YRC Public Data Repository - Protein Structure Prediction

Protein:	MUTT_ECOLI
Organism:	Escherichia coli
Length:	129 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MUTT_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|22298621, gi\|... - gi\|22298621\|ref\|NP_681868.1\| adenine glycosylase [Thermosynechococcus elongatus BP-1], gi\|22294801\|d...	138.0	[0..1]	[128..235]
gi\|75701836, gi\|... - gi\|75908111\|ref\|YP_322407.1\| Mutator MutT [Anabaena variabilis ATCC 29413], gi\|75701836\|gb\|ABA21512....	137.0	[0..2]	[129..8]
gi\|53762849, gi\|... - gi\|81299484\|ref\|YP_399692.1\| A/G-specific DNA-adenine glycosylase [Synechococcus elongatus PCC 7942]... gi\|56750865, gi\|... - gi\|56750865\|ref\|YP_171566.1\| mutator MutT protein [Synechococcus elongatus PCC 6301], gi\|56685824\|db...	136.0	[0..1]	[128..229]
gi\|83757907, gi\|... - gi\|83816513\|ref\|YP_446225.1\| A/G-specific adenine glycosylase [Salinibacter ruber DSM 13855], gi\|837...	135.0	[0..2]	[128..219]
gi\|84667594, gi\|... - gi\|84684615\|ref\|ZP_01012516.1\| mutator mutT protein [Rhodobacterales bacterium HTCC2654], gi\|8466759...	135.0	[0..1]	[129..1]
gi\|127514372, gi... - gi\|78366245\|ref\|ZP_00836527.1\| Mutator MutT [Shewanella sp. PV-4], gi\|78361833\|gb\|EAP03655.1\| Mutato...	135.0	[0..1]	[129..1]
gi\|70732104, gi\|... - gi\|70732104\|ref\|YP_261860.1\| hypothetical protein PFL_4779 [Pseudomonas fluorescens Pf-5], gi\|683464...	133.0	[0..2]	[127..27]
gi\|114049098, gi... - gi\|78690771\|ref\|ZP_00855410.1\| Mutator MutT [Shewanella sp. MR-7], gi\|78509827\|gb\|EAP23210.1\| Mutato...	131.0	[0..2]	[128..3]
tr\|Q87WZ6\|Q87WZ6... - MutT/nudix family protein OS=Pseudomonas syringae pv. tomato (strain DC3000) GN=PSPTO_4397 PE=4 SV=1 gi\|28854783, gi\|... - gi\|28871532\|ref\|NP_794151.1\| hypothetical protein PSPTO_4397 [Pseudomonas syringae pv. tomato str. D...	131.0	[0..1]	[127..1]
gi\|114769747, gi... - gi\|114769747\|ref\|ZP_01447357.1\| NTP pyrophosphohydrolase [alpha proteobacterium HTCC2255], gi\|114549... gi\|114769747 - gi\|114769747\|ref\|ZP_01447357.1\| NTP pyrophosphohydrolase [alpha proteobacterium HTCC2255] gi\|161170243 - gi\|161170243\|gb\|ABX59213.1\| NTP pyrophosphohydrolase [uncultured marine bacterium EB000_55B11]	131.0	[0..1]	[129..1]

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Predicted Domain #1

Region A:
Residues: [1-129]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKLQIAVGI IRNENNEIFI TRRAADAHMA NKLEFPGGKI EMGETPEQAV VRELQEEVGI  60
   61 TPQHFSLFEK LEYEFPDRHI TLWFWLVERW EGEPWGKEGQ PGEWMSLVGL NADDFPPANE 120
  121 PVIAKLKRL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	27.0
Match:	1mutA
Description:	NMR STUDY OF MUTT ENZYME, A NUCLEOSIDE TRIPHOSPHATE PYROPHOSPHOHYDROLASE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.86119802438676	bayes_pls_golite062009
hydrolase activity	0.97790691270817	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.544115189438	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.54377405132398	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: