YRC Public Data Repository - Protein Structure Prediction

Protein:	NFNB_ECOLI
Organism:	Escherichia coli
Length:	217 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NFNB_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|151939914, gi... - gi\|75854892\|ref\|ZP_00762561.1\| COG0778: Nitroreductase [Vibrio sp. Ex25], gi\|254227302\|ref\|ZP_049207...	183.0	[0..1]	[217..1]
gi\|104781425, gi... - gi\|95110412\|emb\|CAK15120.1\| oxygen-insensitive NADPH nitroreductase [Pseudomonas entomophila L48], g... gi\|95110412 - gi\|95110412\|emb\|CAK15120.1\| oxygen-insensitive NADPH nitroreductase [Pseudomonas entomophila L48]	183.0	[0..1]	[217..1]
gi\|28901446, gi\|... - gi\|28901446\|ref\|NP_801101.1\| dihydropteridine reductase [Vibrio parahaemolyticus RIMD 2210633], gi\|2... gi\|28809993 - gi\|28809993\|dbj\|BAC62934.1\| oxygen-insensitive NAD(P)H nitroreductase [Vibrio parahaemolyticus RIMD ...	183.0	[0..1]	[217..1]
gi\|91191969, gi\|... - gi\|91223156\|ref\|ZP_01258422.1\| oxygen-insensitive NAD(P)H nitroreductase [Vibrio alginolyticus 12G01... gi\|149747033, gi... - gi\|153839444\|ref\|ZP_01992111.1\| oxygen-insensitive NAD(P)H nitroreductase [Vibrio parahaemolyticus A...	182.0	[0..1]	[217..1]
gi\|224466938, gi... - gi\|224582411\|ref\|YP_002636209.1\| oxygen-insensitive NAD(P)H nitroreductase [Salmonella enterica subs... gi\|62179179, gi\|... - gi\|62179179\|ref\|YP_215596.1\| dihydropteridine reductase [Salmonella enterica subsp. enterica serovar...	181.0	[0..1]	[217..1]
gi\|148548471, gi... - gi\|82734984\|ref\|ZP_00897847.1\| oxygen-insensitive NAD(P)H nitroreductase [Pseudomonas putida F1], gi... tr\|I7BH12\|I7BH12... - Dihydropteridine reductase OS=Pseudomonas putida (strain DOT-T1E) GN=nfnB PE=4 SV=1	181.0	[0..1]	[217..1]
NFNB_SALTY - Oxygen-insensitive NAD(P)H nitroreductase OS=Salmonella typhimurium GN=nfnB PE=3 SV=1 NFNB_SALTY - Oxygen-insensitive NAD(P)H nitroreductase OS=Salmonella typhimurium GN=nfnB PE=1 SV=1 lcl\|NC_016856.1_... - [gene=nfnB] [protein=dihydropteridine reductase] [protein_id=YP_005236282.1] [location=complement(63... gi\|205330954, gi... - gi\|205330954\|gb\|EDZ17718.1\| oxygen-insensitive NAD [Salmonella enterica subsp. enterica serovar 4,[5... NFSB_SALTY - Oxygen-insensitive NAD(P)H nitroreductase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 70... gi\|56128542, gi\|... - gi\|56414285\|ref\|YP_151360.1\| dihydropteridine reductase [Salmonella enterica subsp. enterica serovar... gi\|197939684, gi... - gi\|198245168\|ref\|YP_002214572.1\| oxygen-insensitive NAD [Salmonella enterica subsp. enterica serovar... gi\|197363207, gi... - gi\|197363207\|ref\|YP_002142844.1\| dihydropteridine reductase [Salmonella enterica subsp. enterica ser... gi\|197243981, gi... - gi\|197265726\|ref\|ZP_03165800.1\| oxygen-insensitive NAD [Salmonella enterica subsp. enterica serovar ... gi\|205350107, gi... - gi\|205350107\|gb\|EDZ36738.1\| oxygen-insensitive NAD [Salmonella enterica subsp. enterica serovar Hada...	181.0	[0..1]	[217..1]
gi\|12232330 - gi\|12232330\|gb\|AAG48378.1\| retro-nitroreductase [Enterobacter cloacae]	181.0	[0..1]	[216..1]
gi\|24983992, gi\|... - gi\|26989155\|ref\|NP_744580.1\| dihydropteridine reductase [Pseudomonas putida KT2440], gi\|24983992\|gb\|... gi\|22347819 - gi\|22347819\|gb\|AAM95987.1\| oxygen-insensitive NADPH nitroreductase [Pseudomonas putida]	181.0	[0..1]	[217..1]
gi\|78363654, gi\|... - gi\|78485368\|ref\|YP_391293.1\| dihydropteridine reductase [Thiomicrospira crunogena XCL-2], gi\|7836365...	180.0	[0..1]	[217..1]

Back

Predicted Domain #1

Region A:
Residues: [1-217]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDIISVALKR HSTKAFDASK KLTPEQAEQI KTLLQYSPSS TNSQPWHFIV ASTEEGKARV  60
   61 AKSAAGNYVF NERKMLDASH VVVFCAKTAM DDVWLKLVVD QEDADGRFAT PEAKAANDKG 120
  121 RKFFADMHRK DLHDDAEWMA KQVYLNVGNF LLGVAALGLD AVPIEGFDAA ILDAEFGLKE 180
  181 KGYTSLVVVP VGHHSVEDFN ATLPKSRLPQ NITLTEV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	44.69897
Match:	1ds7A
Description:	Oxygen-insensitive NAD(P)H nitroreductase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.11149969304282	bayes_pls_golite062009
oxidoreductase activity	0.223640985940171	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: