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View Structure Prediction Details

Protein: LEPA_ECOLI
Organism: Escherichia coli
Length: 599 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LEPA_ECOLI.

Description E-value Query
Range		 Subject
Range
LEPA_SHESW - Elongation factor 4 OS=Shewanella sp. (strain W3-18-1) GN=lepA PE=3 SV=1
 604.0 [0..1] [596..1]
LEPA_SHEPC - Elongation factor 4 OS=Shewanella putrefaciens (strain CN-32 / ATCC BAA-453) GN=lepA PE=3 SV=1
gi|124508826, gi... - gi|124547993|ref|ZP_01706789.1| small GTP-binding protein [Shewanella putrefaciens 200], gi|12450882...
 604.0 [0..1] [596..1]
LEPA_SHESA - Elongation factor 4 OS=Shewanella sp. (strain ANA-3) GN=lepA PE=3 SV=1
 603.0 [0..1] [596..1]
LEPA_SHEON - Elongation factor 4 OS=Shewanella oneidensis (strain MR-1) GN=lepA PE=3 SV=1
SO1346 - GTP-binding protein LepA
 603.0 [0..1] [596..1]
LEPA_SHESR - Elongation factor 4 OS=Shewanella sp. (strain MR-7) GN=lepA PE=3 SV=1
LEPA_SHESM - Elongation factor 4 OS=Shewanella sp. (strain MR-4) GN=lepA PE=3 SV=1
 603.0 [0..1] [596..1]
LEPA_ALKEH - Elongation factor 4 OS=Alkalilimnicola ehrlichii (strain ATCC BAA-1101 / DSM 17681 / MLHE-1) GN=lepA...
 603.0 [0..1] [598..29]
LEPA_PSEE4 - Elongation factor 4 OS=Pseudomonas entomophila (strain L48) GN=lepA PE=3 SV=1
gi|95112252 - gi|95112252|emb|CAK16979.1| GTP-binding protein LepA [Pseudomonas entomophila L48]
 603.0 [0..1] [595..4]
LEPA_SHEB9 - Elongation factor 4 OS=Shewanella baltica (strain OS195) GN=lepA PE=3 SV=1
LEPA_SHEB2 - Elongation factor 4 OS=Shewanella baltica (strain OS223) GN=lepA PE=3 SV=1
 603.0 [0..1] [596..1]
LEPA_SHEB8 - Elongation factor 4 OS=Shewanella baltica (strain OS185) GN=lepA PE=3 SV=1
LEPA_SHEB5 - Elongation factor 4 OS=Shewanella baltica (strain OS155 / ATCC BAA-1091) GN=lepA PE=3 SV=1
 602.0 [0..1] [596..1]
gi|107100228 - gi|107100228|ref|ZP_01364146.1| hypothetical protein PaerPA_01001251 [Pseudomonas aeruginosa PACS2]
LEPA_PSEAB - Elongation factor 4 OS=Pseudomonas aeruginosa (strain UCBPP-PA14) GN=lepA PE=3 SV=1
LEPA_PSEAE - GTP-binding protein lepA OS=Pseudomonas aeruginosa GN=lepA PE=3 SV=1
LEPA_PSEA8 - Elongation factor 4 OS=Pseudomonas aeruginosa (strain LESB58) GN=lepA PE=3 SV=1
LEPA_PSEAE - Elongation factor 4 OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) ...
 601.0 [0..1] [595..4]

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Predicted Domain #1
Region A:
Residues: [1-599] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKNIRNFSII AHIDHGKSTL SDRIIQICGG LSDREMEAQV LDSMDLERER GITIKAQSVT  60
   61 LDYKASDGET YQLNFIDTPG HVDFSYEVSR SLAACEGALL VVDAGQGVEA QTLANCYTAM 120
  121 EMDLEVVPVL NKIDLPAADP ERVAEEIEDI VGIDATDAVR CSAKTGVGVQ DVLERLVRDI 180
  181 PPPEGDPEGP LQALIIDSWF DNYLGVVSLI RIKNGTLRKG DKVKVMSTGQ TYNADRLGIF 240
  241 TPKQVDRTEL KCGEVGWLVC AIKDIHGAPV GDTLTLARNP AEKALPGFKK VKPQVYAGLF 300
  301 PVSSDDYEAF RDALGKLSLN DASLFYEPES SSALGFGFRC GFLGLLHMEI IQERLEREYD 360
  361 LDLITTAPTV VYEVETTSRE VIYVDSPSKL PAVNNIYELR EPIAECHMLL PQAYLGNVIT 420
  421 LCVEKRGVQT NMVYHGNQVA LTYEIPMAEV VLDFFDRLKS TSRGYASLDY NFKRFQASDM 480
  481 VRVDVLINGE RVDALALITH RDNSQNRGRE LVEKMKDLIP RQQFDIAIQA AIGTHIIARS 540
  541 TVKQLRKNVL AKCYGGDISR KKKLLQKQKE GKKRMKQIGN VELPQEAFLA ILHVGKDNK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 109.0
Match: 1darA
Description: ELONGATION FACTOR G IN COMPLEX WITH GDP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
structural constituent of ribosome 1.36336810177757 bayes_pls_golite062009
catalytic activity 1.24889475603062 bayes_pls_golite062009
translation elongation factor activity 1.09938814618828 bayes_pls_golite062009
structural molecule activity 1.08228539493269 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle