YRC Public Data Repository - Protein Structure Prediction

Protein:	ILVH_ECOLI
Organism:	Escherichia coli
Length:	163 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ILVH_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|222054606, gi... - gi\|222054606\|ref\|YP_002536968.1\| acetolactate synthase, small subunit [Geobacter sp. FRC-32], gi\|221...	224.0	[0..1]	[163..1]
gi\|78222475, gi\|... - gi\|78222475\|ref\|YP_384222.1\| acetolactate synthase 3 regulatory subunit [Geobacter metallireducens G...	223.0	[0..1]	[163..1]
gi\|71741371, gi\|... - gi\|71838145\|ref\|ZP_00677906.1\| Acetolactate synthase, small subunit [Pelobacter propionicus DSM 2379...	222.0	[0..1]	[163..19]
gi\|148265739, gi... - gi\|88936938\|ref\|ZP_01142530.1\| Acetolactate synthase, small subunit [Geobacter uraniumreducens Rf4],...	222.0	[0..1]	[163..1]
gi\|39997008, gi\|... - gi\|39997008\|ref\|NP_952959.1\| acetolactate synthase 3 regulatory subunit [Geobacter sulfurreducens PC...	222.0	[0..1]	[163..1]
gi\|68178913, gi\|... - gi\|95928696\|ref\|ZP_01311442.1\| acetolactate synthase, small subunit [Desulfuromonas acetoxidans DSM ...	222.0	[0..1]	[163..1]
gi\|78043291, gi\|... - gi\|78043291\|ref\|YP_359376.1\| acetolactate synthase 3 regulatory subunit [Carboxydothermus hydrogenof...	219.0	[0..1]	[161..1]
gi\|88927090, gi\|... - gi\|88949650\|ref\|ZP_01152266.1\| Acetolactate synthase, small subunit [Halorhodospira halophila SL1], ...	219.0	[0..1]	[163..43]
gi\|86556992, gi\|... - gi\|86608450\|ref\|YP_477212.1\| acetolactate synthase 3 regulatory subunit [Synechococcus sp. JA-2-3B'a... gi\|86608450 - gi\|86608450\|ref\|YP_477212.1\| acetolactate synthase, small subunit [Cyanobacteria bacterium Yellowsto...	218.0	[0..1]	[161..1]
gi\|7436727 - gi\|7436727\|pir\|\|S74358 acetolactate synthase ilvN - Synechocystis sp. (strain PCC 6803) gi\|16331478, gi\|... - gi\|16331478\|ref\|NP_442206.1\| acetolactate synthase 3 regulatory subunit [Synechocystis sp. PCC 6803]...	217.0	[0..1]	[161..17]

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Predicted Domain #1

Region A:
Residues: [1-163]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRRILSVLLE NESGALSRVI GLFSQRGYNI ESLTVAPTDD PTLSRMTIQT VGDEKVLEQI  60
   61 EKQLHKLVDV LRVSELGQGA HVEREIMLVK IQASGYGRDE VKRNTEIFRG QIIDVTPSLY 120
  121 TVQLAGTSGK LDAFLASIRD VAKIVEVARS GVVGLSRGDK IMR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	53.69897
Match:	2f1fA
Description:	Crystal structure of the regulatory subunit of acetohydroxyacid synthase isozyme III from E. coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
acetolactate synthase activity	14.1096734416761	bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups	12.4176994384119	bayes_pls_golite062009
catalytic activity	0.645256181736122	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: