YRC Public Data Repository - Protein Structure Prediction

Protein:	NANE_ECOLI
Organism:	Escherichia coli
Length:	229 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NANE_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|94427889, gi\|... - gi\|94500031\|ref\|ZP_01306566.1\| indole-3-glycerol-phosphate synthase [Oceanobacter sp. RED65], gi\|944...	162.0	[0..2]	[224..57]
gi\|110647996, gi... - gi\|110834885\|ref\|YP_693744.1\| indole-3-glycerol phosphate synthase [Alcanivorax borkumensis SK2], gi...	161.0	[0..2]	[224..57]
gi\|110735227 - gi\|110735227\|gb\|ABG89184.1\| putative amino sugar epimerase [Mannheimia haemolytica]	161.0	[0..1]	[227..1]
gi\|207089716 - gi\|207089716\|gb\|EDZ66987.1\| indole-3-glycerol phosphate synthase [Nitrosococcus oceani AFC27] gi\|224410062, gi... - gi\|254433383\|ref\|ZP_05046891.1\| indole-3-glycerol phosphate synthase [Nitrosococcus oceani AFC27], g... gi\|77165955, gi\|... - gi\|77165955\|ref\|YP_344480.1\| indole-3-glycerol-phosphate synthase [Nitrosococcus oceani ATCC 19707],...	160.0	[0..2]	[226..58]
gi\|145273768, gi... - gi\|145641477\|ref\|ZP_01797055.1\| putative N-acetylmannosamine-6-phosphate 2-epimerase [Haemophilus in... gi\|145641477 - gi\|145641477\|ref\|ZP_01797055.1\| putative N-acetylmannosamine-6-phosphate 2-epimerase [Haemophilus in... gi\|145633572, gi... - gi\|145633572\|ref\|ZP_01789300.1\| putative N-acetylmannosamine-6-phosphate 2-epimerase [Haemophilus in... gi\|46128846 - gi\|46128846\|ref\|ZP_00154355.2\| COG3010: Putative N-acetylmannosamine-6-phosphate epimerase [Haemophi... gi\|53733109 - gi\|53733109\|ref\|ZP_00155988.2\| COG3010: Putative N-acetylmannosamine-6-phosphate epimerase [Haemophi...	158.0	[0..1]	[227..1]
gi\|145267452, gi... - gi\|145635308\|ref\|ZP_01791011.1\| N-acetylmannosamine-6-phosphate 2-epimerase [Haemophilus influenzae ... gi\|68056952, gi\|... - gi\|68248753\|ref\|YP_247865.1\| N-acetylmannosamine-6-phosphate 2-epimerase [Haemophilus influenzae 86-...	158.0	[0..1]	[227..1]
gi\|113460844, gi... - gi\|113460844\|ref\|YP_718911.1\| N-acetylmannosamine-6-phosphate 2-epimerase [Haemophilus somnus 129PT]...	156.0	[0..1]	[227..1]
gi\|48861005, gi\|... - gi\|90020401\|ref\|YP_526228.1\| indole-3-glycerol phosphate synthase [Saccharophagus degradans 2-40], g...	156.0	[0..2]	[224..58]
gi\|83648766, gi\|... - gi\|83648766\|ref\|YP_437201.1\| indole-3-glycerol phosphate synthase [Hahella chejuensis KCTC 2396], gi...	156.0	[0..2]	[224..58]
gi\|170717330, gi... - gi\|32030219\|ref\|ZP_00133111.1\| COG3010: Putative N-acetylmannosamine-6-phosphate epimerase [Haemophi...	156.0	[0..1]	[227..1]

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Predicted Domain #1

Region A:
Residues: [1-229]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLLAQLDQK IAANGGLIVS CQPVPDSPLD KPEIVAAMAL AAEQAGAVAI RIEGVANLQA  60
   61 TRAVVSVPII GIVKRDLEDS PVRITAYIED VDALAQAGAD IIAIDGTDRP RPVPVETLLA 120
  121 RIHHHGLLAM TDCSTPEDGL ACQKLGAEII GTTLSGYTTP ETPEEPDLAL VKTLSDAGCR 180
  181 VIAEGRYNTP AQAADAMRHG AWAVTVGSAI TRLEHICQWY NTAMKKAVL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	32.522879
Match:	1y0eA
Description:	Crystal structure of putative ManNAc-6-P epimerase from Staphylococcus aureus (strain N315)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.44231061702877	bayes_pls_golite062009
ribulose-phosphate 3-epimerase activity	1.69939085947699	bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting aldoses and ketoses	1.36492964250879	bayes_pls_golite062009
intramolecular oxidoreductase activity	1.19338801680976	bayes_pls_golite062009
N-acylglucosamine-6-phosphate 2-epimerase activity	1.0760062330129	bayes_pls_golite062009
isomerase activity	0.935800409577999	bayes_pls_golite062009
racemase and epimerase activity, acting on carbohydrates and derivatives	0.764608070506109	bayes_pls_golite062009
racemase and epimerase activity	0.288948763149344	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: