YRC Public Data Repository - Protein Structure Prediction

Protein:	PA1_ECOLI
Organism:	Escherichia coli
Length:	289 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PA1_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|73857810, gi\|... - gi\|74314333\|ref\|YP_312752.1\| phospholipase A [Shigella sonnei Ss046], gi\|73857810\|gb\|AAZ90517.1\| out...	463.0	[0..1]	[289..1]
gi\|117626080, gi... - gi\|117626080\|ref\|YP_859403.1\| phospholipase A [Escherichia coli APEC O1], gi\|115515204\|gb\|ABJ03279.1... gi\|191174268, gi... - gi\|75236872\|ref\|ZP_00720941.1\| COG2829: Outer membrane phospholipase A [Escherichia coli F11], gi\|19... gi\|26110991, gi\|... - gi\|26250561\|ref\|NP_756601.1\| phospholipase A [Escherichia coli CFT073], gi\|26110991\|gb\|AAN83175.1\|AE... gi\|91213346, gi\|... - gi\|91213346\|ref\|YP_543332.1\| phospholipase A [Escherichia coli UTI89], gi\|91074920\|gb\|ABE09801.1\| ph... gi\|110644146, gi... - gi\|110644146\|ref\|YP_671876.1\| phospholipase A [Escherichia coli 536], gi\|110345738\|gb\|ABG71975.1\| ph... gi\|227888593, gi... - gi\|227888593\|ref\|ZP_04006398.1\| phospholipase A [Escherichia coli 83972], gi\|227834432\|gb\|EEJ44898.1... gi\|215267221, gi... - gi\|215489149\|ref\|YP_002331580.1\| phospholipase A [Escherichia coli O127:H6 str. E2348/69], gi\|215267... gi\|226903002, gi... - gi\|237702831\|ref\|ZP_04533312.1\| phospholipase A1 [Escherichia sp. 3_2_53FAA], gi\|226903002\|gb\|EEH892... gi\|218692097, gi... - gi\|218692097\|ref\|YP_002400309.1\| phospholipase A [Escherichia coli ED1a], gi\|218429661\|emb\|CAR10482.... gi\|218367654, gi... - gi\|218560885\|ref\|YP_002393798.1\| phospholipase A [Escherichia coli S88], gi\|218367654\|emb\|CAR05439.1...	462.0	[0..1]	[289..1]
gi\|253326597, gi... - gi\|254290516\|ref\|YP_003056264.1\| outer membrane phospholipase A [Escherichia coli BL21(DE3)], gi\|253... gi\|251787080, gi... - gi\|251787080\|ref\|YP_003001384.1\| hypothetical protein B21_03649 [Escherichia coli BL21], gi\|24237935... gi\|194422441, gi... - gi\|83585932\|ref\|ZP_00924571.1\| COG2829: Outer membrane phospholipase A [Escherichia coli 101-1], gi\|... gi\|253975667, gi... - gi\|254163766\|ref\|YP_003046874.1\| outer membrane phospholipase A [Escherichia coli B str. REL606], gi...	462.0	[0..1]	[289..1]
gi\|75238271, gi\|... - gi\|75238271\|ref\|ZP_00722270.1\| COG2829: Outer membrane phospholipase A [Escherichia coli E110019], g...	462.0	[0..1]	[289..1]
gi\|187732481, gi... - gi\|75177784\|ref\|ZP_00697849.1\| COG2829: Outer membrane phospholipase A [Shigella boydii BS512], gi\|1...	461.0	[0..1]	[289..1]
gi\|148220 - gi\|148220\|gb\|AAA67617.1\| detergent-resistant phospholipase A [Escherichia coli] gi\|148220\|gb\|AAA... - detergent-resistant phospholipase A [Escherichia coli]	459.0	[0..1]	[289..1]
gi\|165921896, gi... - gi\|165926372\|ref\|ZP_02222204.1\| phospholipase A1 [Yersinia pestis biovar Orientalis str. F1991016], ... gi\|149289416, gi... - gi\|153997110\|ref\|ZP_02022243.1\| phospholipase A [Yersinia pestis CA88-4125], gi\|149289416\|gb\|EDM3949... gi\|166205245, gi... - gi\|166213572\|ref\|ZP_02239607.1\| phospholipase A1 [Yersinia pestis biovar Antiqua str. B42003004], gi... gi\|145212397, gi... - gi\|145600701\|ref\|YP_001164777.1\| phospholipase A [Yersinia pestis Pestoides F], gi\|145212397\|gb\|ABP4... gi\|166011636, gi... - gi\|166011636\|ref\|ZP_02232534.1\| phospholipase A1 [Yersinia pestis biovar Antiqua str. E1979001], gi\|... gi\|167420999, gi... - gi\|167420999\|ref\|ZP_02312752.1\| phospholipase A1 [Yersinia pestis biovar Orientalis str. MG05-1020],... gi\|167048716, gi... - gi\|167401823\|ref\|ZP_02307311.1\| phospholipase A1 [Yersinia pestis biovar Antiqua str. UG05-0454], gi... gi\|170026210, gi... - gi\|170026210\|ref\|YP_001722715.1\| phospholipase A [Yersinia pseudotuberculosis YPIII], gi\|169752744\|g... gi\|167426217, gi... - gi\|167426217\|ref\|ZP_02317970.1\| phospholipase A1 [Yersinia pestis biovar Mediaevalis str. K1973002],... gi\|229706106, gi... - gi\|229837163\|ref\|ZP_04457328.1\| outer membrane phospholipase A [Yersinia pestis Pestoides A], gi\|229... gi\|229695889, gi... - gi\|229839523\|ref\|ZP_04459682.1\| outer membrane phospholipase A [Yersinia pestis biovar Orientalis st... gi\|5640168 - gi\|5640168\|emb\|CAB51586.1\| phospholipase A [Yersinia pseudotuberculosis] gi\|108773944, gi... - gi\|229900468\|ref\|ZP_04515597.1\| outer membrane phospholipase A [Yersinia pestis Nepal516], gi\|229682... gi\|25288904 - pir\|\|AB0467 phospholipase A [imported] - Yersinia pestis (strain CO92) gi\|45442966, gi\|... - gi\|45442966\|ref\|NP_994505.1\| phospholipase A [Yersinia pestis biovar Microtus str. 91001], gi\|454378... gi\|21957084, gi\|... - gi\|22124311\|ref\|NP_667734.1\| phospholipase A [Yersinia pestis KIM], gi\|21957084\|gb\|AAM83985.1\|AE0136... gi\|16123969, gi\|... - gi\|218930837\|ref\|YP_002348712.1\| phospholipase A [Yersinia pestis CO92], gi\|16123969\|ref\|NP_407282.1... gi\|51587838, gi\|... - gi\|51594556\|ref\|YP_068747.1\| phospholipase A [Yersinia pseudotuberculosis IP 32953], gi\|51587838\|emb... gi\|89104205, gi\|... - gi\|89104205\|ref\|ZP_01176755.1\| COG2829: Outer membrane phospholipase A [Yersinia pestis biovar Orien... gi\|108778099, gi... - gi\|108806186\|ref\|YP_650102.1\| phospholipase A [Yersinia pestis Antiqua], gi\|108778099\|gb\|ABG12157.1\|... gi\|186893558, gi... - gi\|186893558\|ref\|YP_001870670.1\| phospholipase A [Yersinia pseudotuberculosis PB1/+], gi\|186696584\|g... gi\|117672039, gi... - gi\|77630732\|ref\|ZP_00793318.1\| COG2829: Outer membrane phospholipase A [Yersinia pseudotuberculosis ...	444.0	[0..1]	[289..1]
gi\|77632822, gi\|... - gi\|77632822\|ref\|ZP_00795010.1\| COG2829: Outer membrane phospholipase A [Yersinia pestis Angola], gi\|...	442.0	[0..1]	[289..1]
gi\|4104238 - gi\|4104238\|gb\|AAD03498.1\| outer membrane phospholipase A precursor; detergent resistent phospholipas...	439.0	[0..1]	[289..1]
gi\|77960559 - gi\|77960559\|ref\|ZP_00824425.1\| COG2829: Outer membrane phospholipase A [Yersinia mollaretii ATCC 439...	436.0	[0..1]	[289..1]

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Predicted Domain #1

Region A:
Residues: [1-289]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRTLQGWLLP VFMLPMAVYA QEATVKEVHD APAVRGSIIA NMLQEHDNPF TLYPYDTNYL  60
   61 IYTQTSDLNK EAIASYDWAE NARKDEVKFQ LSLAFPLWRG ILGPNSVLGA SYTQKSWWQL 120
  121 SNSEESSPFR ETNYEPQLFL GFATDYRFAG WTLRDVEMGY NHDSNGRSDP TSRSWNRLYT 180
  181 RLMAENGNWL VEVKPWYVVG NTDDNPDITK YMGYYQLKIG YHLGDAVLSA KGQYNWNTGY 240
  241 GGAELGLSYP ITKHVRLYTQ VYSGYGESLI DYNFNQTRVG VGVMLNDLF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	122.0
Match:	1fw2A
Description:	Outer membrane phospholipase A (OMPLA)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.142826098671881	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: