YRC Public Data Repository - Protein Structure Prediction

Protein:	PPA_ECOLI
Organism:	Escherichia coli
Length:	432 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PPA_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|110342761, gi... - gi\|110641169\|ref\|YP_668899.1\| phosphoanhydride phosphorylase [Escherichia coli 536], gi\|110342761\|gb...	339.0	[0..1]	[432..11]
gi\|75240597, gi\|... - gi\|75240597\|ref\|ZP_00724514.1\| hypothetical protein EcolF_01002315 [Escherichia coli F11], gi\|191172...	339.0	[0..1]	[432..1]
gi\|26107406, gi\|... - gi\|26247006\|ref\|NP_753046.1\| phosphoanhydride phosphorylase [Escherichia coli CFT073], gi\|26107406\|g...	337.0	[0..1]	[432..11]
gi\|194429835, gi... - gi\|75208934\|ref\|ZP_00709207.1\| hypothetical protein EcolB_01003877 [Escherichia coli B171], gi\|19442...	336.0	[0..1]	[432..1]
gi\|75230254, gi\|... - gi\|75230254\|ref\|ZP_00716751.1\| hypothetical protein EcolB7_01001514 [Escherichia coli B7A], gi\|19116... gi\|157081153, gi... - gi\|75190047\|ref\|ZP_00703314.1\| hypothetical protein EcolE_01003341 [Escherichia coli E24377A], gi\|15... gi\|194438014, gi... - gi\|83586473\|ref\|ZP_00925107.1\| hypothetical protein Ecol1_01002367 [Escherichia coli 101-1], gi\|1944... gi\|253325034, gi... - gi\|254287901\|ref\|YP_003053649.1\| phosphoanhydride phosphorylase [Escherichia coli BL21(DE3)], gi\|253... gi\|242376794, gi... - gi\|251784521\|ref\|YP_002998825.1\| hypothetical protein B21_00990 [Escherichia coli BL21], gi\|24237679... gi\|218351245, gi... - gi\|218694513\|ref\|YP_002402180.1\| phosphoanhydride phosphorylase [Escherichia coli 55989], gi\|2183512... gi\|253972994, gi... - gi\|254161093\|ref\|YP_003044201.1\| phosphoanhydride phosphorylase [Escherichia coli B str. REL606], gi...	335.0	[0..1]	[432..1]
gi\|75255600 - gi\|75255600\|ref\|ZP_00727384.1\| hypothetical protein EcolE2_01004367 [Escherichia coli E22]	334.0	[0..1]	[432..1]
gi\|193070045, gi... - gi\|75235136\|ref\|ZP_00719378.1\| hypothetical protein EcolE1_01002997 [Escherichia coli E110019], gi\|1...	334.0	[0..1]	[432..1]
gi\|56383338, gi\|... - gi\|56479787\|ref\|NP_706903.2\| phosphoanhydride phosphorylase [Shigella flexneri 2a str. 301], gi\|5638...	333.0	[0..1]	[432..1]
gi\|91210078, gi\|... - gi\|91210078\|ref\|YP_540064.1\| phosphoanhydride phosphorylase [Escherichia coli UTI89], gi\|91071652\|gb... gi\|117623189, gi... - gi\|117623189\|ref\|YP_852102.1\| phosphoanhydride phosphorylase [Escherichia coli APEC O1], gi\|11551231... gi\|226898244, gi... - gi\|237707034\|ref\|ZP_04537515.1\| phosphoanhydride phosphorylase [Escherichia sp. 3_2_53FAA], gi\|22689...	333.0	[0..1]	[432..11]
gi\|30040764, gi\|... - gi\|30062518\|ref\|NP_836689.1\| phosphoanhydride phosphorylase [Shigella flexneri 2a str. 2457T], gi\|30...	333.0	[0..1]	[432..1]

Back

Predicted Domain #1

Region A:
Residues: [1-432]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKAILIPFLS LLIPLTPQSA FAQSEPELKL ESVVIVSRHG VRAPTKATQL MQDVTPDAWP  60
   61 TWPVKLGWLT PRGGELIAYL GHYQRQRLVA DGLLAKKGCP QSGQVAIIAD VDERTRKTGE 120
  121 AFAAGLAPDC AITVHTQADT SSPDPLFNPL KTGVCQLDNA NVTDAILSRA GGSIADFTGH 180
  181 RQTAFRELER VLNFPQSNLC LKREKQDESC SLTQALPSEL KVSADNVSLT GAVSLASMLT 240
  241 EIFLLQQAQG MPEPGWGRIT DSHQWNTLLS LHNAQFYLLQ RTPEVARSRA TPLLDLIKTA 300
  301 LTPHPPQKQA YGVTLPTSVL FIAGHDTNLA NLGGALELNW TLPGQPDNTP PGGELVFERW 360
  361 RRLSDNSQWI QVSLVFQTLQ QMRDKTPLSL NTPPGEVKLT LAGCEERNAQ GMCSLAGFTQ 420
  421 IVNEARIPAC SL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	84.522879
Match:	1dkmA
Description:	Phytase (myo-inositol-hexakisphosphate-3-phosphohydrolase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.84708627579827	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: