YRC Public Data Repository - Protein Structure Prediction

Protein:	IAP_ECOLI
Organism:	Escherichia coli
Length:	345 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for IAP_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|110616164, gi... - gi\|110806616\|ref\|YP_690136.1\| alkaline phosphatase isozyme conversion aminopeptidase [Shigella flexn...	227.0	[0..1]	[345..1]
gi\|209747658, gi... - pir\|\|H85924 alkaline phosphatase isozyme conversion [imported] - Escherichia coli (strain O157:H7, s... gi\|15803270, gi\|... - gi\|15803270\|ref\|NP_289302.1\| alkaline phosphatase isozyme conversion aminopeptidase [Escherichia col... gi\|13363078, gi\|... - gi\|15832861\|ref\|NP_311634.1\| alkaline phosphatase isozyme conversion [Escherichia coli O157:H7], gi\|... gi\|254594093, gi... - gi\|254794693\|ref\|YP_003079530.1\| aminopeptidase in alkaline phosphatase isozyme conversion [Escheric... gi\|209157118, gi... - gi\|209395718\|ref\|YP_002272216.1\| alkaline phosphatase isozyme conversion peptidase [Escherichia coli... gi\|217326730, gi... - gi\|217326730\|ref\|ZP_03442813.1\| alkaline phosphatase isozyme conversion peptidase [Escherichia coli ... gi\|195939466 - gi\|195939466\|ref\|ZP_03084848.1\| alkaline phosphatase isozyme conversion aminopeptidase [Escherichia ... gi\|208729164, gi... - gi\|208809363\|ref\|ZP_03251700.1\| alkaline phosphatase isozyme conversion peptidase [Escherichia coli ... gi\|208734253, gi... - gi\|208812976\|ref\|ZP_03254305.1\| alkaline phosphatase isozyme conversion peptidase [Escherichia coli ... gi\|208740202, gi... - gi\|208820079\|ref\|ZP_03260399.1\| alkaline phosphatase isozyme conversion peptidase [Escherichia coli ... gi\|189362146, gi... - gi\|189362146\|gb\|EDU80565.1\| alkaline phosphatase isozyme conversion peptidase [Escherichia coli O157... gi\|13363078, gi\|... - gi\|15832861\|ref\|NP_311634.1\| alkaline phosphatase isozyme conversion aminopeptidase [Escherichia col... gi\|187769519, gi... - gi\|187769519\|gb\|EDU33363.1\| alkaline phosphatase isozyme conversion peptidase [Escherichia coli O157... gi\|189003278, gi... - gi\|189003278\|gb\|EDU72264.1\| alkaline phosphatase isozyme conversion peptidase [Escherichia coli O157... gi\|189377464, gi... - gi\|189377464\|gb\|EDU95880.1\| alkaline phosphatase isozyme conversion peptidase [Escherichia coli O157... gi\|168749920, gi... - gi\|188015775\|gb\|EDU53897.1\| alkaline phosphatase isozyme conversion peptidase [Escherichia coli O157... gi\|189357336, gi... - gi\|189357336\|gb\|EDU75755.1\| alkaline phosphatase isozyme conversion peptidase [Escherichia coli O157... gi\|168762845, gi... - gi\|189366852\|gb\|EDU85268.1\| alkaline phosphatase isozyme conversion peptidase [Escherichia coli O157...	227.0	[0..1]	[345..1]
gi\|24053172, gi\|... - gi\|24114048\|ref\|NP_708558.1\| alkaline phosphatase isozyme conversion aminopeptidase [Shigella flexne... gi\|30042366, gi\|... - gi\|30064110\|ref\|NP_838281.1\| alkaline phosphatase isozyme conversion aminopeptidase [Shigella flexne...	226.0	[0..1]	[345..1]
gi\|82545174, gi\|... - gi\|82545174\|ref\|YP_409121.1\| alkaline phosphatase isozyme conversion aminopeptidase [Shigella boydii... gi\|215488073, gi... - gi\|215488073\|ref\|YP_002330504.1\| alkaline phosphatase isozyme conversion aminopeptidase [Escherichia... gi\|218362068, gi... - gi\|218555300\|ref\|YP_002388213.1\| alkaline phosphatase isozyme conversion aminopeptidase [Escherichia... gi\|218696351, gi... - gi\|218696351\|ref\|YP_002404018.1\| alkaline phosphatase isozyme conversion aminopeptidase [Escherichia... gi\|188493750, gi... - gi\|75512336\|ref\|ZP_00734888.1\| COG2234: Predicted aminopeptidases [Escherichia coli 53638], gi\|18849... gi\|74313319, gi\|... - gi\|74313319\|ref\|YP_311738.1\| alkaline phosphatase isozyme conversion aminopeptidase [Shigella sonnei... gi\|187430986, gi... - gi\|75176383\|ref\|ZP_00696527.1\| COG2234: Predicted aminopeptidases [Shigella boydii BS512], gi\|187733... gi\|75196728, gi\|... - gi\|75196728\|ref\|ZP_00706798.1\| COG2234: Predicted aminopeptidases [Escherichia coli HS], gi\|15716220...	226.0	[0..1]	[345..1]
gi\|209920196, gi... - gi\|209920196\|ref\|YP_002294280.1\| alkaline phosphatase isozyme conversion aminopeptidase [Escherichia... gi\|75256959, gi\|... - gi\|75256959\|ref\|ZP_00728535.1\| COG2234: Predicted aminopeptidases [Escherichia coli E22], gi\|1930649... gi\|192957012, gi... - gi\|75235648\|ref\|ZP_00719822.1\| COG2234: Predicted aminopeptidases [Escherichia coli E110019], gi\|193... gi\|194427822, gi... - gi\|75210960\|ref\|ZP_00711084.1\| COG2234: Predicted aminopeptidases [Escherichia coli B171], gi\|194427... gi\|157157125, gi... - gi\|75187481\|ref\|ZP_00700748.1\| COG2234: Predicted aminopeptidases [Escherichia coli E24377A], gi\|157...	226.0	[0..1]	[345..1]
gi\|190903198, gi... - gi\|75230036\|ref\|ZP_00716546.1\| COG2234: Predicted aminopeptidases [Escherichia coli B7A], gi\|1911668...	226.0	[0..1]	[345..1]
gi\|190908537, gi... - gi\|75241856\|ref\|ZP_00725675.1\| COG2234: Predicted aminopeptidases [Escherichia coli F11], gi\|1911712... gi\|110344487, gi... - gi\|110642895\|ref\|YP_670625.1\| alkaline phosphatase isozyme conversion aminopeptidase [Escherichia co...	226.0	[0..1]	[345..1]
gi\|242378308, gi... - gi\|251786035\|ref\|YP_003000339.1\| hypothetical protein B21_02568 [Escherichia coli BL21], gi\|24237830... gi\|226839420, gi... - gi\|254037796\|ref\|ZP_04871854.1\| peptidase M28 [Escherichia sp. 1_1_43], gi\|226839420\|gb\|EEH71441.1\| ... gi\|194438983, gi... - gi\|83585588\|ref\|ZP_00924231.1\| COG2234: Predicted aminopeptidases [Escherichia coli 101-1], gi\|19443... gi\|254289445, gi... - gi\|254289445\|ref\|YP_003055193.1\| aminopeptidase in alkaline phosphatase isozyme conversion [Escheric... gi\|169753929, gi... - gi\|170019001\|ref\|YP_001723955.1\| alkaline phosphatase isozyme conversion aminopeptidase [Escherichia... gi\|253974585, gi... - gi\|254162684\|ref\|YP_003045792.1\| aminopeptidase in alkaline phosphatase isozyme conversion [Escheric... gi\|124531498, gi... - gi\|124531498\|ref\|ZP_01701752.1\| peptidase M28 [Escherichia coli B], gi\|124498512\|gb\|EAY46022.1\| pept...	225.0	[0..1]	[345..1]
gi\|227888296, gi... - gi\|227888296\|ref\|ZP_04006101.1\| alkaline phosphatase isozyme conversion aminopeptidase [Escherichia ... gi\|26249159, gi\|... - gi\|26249159\|ref\|NP_755199.1\| alkaline phosphatase isozyme conversion aminopeptidase [Escherichia col...	224.0	[0..1]	[345..1]
gi\|115514112, gi... - gi\|117624988\|ref\|YP_853976.1\| alkaline phosphatase isozyme conversion aminopeptidase [Escherichia co... gi\|226899657, gi... - gi\|237706617\|ref\|ZP_04537098.1\| alkaline phosphatase isozyme conversion protein Iap [Escherichia sp.... gi\|218366515, gi... - gi\|218559746\|ref\|YP_002392659.1\| alkaline phosphatase isozyme conversion aminopeptidase [Escherichia... gi\|91212121, gi\|... - gi\|91212121\|ref\|YP_542107.1\| alkaline phosphatase isozyme conversion aminopeptidase [Escherichia col...	224.0	[0..1]	[345..1]

Back

Predicted Domain #1

Region A:
Residues: [1-345]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFSALRHRTA ALALGVCFIL PVHASSPKPG DFANTQARHI ATFFPGRMTG TPAEMLSADY  60
   61 IRQQFQQMGY RSDIRTFNSR YIYTARDNRK SWHNVTGSTV IAAHEGKAPQ QIIIMAHLDT 120
  121 YAPLSDADAD ANLGGLTLQG MDDNAAGLGV MLELAERLKN TPTEYGIRFV ATSGEEEGKL 180
  181 GAENLLKRMS DTEKKNTLLV INLDNLIVGD KLYFNSGVKT PEAVRKLTRD RALAIARSHG 240
  241 IAATTNPGLN KNYPKGTGCC NDAEIFDKAG IAVLSVEATN WNLGNKDGYQ QRAKTPAFPA 300
  301 GNSWHDVRLD NHQHIDKALP GRIERRCRDV MRIMLPLVKE LAKAS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	48.0
Match:	1vgyA
Description:	Crystal structure of succinyl diaminopimelate desuccinylase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.47058882098324	bayes_pls_golite062009
hydrolase activity	1.0447800491983	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: