YRC Public Data Repository - Protein Structure Prediction

Protein:	KDPD_ECOLI
Organism:	Escherichia coli
Length:	894 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KDPD_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|209776672, gi... - pir\|\|D85569 hypothetical protein kdpD [imported] - Escherichia coli (strain O157:H7, substrain EDL9... gi\|15800396, gi\|... - gi\|15800396\|ref\|NP_286408.1\| sensor protein KdpD [Escherichia coli O157:H7 EDL933], gi\|12513598\|gb\|A... gi\|13360181, gi\|... - gi\|15829977\|ref\|NP_308750.1\| sensor for high-affinity potassium transport system [Escherichia coli O... gi\|217325999, gi... - gi\|217325999\|ref\|ZP_03442083.1\| sensor protein KdpD [Escherichia coli O157:H7 str. TW14588], gi\|2173... gi\|13360181, gi\|... - gi\|15829977\|ref\|NP_308750.1\| sensor protein KdpD [Escherichia coli O157:H7 str. Sakai], gi\|13360181\|... gi\|208727553, gi... - gi\|208807752\|ref\|ZP_03250089.1\| sensor protein KdpD [Escherichia coli O157:H7 str. EC4206], gi\|20872... gi\|208732365, gi... - gi\|208815717\|ref\|ZP_03256896.1\| sensor protein KdpD [Escherichia coli O157:H7 str. EC4045], gi\|20873... gi\|208737070, gi... - gi\|208822877\|ref\|ZP_03263195.1\| sensor protein KdpD [Escherichia coli O157:H7 str. EC4042], gi\|20873... gi\|254591245, gi... - gi\|254791845\|ref\|YP_003076682.1\| sensory histidine kinase in two-component regulatory system with Kd... gi\|209158961, gi... - gi\|209397561\|ref\|YP_002269321.1\| sensor protein KdpD [Escherichia coli O157:H7 str. EC4115], gi\|2091... gi\|189002898, gi... - gi\|189002898\|gb\|EDU71884.1\| sensor protein KdpD [Escherichia coli O157:H7 str. EC4076], gi\|168779178... gi\|168786847, gi... - gi\|189372997\|gb\|EDU91413.1\| sensor protein KdpD [Escherichia coli O157:H7 str. EC869], gi\|168786847\|... gi\|189375487, gi... - gi\|189375487\|gb\|EDU93903.1\| sensor protein KdpD [Escherichia coli O157:H7 str. EC508], gi\|168802542\|... gi\|195939039 - gi\|195939039\|ref\|ZP_03084421.1\| sensor protein KdpD [Escherichia coli O157:H7 str. EC4024] gi\|189355775, gi... - gi\|189355775\|gb\|EDU74194.1\| sensor protein KdpD [Escherichia coli O157:H7 str. EC4401], gi\|168757146... gi\|189365153, gi... - gi\|189365153\|gb\|EDU83569.1\| sensor protein KdpD [Escherichia coli O157:H7 str. EC4501], gi\|168764937... gi\|189363335, gi... - gi\|189363335\|gb\|EDU81754.1\| sensor protein KdpD [Escherichia coli O157:H7 str. EC4486], gi\|168767134... gi\|168777019, gi... - gi\|187767646\|gb\|EDU31490.1\| sensor protein KdpD [Escherichia coli O157:H7 str. EC4196], gi\|168777019... gi\|188015208, gi... - gi\|188015208\|gb\|EDU53330.1\| sensor protein KdpD [Escherichia coli O157:H7 str. EC4113], gi\|168750625...	769.0	[0..1]	[894..1]
gi\|188486960, gi... - gi\|75511149\|ref\|ZP_00733867.1\| COG2205: Osmosensitive K+ channel histidine kinase [Escherichia coli ...	768.0	[0..1]	[894..1]
gi\|194421805, gi... - gi\|83585368\|ref\|ZP_00924015.1\| COG2205: Osmosensitive K+ channel histidine kinase [Escherichia coli ... gi\|251784185, gi... - gi\|251784185\|ref\|YP_002998489.1\| hypothetical protein B21_00643 [Escherichia coli BL21], gi\|24237645... gi\|253325375, gi... - gi\|253774331\|ref\|YP_003037162.1\| Osmosensitive K channel His kinase sensor [Escherichia coli BL21(DE...	767.0	[0..1]	[894..1]
gi\|73854697, gi\|... - gi\|74311220\|ref\|YP_309639.1\| sensor protein KdpD [Shigella sonnei Ss046], gi\|73854697\|gb\|AAZ87404.1\|...	766.0	[0..1]	[894..1]
gi\|192956021, gi... - gi\|75234521\|ref\|ZP_00718868.1\| COG2205: Osmosensitive K+ channel histidine kinase [Escherichia coli ... gi\|75229667, gi\|... - gi\|75229667\|ref\|ZP_00716204.1\| COG2205: Osmosensitive K+ channel histidine kinase [Escherichia coli ...	766.0	[0..1]	[894..1]
gi\|192926841, gi... - gi\|75256408\|ref\|ZP_00728066.1\| COG2205: Osmosensitive K+ channel histidine kinase [Escherichia coli ... gi\|194429082, gi... - gi\|75209735\|ref\|ZP_00709943.1\| COG2205: Osmosensitive K+ channel histidine kinase [Escherichia coli ...	766.0	[0..1]	[894..1]
gi\|26246670, gi\|... - gi\|26246670\|ref\|NP_752710.1\| sensor protein KdpD [Escherichia coli CFT073], gi\|26107069\|gb\|AAN79253....	766.0	[0..1]	[894..2]
gi\|215485724, gi... - gi\|215485724\|ref\|YP_002328155.1\| sensor protein KdpD [Escherichia coli O127:H6 str. E2348/69], gi\|21... gi\|190905661, gi... - gi\|75237376\|ref\|ZP_00721418.1\| COG2205: Osmosensitive K+ channel histidine kinase [Escherichia coli ...	765.0	[0..1]	[894..1]
gi\|91209737, gi\|... - gi\|91209737\|ref\|YP_539723.1\| sensor protein KdpD [Escherichia coli UTI89], gi\|91071311\|gb\|ABE06192.1... gi\|237707335, gi... - gi\|237707335\|ref\|ZP_04537816.1\| sensor protein KdpD [Escherichia sp. 3_2_53FAA], gi\|226898545\|gb\|EEH...	765.0	[0..1]	[894..2]
gi\|218557621, gi... - gi\|218557621\|ref\|YP_002390534.1\| sensor protein KdpD [Escherichia coli S88], gi\|218364390\|emb\|CAR020... gi\|117622900, gi... - gi\|117622900\|ref\|YP_851813.1\| sensor protein KdpD [Escherichia coli APEC O1], gi\|115512024\|gb\|ABJ000...	764.0	[0..1]	[894..1]

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Predicted Domain #1

Region A:
Residues: [1-257]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNNEPLRPDP DRLLEQTAAP HRGKLKVFFG ACAGVGKTWA MLAEAQRLRA QGLDIVVGVV  60
   61 ETHGRKDTAA MLEGLAVLPL KRQAYRGRHI SEFDLDAALA RRPALILMDE LAHSNAPGSR 120
  121 HPKRWQDIEE LLEAGIDVFT TVNVQHLESL NDVVSGVTGI QVRETVPDPF FDAADDVVLV 180
  181 DLPPDDLRQR LKEGKVYIAG QAERAIEHFF RKGNLIALRE LALRRTADRV DEQMRAWRGH 240
  241 PGEEKVWHTR DAILLCI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	87.522879
Match:	2r8rA
Description:	No description for 2r8rA was found.

Predicted Domain #2

Region A:
Residues: [258-643]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GHNTGSEKLV RAAARLASRL GSVWHAVYVE TPALHRLPEK KRRAILSALR LAQELGAETA  60
   61 TLSDPAEEKA VVRYAREHNL GKIILGRPAS RRWWRRETFA DRLARIAPDL DQVLVALDEP 120
  121 PARTINNAPD NRSFKDKWRV QIQGCVVAAA LCAVITLIAM QWLMAFDAAN LVMLYLLGVV 180
  181 VVALFYGRWP SVVATVINVV SFDLFFIAPR GTLAVSDVQY LLTFAVMLTV GLVIGNLTAG 240
  241 VRYQARVARY REQRTRHLYE MSKALAVGRS PQDIAATSEQ FIASTFHARS QVLLPDDNGK 300
  301 LQPLTHPQGM TPWDDAIAQW SFDKGLPAGA GTDTLPGVPY QILPLKSGEK TYGLVVVEPG 360
  361 NLRQLMIPEQ QRLLETFTLL VANALE

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	2.3
Match:	1ykdA
Description:	Crystal Structure of the Tandem GAF Domains from a Cyanobacterial Adenylyl Cyclase: Novel Modes of Ligand-Binding and Dimerization
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [644-894]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RLTLTASEEQ ARMASEREQI RNALLAALSH DLRTPLTVLF GQAEILTLDL ASEGSPHARQ  60
   61 ASEIRQHVLN TTRLVNNLLD MARIQSGGFN LKKEWLTLEE VVGSALQMLE PGLSSPINLS 120
  121 LPEPLTLIHV DGPLFERVLI NLLENAVKYA GAQAEIGIDA HVEGENLQLD VWDNGPGLPP 180
  181 GQEQTIFDKF ARGNKESAVP GVGLGLAICR AIVDVHGGTI TAFNRPEGGA CFRVTLPQQT 240
  241 APELEEFHED M

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	51.39794
Match:	2c2aA
Description:	Structure of the entire cytoplasmic portion of a sensor histidine kinase protein
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits