YRC Public Data Repository - Protein Structure Prediction

Protein:	MURB_ECOLI
Organism:	Escherichia coli
Length:	342 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MURB_ECOLI.

Description	E-value	Query Range	Subject Range
MURB_MANSM - UDP-N-acetylenolpyruvoylglucosamine reductase OS=Mannheimia succiniciproducens (strain MBEL55E) GN=m...	303.0	[0..3]	[342..2]
gi\|290456 - gi\|290456\|gb\|AAA24185.1\| UDP-N-acetylpyruvoylglucosamine reductase [Escherichia coli] gi\|83584483, gi\|... - gi\|83584483\|ref\|ZP_00923165.1\| COG0812: UDP-N-acetylmuramate dehydrogenase [Escherichia coli 101-1],... gi\|170022020, gi... - gi\|170022020\|ref\|YP_001726974.1\| UDP-N-acetylenolpyruvoylglucosamine reductase [Escherichia coli ATC... gi\|251787234, gi... - gi\|251787234\|ref\|YP_003001538.1\| hypothetical protein B21_03806 [Escherichia coli BL21], gi\|24237950... gi\|253775394, gi... - gi\|254290668\|ref\|YP_003056416.1\| UDP-N-acetylenolpyruvoylglucosamine reductase [Escherichia coli BL2... gi\|254163918, gi... - gi\|254163918\|ref\|YP_003047026.1\| UDP-N-acetylenolpyruvoylglucosamine reductase [Escherichia coli B s...	301.0	[0..1]	[342..1]
gi\|208812779, gi... - gi\|208812779\|ref\|ZP_03254108.1\| UDP-N-acetylenolpyruvoylglucosamine reductase [Escherichia coli O157... gi\|208739222, gi... - gi\|208819099\|ref\|ZP_03259419.1\| UDP-N-acetylenolpyruvoylglucosamine reductase [Escherichia coli O157... gi\|209157887, gi... - gi\|209396487\|ref\|YP_002273492.1\| UDP-N-acetylenolpyruvoylglucosamine reductase [Escherichia coli O15... gi\|13364375, gi\|... - gi\|15834153\|ref\|NP_312926.1\| UDP-N-acetylenolpyruvoylglucosamine reductase [Escherichia coli O157:H7... gi\|217326068, gi... - gi\|217326068\|ref\|ZP_03442152.1\| UDP-N-acetylenolpyruvoylglucosamine reductase [Escherichia coli O157... gi\|168786836, gi... - gi\|189373328\|gb\|EDU91744.1\| UDP-N-acetylenolpyruvoylglucosamine reductase [Escherichia coli O157:H7 ... gi\|168802901, gi... - gi\|189375263\|gb\|EDU93679.1\| UDP-N-acetylenolpyruvoylglucosamine reductase [Escherichia coli O157:H7 ... gi\|195940694 - gi\|195940694\|ref\|ZP_03086076.1\| UDP-N-acetylenolpyruvoylglucosamine reductase [Escherichia coli O157... gi\|208805744, gi... - gi\|208805744\|ref\|ZP_03248081.1\| UDP-N-acetylenolpyruvoylglucosamine reductase [Escherichia coli O157... gi\|189364933, gi... - gi\|189364933\|gb\|EDU83349.1\| UDP-N-acetylenolpyruvoylglucosamine reductase [Escherichia coli O157:H7 ... gi\|189359749, gi... - gi\|189359749\|gb\|EDU78168.1\| UDP-N-acetylenolpyruvoylglucosamine reductase [Escherichia coli O157:H7 ... gi\|168778066, gi... - gi\|187766851\|gb\|EDU30695.1\| UDP-N-acetylenolpyruvoylglucosamine reductase [Escherichia coli O157:H7 ... gi\|168780897, gi... - gi\|189001520\|gb\|EDU70506.1\| UDP-N-acetylenolpyruvoylglucosamine reductase [Escherichia coli O157:H7 ... gi\|168752647, gi... - gi\|188013585\|gb\|EDU51707.1\| UDP-N-acetylenolpyruvoylglucosamine reductase [Escherichia coli O157:H7 ... gi\|168759133, gi... - gi\|189354242\|gb\|EDU72661.1\| UDP-N-acetylenolpyruvoylglucosamine reductase [Escherichia coli O157:H7 ... gi\|12518898, gi\|... - gi\|15804566\|ref\|NP_290607.1\| UDP-N-acetylenolpyruvoylglucosamine reductase [Escherichia coli O157:H7... gi\|209751908, gi... - pir\|\|H86088 UDP-N-acetylenolpyruvoylglucosamine reductase [imported] - Escherichia coli (strain O157... gi\|254595375, gi... - gi\|254795975\|ref\|YP_003080812.1\| UDP-N-acetylenolpyruvoylglucosamine reductase, FAD-binding [Escheri... MURB_ECO57 - UDP-N-acetylenolpyruvoylglucosamine reductase OS=Escherichia coli O157:H7 GN=murB PE=3 SV=1	300.0	[0..1]	[342..1]
MURB_SHIDS - UDP-N-acetylenolpyruvoylglucosamine reductase OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=m...	300.0	[0..1]	[342..1]
gi\|82721436, gi\|... - gi\|82741167\|ref\|ZP_00903894.1\| UDP-N-acetylenolpyruvoylglucosamine reductase [Shewanella sp. W3-18-1... gi\|145566548, gi... - gi\|77813811\|ref\|ZP_00813084.1\| UDP-N-acetylenolpyruvoylglucosamine reductase [Shewanella putrefacien...	300.0	[0..1]	[338..3]
gi\|193066776, gi... - gi\|75255020\|ref\|ZP_00726936.1\| COG0812: UDP-N-acetylmuramate dehydrogenase [Escherichia coli E22], g... gi\|75226860, gi\|... - gi\|75226860\|ref\|ZP_00713765.1\| COG0812: UDP-N-acetylmuramate dehydrogenase [Escherichia coli B7A], g... gi\|192954858, gi... - gi\|75214528\|ref\|ZP_00713096.1\| COG0812: UDP-N-acetylmuramate dehydrogenase [Escherichia coli E110019... gi\|194411490, gi... - gi\|75208236\|ref\|ZP_00708601.1\| COG0812: UDP-N-acetylmuramate dehydrogenase [Escherichia coli B171], ... gi\|75197841, gi\|... - gi\|75197841\|ref\|ZP_00707911.1\| COG0812: UDP-N-acetylmuramate dehydrogenase [Escherichia coli HS], gi... gi\|218697684, gi... - gi\|218697684\|ref\|YP_002405351.1\| UDP-N-acetylenolpyruvoylglucosamine reductase [Escherichia coli 559...	299.0	[0..1]	[342..1]
gi\|91212782, gi\|... - gi\|91212782\|ref\|YP_542768.1\| UDP-N-acetylenolpyruvoylglucosamine reductase [Escherichia coli UTI89],... gi\|227837535, gi... - gi\|227885497\|ref\|ZP_04003302.1\| UDP-N-acetylenolpyruvoylglucosamine reductase [Escherichia coli 8397... MURB_ECOL6 - UDP-N-acetylenolpyruvoylglucosamine reductase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928... gi\|117626241, gi... - gi\|117626241\|ref\|YP_859564.1\| UDP-N-acetylenolpyruvoylglucosamine reductase [Escherichia coli APEC O... gi\|226903055, gi... - gi\|237702742\|ref\|ZP_04533223.1\| UDP-N-acetylenolpyruvoylglucosamine reductase [Escherichia sp. 3_2_5... gi\|218561043, gi... - gi\|218561043\|ref\|YP_002393956.1\| UDP-N-acetylenolpyruvoylglucosamine reductase [Escherichia coli S88... gi\|215489309, gi... - gi\|215489309\|ref\|YP_002331740.1\| UDP-N-acetylenolpyruvoylglucosamine reductase [Escherichia coli O12... MURB_ECOL6 - UDP-N-acetylenolpyruvoylglucosamine reductase OS=Escherichia coli O6 GN=murB PE=3 SV=1	299.0	[0..1]	[342..1]
MURB_SHIBS - UDP-N-acetylenolpyruvoylglucosamine reductase OS=Shigella boydii serotype 4 (strain Sb227) GN=murB P... gi\|187731217, gi... - gi\|75176640\|ref\|ZP_00696768.1\| COG0812: UDP-N-acetylmuramate dehydrogenase [Shigella boydii BS512], ...	299.0	[0..1]	[342..1]
MURB_SHIFL - UDP-N-acetylenolpyruvoylglucosamine reductase OS=Shigella flexneri GN=murB PE=3 SV=1 gi\|110807827, gi... - gi\|110807827\|ref\|YP_691347.1\| UDP-N-acetylenolpyruvoylglucosamine reductase [Shigella flexneri 5 str... gi\|24054554, gi\|... - gi\|24115262\|ref\|NP_709772.1\| UDP-N-acetylenolpyruvoylglucosamine reductase [Shigella flexneri 2a str... gi\|30043001, gi\|... - gi\|30064741\|ref\|NP_838912.1\| UDP-N-acetylenolpyruvoylglucosamine reductase [Shigella flexneri 2a str... MURB_SHISS - UDP-N-acetylenolpyruvoylglucosamine reductase OS=Shigella sonnei (strain Ss046) GN=murB PE=3 SV=1 gi\|75510803, gi\|... - gi\|75510803\|ref\|ZP_00733624.1\| COG0812: UDP-N-acetylmuramate dehydrogenase [Escherichia coli 53638],...	298.0	[0..1]	[342..1]
gi\|157080183, gi... - gi\|75188707\|ref\|ZP_00701974.1\| COG0812: UDP-N-acetylmuramate dehydrogenase [Escherichia coli E24377A...	297.0	[0..1]	[342..1]

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Predicted Domain #1

Region A:
Residues: [1-342]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNHSLKPWNT FGIDHNAQHI VCAEDEQQLL NAWQYATAEG QPVLILGEGS NVLFLEDYRG  60
   61 TVIINRIKGI EIHDEPDAWY LHVGAGENWH RLVKYTLQEG MPGLENLALI PGCVGSSPIQ 120
  121 NIGAYGVELQ RVCAYVDSVE LATGKQVRLT AKECRFGYRD SIFKHEYQDR FAIVAVGLRL 180
  181 PKEWQPVLTY GDLTRLDPTT VTPQQVFNAV CHMRTTKLPD PKVNGNAGSF FKNPVVSAET 240
  241 AKALLSQFPT APNYPQADGS VKLAAGWLID QCQLKGMQIG GAAVHRQQAL VLINEDNAKS 300
  301 EDVVQLAHHV RQKVGEKFNV WLEPEVRFIG ASGEVSAVET IS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	82.045757
Match:	1mbbA
Description:	OXIDOREDUCTASE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
UDP-N-acetylmuramate dehydrogenase activity	3.31671992605898	bayes_pls_golite062009
catalytic activity	1.27762227752756	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: