YRC Public Data Repository - Protein Structure Prediction

Protein:	NUOE_ECOLI
Organism:	Escherichia coli
Length:	166 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NUOE_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|50800491 - gi\|50800491\|ref\|XP_424129.1\| PREDICTED: similar to NADH2 dehydrogenase (ubiquinone) (EC 1.6.5.3) 24K...	238.0	[0..2]	[166..87]
gi\|73962198 - gi\|73962198\|ref\|XP_537328.2\| PREDICTED: similar to NADH dehydrogenase (ubiquinone) flavoprotein 2, 2...	236.0	[0..3]	[166..45]
gi\|62857879, gi\|... - gi\|89272040\|emb\|CAJ83184.1\| NADH dehydrogenase (ubiquinone) flavoprotein 2 [Xenopus tropicalis], gi\|...	235.0	[0..3]	[166..39]
gi\|109121568 - gi\|109121568\|ref\|XP_001099724.1\| PREDICTED: similar to NADH dehydrogenase (ubiquinone) flavoprotein ...	235.0	[0..3]	[166..45]
NDUV2_BOVIN - NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial OS=Bos taurus GN=NDUFV2 PE=1 SV=3	233.0	[0..3]	[166..45]
NDUV2_PONPY - NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial OS=Pongo pygmaeus GN=NDUFV2 PE=2 SV=1 gi\|111661782 - gi\|111661782\|gb\|ABH12155.1\| mitochondrial complex I subunit NDUFV2 [Gorilla gorilla] NDUV2_PONAB - NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial OS=Pongo abelii GN=NDUFV2 PE=2 SV=1 NDUV2_GORGO - NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial OS=Gorilla gorilla gorilla GN=NDUFV2 P...	233.0	[0..3]	[166..45]
NDUV2_PANTR - NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial OS=Pan troglodytes GN=NDUFV2 PE=2 SV=1	232.0	[0..3]	[166..45]
NDUFV2 - NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa gi\|123984347, gi... - gi\|123998275\|gb\|ABM86739.1\| NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa [synthetic constru...	232.0	[0..3]	[166..45]

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Predicted Domain #1

Region A:
Residues: [1-166]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHENQQPQTE AFELSAAERE AIEHEMHHYE DPRAASIEAL KIVQKQRGWV PDGAIHAIAD  60
   61 VLGIPASDVE GVATFYSQIF RQPVGRHVIR YCDSVVCHIN GYQGIQAALE KKLNIKPGQT 120
  121 TFDGRFTLLP TCCLGNCDKG PNMMIDEDTH AHLTPEAIPE LLERYK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	40.0
Match:	2fug2
Description:	Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
NADH dehydrogenase activity	9.90105969982332	bayes_pls_golite062009
NADH dehydrogenase (ubiquinone) activity	8.92078442660684	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	8.81403581008074	bayes_pls_golite062009
NADH dehydrogenase (quinone) activity	8.78237088091479	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor	8.15019987387908	bayes_pls_golite062009
oxidoreductase activity	4.56566449113494	bayes_pls_golite062009
electron carrier activity	1.9747415675561	bayes_pls_golite062009
catalytic activity	0.672192331361968	bayes_pls_golite062009
protein binding	0.195947179962724	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: