YRC Public Data Repository - Protein Structure Prediction

Protein:	ISPA_ECOLI
Organism:	Escherichia coli
Length:	299 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ISPA_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|58201026 - gi\|58201026\|gb\|AAW66658.1\| geranyl diphosphate synthase [Picrorhiza kurrooa]	297.0	[0..2]	[298..79]
gi\|56122554 - gi\|56122554\|gb\|AAV74395.1\| geranylgeranyl diphosphate synthase [Adonis aestivalis var. palaestina]	295.0	[0..2]	[298..72]
gi\|20386366 - gi\|20386366\|gb\|AAM21638.1\|AF492022_1 geranylgeranyl pyrophosphate synthase [Cistus incanus subsp. cr...	294.0	[0..2]	[298..72]
gi\|46241274 - gi\|46241274\|gb\|AAS82860.1\| geranyl diphosphate synthase large subunit [Antirrhinum majus]	292.0	[0..1]	[298..79]
GGPP1_ARATH - Heterodimeric geranylgeranyl pyrophosphate synthase large subunit 1, chloroplastic OS=Arabidopsis th...	291.0	[0..2]	[298..75]
gi\|17352451 - gi\|17352451\|gb\|AAL17614.2\|AF425235_1 geranylgeranyl diphosphate synthase [Abies grandis]	290.0	[0..2]	[298..90]
gi\|9971808 - gi\|9971808\|gb\|AAG10424.1\| GGDP synthase [Tagetes erecta]	290.0	[0..2]	[298..70]
gi\|6277254 - gi\|6277254\|dbj\|BAA86284.1\| geranylgeranyl pyrophosphate synthase [Croton sublyratus]	290.0	[0..2]	[298..76]
GGPPS_SINAL - Geranylgeranyl pyrophosphate synthase, chloroplastic/chromoplastic OS=Sinapis alba GN=GGPS1 PE=1 SV=...	289.0	[0..2]	[298..71]
GGPPS_HEVBR - Geranylgeranyl pyrophosphate synthase, chloroplastic OS=Hevea brasiliensis GN=GGPS PE=1 SV=1	289.0	[0..2]	[298..78]

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Predicted Domain #1

Region A:
Residues: [1-299]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDFPQQLEAC VKQANQALSR FIAPLPFQNT PVVETMQYGA LLGGKRLRPF LVYATGHMFG  60
   61 VSTNTLDAPA AAVECIHAYS LIHDDLPAMD DDDLRRGLPT CHVKFGEANA ILAGDALQTL 120
  121 AFSILSDADM PEVSDRDRIS MISELASASG IAGMCGGQAL DLDAEGKHVP LDALERIHRH 180
  181 KTGALIRAAV RLGALSAGDK GRRALPVLDK YAESIGLAFQ VQDDILDVVG DTATLGKRQG 240
  241 ADQQLGKSTY PALLGLEQAR KKARDLIDDA RQSLKQLAEQ SLDTSALEAL ADYIIQRNK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	74.69897
Match:	2forA
Description:	Crystal Structure of the Shigella flexneri Farnesyl Pyrophosphate Synthase Complex with an Isopentenyl Pyrophosphate
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits