YRC Public Data Repository - Protein Structure Prediction

Protein:	MUKF_ECOLI
Organism:	Escherichia coli
Length:	440 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MUKF_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|77963105 - gi\|77963105\|ref\|ZP_00826918.1\| COG3006: Uncharacterized protein involved in chromosome partitioning ...	809.0	[0..1]	[440..1]
gi\|77956205 - gi\|77956205\|ref\|ZP_00820329.1\| COG3006: Uncharacterized protein involved in chromosome partitioning ...	809.0	[0..1]	[440..1]
gi\|77974862 - gi\|77974862\|ref\|ZP_00830400.1\| COG3006: Uncharacterized protein involved in chromosome partitioning ...	809.0	[0..1]	[440..1]
gi\|75210388, gi\|... - gi\|75210388\|ref\|ZP_00710544.1\| COG3006: Uncharacterized protein involved in chromosome partitioning ... gi\|75257362, gi\|... - gi\|75257362\|ref\|ZP_00728878.1\| COG3006: Uncharacterized protein involved in chromosome partitioning ...	808.0	[0..1]	[440..1]
gi\|83571209, gi\|... - gi\|83571209\|ref\|ZP_00922650.1\| COG3006: Uncharacterized protein involved in chromosome partitioning ...	807.0	[0..1]	[440..1]
gi\|191172085, gi... - gi\|75240997\|ref\|ZP_00724886.1\| COG3006: Uncharacterized protein involved in chromosome partitioning ... MUKF_ECOL6 - Chromosome partition protein mukF OS=Escherichia coli O6 GN=mukF PE=3 SV=1 MUKF_ECO45 - Chromosome partition protein MukF OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=mukF PE=3 SV=1 MUKF_ECO81 - Chromosome partition protein MukF OS=Escherichia coli O81 (strain ED1a) GN=mukF PE=3 SV=1 MUKF_ECOL6 - Chromosome partition protein MukF OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=... gi\|227838865, gi... - gi\|227884113\|ref\|ZP_04001918.1\| chromosome partioning protein, Ca2+ binding protein [Escherichia col... gi\|237707090, gi... - gi\|237707090\|ref\|ZP_04537571.1\| condesin subunit F [Escherichia sp. 3_2_53FAA], gi\|226898300\|gb\|EEH8... MUKF_ECOK1 - Chromosome partition protein MukF OS=Escherichia coli O1:K1 / APEC GN=mukF PE=3 SV=1 MUKF_ECOUT - Chromosome partition protein MukF OS=Escherichia coli (strain UTI89 / UPEC) GN=mukF PE=3 SV=1 MUKF_ECOL5 - Chromosome partition protein MukF OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=mukF PE=3 SV...	807.0	[0..1]	[440..1]
gi\|217320356, gi... - gi\|217324135\|ref\|ZP_03440219.1\| chromosome partition protein MukF [Escherichia coli O157:H7 str. TW1... MUKF_ECO5E - Chromosome partition protein MukF OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=mukF PE=3 SV... gi\|208725890, gi... - gi\|208806089\|ref\|ZP_03248426.1\| chromosome partition protein MukF [Escherichia coli O157:H7 str. EC4... gi\|195940078 - gi\|195940078\|ref\|ZP_03085460.1\| condesin subunit F [Escherichia coli O157:H7 str. EC4024] gi\|208822107, gi... - gi\|208822107\|ref\|ZP_03262426.1\| chromosome partition protein MukF [Escherichia coli O157:H7 str. EC4... gi\|208816265, gi... - gi\|208816265\|ref\|ZP_03257444.1\| chromosome partition protein MukF [Escherichia coli O157:H7 str. EC4... gi\|168769918, gi... - gi\|189361109\|gb\|EDU79528.1\| chromosome partition protein MukF [Escherichia coli O157:H7 str. EC4486]... gi\|168762940, gi... - gi\|189366813\|gb\|EDU85229.1\| chromosome partition protein MukF [Escherichia coli O157:H7 str. EC4501]... gi\|189372763, gi... - gi\|189372763\|gb\|EDU91179.1\| chromosome partition protein MukF [Escherichia coli O157:H7 str. EC869],... gi\|187768353, gi... - gi\|187768353\|gb\|EDU32197.1\| chromosome partition protein MukF [Escherichia coli O157:H7 str. EC4196]... gi\|254792121, gi... - gi\|254792121\|ref\|YP_003076958.1\| Involved in chromosome partioning, Ca2+ binding protein [Escherichi... gi\|168757015, gi... - gi\|189355950\|gb\|EDU74369.1\| chromosome partition protein MukF [Escherichia coli O157:H7 str. EC4401]... gi\|13360464, gi\|... - gi\|15830259\|ref\|NP_309032.1\| condesin subunit F [Escherichia coli O157:H7 str. Sakai], gi\|13360464\|d... gi\|188014726, gi... - gi\|188014726\|gb\|EDU52848.1\| chromosome partition protein MukF [Escherichia coli O157:H7 str. EC4113]... MUKF_ECO57 - Chromosome partition protein MukF OS=Escherichia coli O157:H7 GN=mukF PE=3 SV=1 gi\|209774770, gi... - pir\|\|E90754 mukF protein [imported] - Escherichia coli (strain O157:H7, substrain RIMD 0509952), gi\|...	807.0	[0..1]	[440..1]
MUKF_ECOHS - Chromosome partition protein MukF OS=Escherichia coli O9:H4 (strain HS) GN=mukF PE=3 SV=1	806.0	[0..1]	[440..1]
MUKF_SHIB3 - Chromosome partition protein MukF OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=muk...	806.0	[0..1]	[440..1]
gi\|77979222 - gi\|77979222\|ref\|ZP_00834642.1\| COG3006: Uncharacterized protein involved in chromosome partitioning ...	804.0	[0..1]	[440..1]

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Predicted Domain #1

Region A:
Residues: [1-290]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEFSQTVPE LVAWARKNDF SISLPVDRLS FLLAVATLNG ERLDGEMSEG ELVDAFRHVS  60
   61 DAFEQTSETI GVRANNAIND MVRQRLLNRF TSEQAEGNAI YRLTPLGIGI TDYYIRQREF 120
  121 STLRLSMQLS IVAGELKRAA DAAEEGGDEF HWHRNVYAPL KYSVAEIFDS IDLTQRLMDE 180
  181 QQQQVKDDIA QLLNKDWRAA ISSCELLLSE TSGTLRELQD TLEAAGDKLQ ANLLRIQDAT 240
  241 MTHDDLHFVD RLVFDLQSKL DRIISWGQQS IDLWIGYDRH VHKFIRTAID

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	154.0
Match:	1t98A
Description:	Crystal Structure of MukF(1-287)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	0.973857124068741	bayes_pls_golite062009
nucleic acid binding	0.802843603200847	bayes_pls_golite062009
DNA binding	0.748163465268532	bayes_pls_golite062009
transcription factor activity	0.102759346011281	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [291-440]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDKNRVFAQR LRQSVQTYFD EPWALTYANA DRLLDMRDEE MALRDEEVTG ELPEDLEYEE  60
   61 FNEIREQLAA IIEEQLAVYK TRQVPLDLGL VVREYLSQYP RARHFDVARI VIDQAVRLGV 120
  121 AQADFTGLPA KWQPINDYGA KVQAHVIDKY

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: