA_PECAS - Ribosomal protein L11 methyltransferase OS=Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-...	251.0	[0..1]	[293..1]
PRMA_VIBC3 - Ribosomal protein L11 methyltransferase OS=Vibrio cholerae serotype O1 (strain ATCC 39541 / Classica...	251.0	[0..1]	[292..1]

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Predicted Domain #1

Region A:
Residues: [1-293]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPWIQLKLNT TGANAEDLSD ALMEAGAVSI TFQDTHDTPV FEPLPGETRL WGDTDVIGLF  60
   61 DAETDMNDVV AILENHPLLG AGFAHKIEQL EDKDWEREWM DNFHPMRFGE RLWICPSWRD 120
  121 VPDENAVNVM LDPGLAFGTG THPTTSLCLQ WLDSLDLTGK TVIDFGCGSG ILAIAALKLG 180
  181 AAKAIGIDID PQAIQASRDN AERNGVSDRL ELYLPKDQPE EMKADVVVAN ILAGPLRELA 240
  241 PLISVLPVSG GLLGLSGILA SQAESVCEAY ADSFALDPVV EKEEWCRITG RKN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	30.0
Match:	1ufkA
Description:	Crystal structure of TT0836
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
S-adenosylmethionine-dependent methyltransferase activity	4.81722723955895	bayes_pls_golite062009
methyltransferase activity	4.64500705012502	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	4.57389022626587	bayes_pls_golite062009
protein methyltransferase activity	3.85056781737182	bayes_pls_golite062009
N-methyltransferase activity	3.00112136063228	bayes_pls_golite062009
rRNA methyltransferase activity	2.44443043670156	bayes_pls_golite062009
transferase activity	2.42370637689376	bayes_pls_golite062009
histone methyltransferase activity	2.40337598041915	bayes_pls_golite062009
arginine N-methyltransferase activity	2.25021293330454	bayes_pls_golite062009
protein-arginine N-methyltransferase activity	2.25021293330454	bayes_pls_golite062009
DNA-methyltransferase activity	1.8182614465692	bayes_pls_golite062009
catalytic activity	1.62377578202456	bayes_pls_golite062009
histone-arginine N-methyltransferase activity	1.49701653866454	bayes_pls_golite062009
RNA methyltransferase activity	1.36067005317038	bayes_pls_golite062009
protein-arginine omega-N monomethyltransferase activity	1.16693241506234	bayes_pls_golite062009
site-specific DNA-methyltransferase (adenine-specific) activity	0.88654745691593	bayes_pls_golite062009
protein-arginine omega-N asymmetric methyltransferase activity	0.70686255278148	bayes_pls_golite062009
histone methyltransferase activity (H4-R3 specific)	0.64299622477655	bayes_pls_golite062009
rRNA (adenine) methyltransferase activity	0.42556595268413	bayes_pls_golite062009
O-methyltransferase activity	0.32686871890222	bayes_pls_golite062009
rRNA (adenine-N6,N6-)-dimethyltransferase activity	0.32546946538886	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: