YRC Public Data Repository - Protein Structure Prediction

Protein:	PHP_ECOLI
Organism:	Escherichia coli
Length:	292 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PHP_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|89084133, gi\|... - gi\|89101165\|ref\|ZP_01173998.1\| YabD [Bacillus sp. NRRL B-14911], gi\|89084133\|gb\|EAR63301.1\| YabD [Ba...	242.0	[0..9]	[291..1]
gi\|91201025 - gi\|91201025\|emb\|CAJ74083.1\| conserved hypothetical protein [Candidatus Kuenenia stuttgartiensis]	241.0	[0..8]	[291..15]
gi\|95133324, gi\|... - gi\|95930672\|ref\|ZP_01313406.1\| TatD-related deoxyribonuclease [Desulfuromonas acetoxidans DSM 684], ...	240.0	[0..10]	[291..6]
gi\|52078534, gi\|... - gi\|52783896\|ref\|YP_089725.1\| YabD [Bacillus licheniformis ATCC 14580], gi\|52346398\|gb\|AAU39032.1\| Ya...	240.0	[0..9]	[291..1]
gi\|77545376, gi\|... - gi\|77919293\|ref\|YP_357108.1\| Mg-dependent DNase [Pelobacter carbinolicus DSM 2380], gi\|77545376\|gb\|A...	239.0	[0..9]	[291..7]
gi\|90579077, gi\|... - gi\|90579077\|ref\|ZP_01234887.1\| putative deoxyribonuclease [Vibrio angustum S14], gi\|90439910\|gb\|EAS6...	238.0	[0..9]	[291..1]
gi\|27352778, gi\|... - gi\|27379626\|ref\|NP_771155.1\| hypothetical protein bll4515 [Bradyrhizobium japonicum USDA 110], gi\|27...	238.0	[0..9]	[291..1]
gi\|71847437, gi\|... - gi\|71907816\|ref\|YP_285403.1\| TatD-related deoxyribonuclease [Dechloromonas aromatica RCB], gi\|718474...	237.0	[0..9]	[292..1]
gi\|170707566, gi... - gi\|170707566\|ref\|ZP_02898019.1\| deoxyribonuclease, TatD family [Bacillus anthracis str. A0389], gi\|1... gi\|177655347, gi... - gi\|177655347\|ref\|ZP_02936876.1\| deoxyribonuclease, TatD family [Bacillus anthracis str. A0174], gi\|1... gi\|190568989, gi... - gi\|190568989\|ref\|ZP_03021890.1\| deoxyribonuclease, TatD family [Bacillus anthracis Tsiankovskii-I], ... gi\|196036356, gi... - gi\|196036356\|ref\|ZP_03103753.1\| deoxyribonuclease, TatD family [Bacillus cereus W], gi\|195990986\|gb\|... gi\|196027406, gi... - gi\|196041786\|ref\|ZP_03109076.1\| deoxyribonuclease, TatD family [Bacillus cereus NVH0597-99], gi\|1960... gi\|218535153, gi... - gi\|218901240\|ref\|YP_002449074.1\| deoxyribonuclease, TatD family [Bacillus cereus AH820], gi\|21853515... gi\|164711717, gi... - gi\|165872589\|ref\|ZP_02217221.1\| deoxyribonuclease, TatD family [Bacillus anthracis str. A0488], gi\|1... gi\|167635090, gi... - gi\|167635090\|ref\|ZP_02393407.1\| deoxyribonuclease, TatD family [Bacillus anthracis str. A0442], gi\|1... gi\|167510519, gi... - gi\|167641534\|ref\|ZP_02399782.1\| deoxyribonuclease, TatD family [Bacillus anthracis str. A0193], gi\|1... gi\|170667141, gi... - gi\|170688917\|ref\|ZP_02880119.1\| deoxyribonuclease, TatD family [Bacillus anthracis str. A0465], gi\|1... gi\|254762418 - gi\|254762418\|ref\|ZP_05214260.1\| deoxyribonuclease, TatD family protein [Bacillus anthracis str. Aust... gi\|254756362 - gi\|254756362\|ref\|ZP_05208391.1\| deoxyribonuclease, TatD family protein [Bacillus anthracis str. Voll... gi\|254744657 - gi\|254744657\|ref\|ZP_05202336.1\| deoxyribonuclease, TatD family protein [Bacillus anthracis str. Krug... gi\|254733575 - gi\|254733575\|ref\|ZP_05191296.1\| deoxyribonuclease, TatD family protein [Bacillus anthracis str. West... gi\|254682334 - gi\|254682334\|ref\|ZP_05146195.1\| deoxyribonuclease, TatD family protein [Bacillus anthracis str. CNEV... gi\|229604431, gi... - gi\|229604431\|ref\|YP_002864690.1\| deoxyribonuclease, TatD family [Bacillus anthracis str. A0248], gi\|... gi\|229119702, gi... - gi\|229119702\|ref\|ZP_04248964.1\| Uncharacterized deoxyribonuclease yabD [Bacillus cereus 95/8201], gi... gi\|49477127, gi\|... - gi\|49477127\|ref\|YP_034393.1\| TatD related DNase [Bacillus thuringiensis serovar konkukian str. 97-27... gi\|229089171, gi... - gi\|229089171\|ref\|ZP_04220453.1\| Uncharacterized deoxyribonuclease yabD [Bacillus cereus Rock3-42], g... gi\|228815803, gi... - gi\|228943846\|ref\|ZP_04106232.1\| Uncharacterized deoxyribonuclease yabD [Bacillus thuringiensis serov... gi\|228828094, gi... - gi\|228931542\|ref\|ZP_04094449.1\| Uncharacterized deoxyribonuclease yabD [Bacillus thuringiensis serov... gi\|228912779, gi... - gi\|228912779\|ref\|ZP_04076427.1\| Uncharacterized deoxyribonuclease yabD [Bacillus thuringiensis serov... gi\|227002938, gi... - gi\|227812712\|ref\|YP_002812721.1\| deoxyribonuclease, TatD family [Bacillus anthracis str. CDC 684], g... gi\|49177000, gi\|... - gi\|49183073\|ref\|YP_026325.1\| TatD family deoxyribonuclease [Bacillus anthracis str. Sterne], gi\|4917... gi\|47500440, gi\|... - gi\|47525292\|ref\|YP_016641.1\| TatD family deoxyribonuclease [Bacillus anthracis str. 'Ames Ancestor']... gi\|30253550, gi\|... - gi\|30260229\|ref\|NP_842606.1\| TatD family deoxyribonuclease [Bacillus anthracis str. Ames], gi\|302535... gi\|21398002, gi\|... - gi\|65317499\|ref\|ZP_00390458.1\| COG0084: Mg-dependent DNase [Bacillus anthracis str. A2012], ref\|NP_6...	237.0	[0..9]	[291..1]
gi\|89207208, gi\|... - gi\|89207208\|ref\|ZP_01185754.1\| TatD-related deoxyribonuclease [Bacillus weihenstephanensis KBAB4], g... gi\|229131047, gi... - gi\|229131047\|ref\|ZP_04259960.1\| Uncharacterized deoxyribonuclease yabD [Bacillus cereus BDRD-ST196],... gi\|228751693, gi... - gi\|229009549\|ref\|ZP_04166776.1\| Uncharacterized deoxyribonuclease yabD [Bacillus mycoides DSM 2048],... gi\|229165028, gi... - gi\|229165028\|ref\|ZP_04292824.1\| Uncharacterized deoxyribonuclease yabD [Bacillus cereus AH621], gi\|2...	237.0	[0..9]	[291..1]

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Predicted Domain #1

Region A:
Residues: [1-292]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFDPTGYTL AHEHLHIDLS GFKNNVDCRL DQYAFICQEM NDLMTRGVRN VIEMTNRYMG  60
   61 RNAQFMLDVM RETGINVVAC TGYYQDAFFP EHVATRSVQE LAQEMVDEIE QGIDGTELKA 120
  121 GIIAEIGTSE GKITPLEEKV FIAAALAHNQ TGRPISTHTS FSTMGLEQLA LLQAHGVDLS 180
  181 RVTVGHCDLK DNLDNILKMI DLGAYVQFDT IGKNSYYPDE KRIAMLHALR DRGLLNRVML 240
  241 SMDITRRSHL KANGGYGYDY LLTTFIPQLR QSGFSQADVD VMLRENPSQF FQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	56.69897
Match:	1bf6A
Description:	Phosphotriesterase homology protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.072432847481	bayes_pls_golite062009
hydrolase activity	1.1112487231896	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	0.481958484200481	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: