YRC Public Data Repository - Protein Structure Prediction

Protein:	HYPB_ECOLI
Organism:	Escherichia coli
Length:	290 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HYPB_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|24053138, gi\|... - gi\|24114018\|ref\|NP_708528.1\| hydrogenase nickel incorporation protein HypB [Shigella flexneri 2a str... gi\|30064081, gi\|... - gi\|30064081\|ref\|NP_838252.1\| hydrogenase nickel incorporation protein HypB [Shigella flexneri 2a str... gi\|110806646, gi... - gi\|110806646\|ref\|YP_690166.1\| hydrogenase nickel incorporation protein HypB [Shigella flexneri 5 str...	266.0	[0..1]	[290..1]
gi\|75187449, gi\|... - gi\|75187449\|ref\|ZP_00700716.1\| COG0378: Ni2+-binding GTPase involved in regulation of expression and...	264.0	[0..1]	[290..1]
gi\|208808086, gi... - gi\|208808086\|ref\|ZP_03250423.1\| hydrogenase isoenzymes nickel incorporation protein HypB [Escherichi... gi\|208812172, gi... - gi\|208812172\|ref\|ZP_03253501.1\| hydrogenase isoenzymes nickel incorporation protein HypB [Escherichi... gi\|208818708, gi... - gi\|208818708\|ref\|ZP_03259028.1\| hydrogenase isoenzymes nickel incorporation protein HypB [Escherichi... gi\|209158440, gi... - gi\|209397040\|ref\|YP_002272191.1\| hydrogenase isoenzymes nickel incorporation protein HypB [Escherich... gi\|168778711, gi... - gi\|189003631\|gb\|EDU72617.1\| hydrogenase isoenzymes nickel incorporation protein HypB [Escherichia co... gi\|168787984, gi... - gi\|189372151\|gb\|EDU90567.1\| hydrogenase isoenzymes nickel incorporation protein HypB [Escherichia co... gi\|168800191, gi... - gi\|189377494\|gb\|EDU95910.1\| hydrogenase isoenzymes nickel incorporation protein HypB [Escherichia co... gi\|195938479 - gi\|195938479\|ref\|ZP_03083861.1\| hydrogenase nickel incorporation protein HypB [Escherichia coli O157... gi\|189357326, gi... - gi\|189357326\|gb\|EDU75745.1\| hydrogenase isoenzymes nickel incorporation protein HypB [Escherichia co... gi\|168762872, gi... - gi\|189366894\|gb\|EDU85310.1\| hydrogenase isoenzymes nickel incorporation protein HypB [Escherichia co... gi\|189362026, gi... - gi\|189362026\|gb\|EDU80445.1\| hydrogenase isoenzymes nickel incorporation protein HypB [Escherichia co... gi\|187769563, gi... - gi\|187769563\|gb\|EDU33407.1\| hydrogenase isoenzymes nickel incorporation protein HypB [Escherichia co... gi\|188015785, gi... - gi\|188015785\|gb\|EDU53907.1\| hydrogenase isoenzymes nickel incorporation protein HypB [Escherichia co... gi\|25313851, gi\|... - pir\|\|G91076 hydrogenase isoenzyme HypB [imported] - Escherichia coli (strain O157:H7, substrain RIM... gi\|15832837, gi\|... - gi\|15832837\|ref\|NP_311610.1\| HypB [Escherichia coli O157:H7], gi\|13363054\|dbj\|BAB37006.1\| hydrogenas... gi\|15832837, gi\|... - gi\|15832837\|ref\|NP_311610.1\| hydrogenase nickel incorporation protein HypB [Escherichia coli O157:H7... gi\|254794668, gi... - gi\|254794668\|ref\|YP_003079505.1\| GTP hydrolase involved in nickel liganding into hydrogenases [Esche... gi\|217327146, gi... - gi\|217327146\|ref\|ZP_03443229.1\| hydrogenase isoenzymes nickel incorporation protein HypB [Escherichi...	263.0	[0..1]	[290..1]
gi\|83569908, gi\|... - gi\|83569908\|ref\|ZP_00921356.1\| COG0378: Ni2+-binding GTPase involved in regulation of expression and...	263.0	[0..1]	[290..1]
gi\|117624959, gi... - gi\|117624959\|ref\|YP_853947.1\| hydrogenase nickel incorporation protein HypB [Escherichia coli APEC O... gi\|218559717, gi... - gi\|218559717\|ref\|YP_002392630.1\| hydrogenase nickel incorporation protein HypB [Escherichia coli S88... gi\|91073661, gi\|... - gi\|91212087\|ref\|YP_542073.1\| hydrogenase nickel incorporation protein HypB [Escherichia coli UTI89],... gi\|226899689, gi... - gi\|237706649\|ref\|ZP_04537130.1\| hydrogenase nickel incorporation protein HypB [Escherichia sp. 3_2_5...	263.0	[0..1]	[290..1]
gi\|41776 - gi\|41776\|emb\|CAA38413.1\| hydrogenase isoenzyme hypB [Escherichia coli]	263.0	[0..1]	[290..1]
gi\|25313849 - pir\|\|G85921 hypothetical protein hypB [imported] - Escherichia coli (strain O157:H7, substrain EDL9... gi\|12517179, gi\|... - gi\|15803245\|ref\|NP_289277.1\| hydrogenase nickel incorporation protein HypB [Escherichia coli O157:H7...	262.0	[0..1]	[290..1]
gi\|81242241, gi\|... - gi\|82778093\|ref\|YP_404442.1\| hydrogenase nickel incorporation protein HypB [Shigella dysenteriae Sd1...	262.0	[0..1]	[290..1]
gi\|62128991, gi\|... - gi\|62181358\|ref\|YP_217775.1\| hydrogenase nickel incorporation protein HypB [Salmonella enterica subs...	261.0	[0..1]	[290..1]
gi\|50120173, gi\|... - gi\|50120173\|ref\|YP_049340.1\| hydrogenase nickel incorporation protein HypB [Pectobacterium atrosepti...	258.0	[0..1]	[287..1]

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Predicted Domain #1

Region A:
Residues: [1-63]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCTTCGCGEG NLYIEGDEHN PHSAFRSAPF APAARPKMKI TGIKAPEFTP SQTEEGDLHY  60
   61 GHG

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [64-290]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EAGTHAPGMS QRRMLEVEID VLDKNNRLAE RNRARFAARK QLVLNLVSSP GSGKTTLLTE  60
   61 TLMRLKDSVP CAVIEGDQQT VNDAARIRAT GTPAIQVNTG KGCHLDAQMI ADAAPRLPLD 120
  121 DNGILFIENV GNLVCPASFD LGEKHKVAVL SVTEGEDKPL KYPHMFAAAS LMLLNKVDLL 180
  181 PYLNFDVEKC IACAREVNPE IEIILISATS GEGMDQWLNW LETQRCA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	46.0
Match:	2hf8A
Description:	No description for 2hf8A was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits