YRC Public Data Repository - Protein Structure Prediction

Protein:	HEMG_ECOLI
Organism:	Escherichia coli
Length:	181 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HEMG_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|74314361, gi\|... - gi\|74314361\|ref\|YP_312780.1\| protoporphyrinogen oxidase [Shigella sonnei Ss046], gi\|73857838\|gb\|AAZ9...	162.0	[0..1]	[181..1]
gi\|81247611, gi\|... - gi\|82546200\|ref\|YP_410147.1\| protoporphyrinogen oxidase [Shigella boydii Sb227], gi\|81247611\|gb\|ABB6...	162.0	[0..1]	[181..1]
gi\|148250\|gb\|AAA... - o181 [Escherichia coli] gi\|148250 - gi\|148250\|gb\|AAA67647.1\| o181 [Escherichia coli]	160.0	[0..1]	[181..1]
gi\|254039063, gi... - gi\|254039063\|ref\|ZP_04873114.1\| protoporphyrinogen oxidase [Escherichia sp. 1_1_43], gi\|226838754\|gb... gi\|192958571, gi... - gi\|75238298\|ref\|ZP_00722297.1\| COG4635: Flavodoxin [Escherichia coli E110019], gi\|193067951\|ref\|ZP_0... gi\|157156299, gi... - gi\|75188590\|ref\|ZP_00701857.1\| COG4635: Flavodoxin [Escherichia coli E24377A], gi\|157156299\|ref\|YP_0...	160.0	[0..1]	[181..1]
gi\|75237617, gi\|... - gi\|75237617\|ref\|ZP_00721637.1\| COG4635: Flavodoxin [Escherichia coli F11], gi\|191173940\|ref\|ZP_03035... gi\|170519210, gi... - gi\|170681492\|ref\|YP_001746182.1\| protoporphyrinogen oxidase [Escherichia coli SMS-3-5], gi\|170519210... gi\|110345786, gi... - gi\|110644194\|ref\|YP_671924.1\| protoporphyrinogen oxidase [Escherichia coli 536], gi\|110345786\|gb\|ABG... gi\|218358446, gi... - gi\|218550905\|ref\|YP_002384696.1\| protoporphyrinogen oxidase [Escherichia fergusonii ATCC 35469], gi\|... gi\|218434578, gi... - gi\|218707481\|ref\|YP_002415000.1\| protoporphyrinogen oxidase [Escherichia coli UMN026], gi\|218434578\|...	160.0	[0..1]	[181..1]
gi\|110807460, gi... - gi\|110807460\|ref\|YP_690980.1\| protoporphyrinogen oxidase [Shigella flexneri 5 str. 8401], gi\|1106170... gi\|24115144, gi\|... - gi\|24115144\|ref\|NP_709654.1\| protoporphyrinogen oxidase [Shigella flexneri 2a str. 301], gi\|24054418... gi\|30043115, gi\|... - gi\|30064855\|ref\|NP_839026.1\| protoporphyrinogen oxidase [Shigella flexneri 2a str. 2457T], gi\|300431...	160.0	[0..1]	[181..1]
gi\|192926668, gi... - gi\|75256228\|ref\|ZP_00727906.1\| COG4635: Flavodoxin [Escherichia coli E22], gi\|193065701\|ref\|ZP_03046... gi\|75230809, gi\|... - gi\|75230809\|ref\|ZP_00717272.1\| COG4635: Flavodoxin [Escherichia coli B7A], gi\|191166102\|ref\|ZP_03027... gi\|75209525, gi\|... - gi\|75209525\|ref\|ZP_00709746.1\| COG4635: Flavodoxin [Escherichia coli B171], gi\|194429237\|ref\|ZP_0306... gi\|209914586, gi... - gi\|209921327\|ref\|YP_002295411.1\| protoporphyrinogen oxidase [Escherichia coli SE11], gi\|209914586\|db... gi\|218697569, gi... - gi\|218697569\|ref\|YP_002405236.1\| protoporphyrinogen oxidase [Escherichia coli 55989], gi\|218354301\|e...	160.0	[0..1]	[181..1]
gi\|56130096, gi\|... - gi\|56415839\|ref\|YP_152914.1\| protoporphyrinogen oxidase [Salmonella enterica subsp. enterica serovar... gi\|197364769, gi... - gi\|197364769\|ref\|YP_002144406.1\| protoporphyrinogen oxidase [Salmonella enterica subsp. enterica ser...	157.0	[0..1]	[181..1]
gi\|213163434 - gi\|213163434\|ref\|ZP_03349144.1\| protoporphyrinogen oxidase [Salmonella enterica subsp. enterica sero... gi\|213424456 - gi\|213424456\|ref\|ZP_03357265.1\| protoporphyrinogen oxidase [Salmonella enterica subsp. enterica sero... gi\|29143637, gi\|... - gi\|29143637\|ref\|NP_806979.1\| protoporphyrinogen oxidase [Salmonella enterica subsp. enterica serovar... gi\|213585845 - gi\|213585845\|ref\|ZP_03367671.1\| protoporphyrinogen oxidase [Salmonella enterica subsp. enterica sero... gi\|16762148 - gi\|16762148\|ref\|NP_457765.1\| protoporphyrinogen oxidase [Salmonella enterica subsp. enterica serovar... gi\|213609124 - gi\|213609124\|ref\|ZP_03368950.1\| protoporphyrinogen oxidase [Salmonella enterica subsp. enterica sero... gi\|200389144, gi... - gi\|200389144\|ref\|ZP_03215756.1\| protoporphyrinogen oxidase [Salmonella enterica subsp. enterica sero... gi\|205274236, gi... - gi\|205354455\|ref\|YP_002228256.1\| protoporphyrinogen oxidase [Salmonella enterica subsp. enterica ser... gi\|206710989, gi... - gi\|207859186\|ref\|YP_002245837.1\| protoporphyrinogen oxidase [Salmonella enterica subsp. enterica ser... gi\|213022543 - gi\|213022543\|ref\|ZP_03336990.1\| protoporphyrinogen oxidase [Salmonella enterica subsp. enterica sero... gi\|194447642, gi... - gi\|194447642\|ref\|YP_002047996.1\| protoporphyrinogen oxidase [Salmonella enterica subsp. enterica ser... gi\|197213609, gi... - gi\|197249906\|ref\|YP_002148912.1\| protoporphyrinogen oxidase [Salmonella enterica subsp. enterica ser... gi\|197243344, gi... - gi\|197265089\|ref\|ZP_03165163.1\| protoporphyrinogen oxidase [Salmonella enterica subsp. enterica sero... gi\|198245564, gi... - gi\|198245564\|ref\|YP_002217913.1\| protoporphyrinogen oxidase [Salmonella enterica subsp. enterica ser... gi\|161617110, gi... - gi\|161617110\|ref\|YP_001591075.1\| protoporphyrinogen oxidase [Salmonella enterica subsp. enterica ser... gi\|168263121, gi... - gi\|205348196\|gb\|EDZ34827.1\| protoporphyrinogen oxidase [Salmonella enterica subsp. enterica serovar ... gi\|194404440, gi... - gi\|194445777\|ref\|YP_002043215.1\| protoporphyrinogen oxidase [Salmonella enterica subsp. enterica ser... gi\|238912990 - gi\|238912990\|ref\|ZP_04656827.1\| protoporphyrinogen oxidase [Salmonella enterica subsp. enterica sero... gi\|62130086, gi\|... - gi\|62182453\|ref\|YP_218870.1\| protoporphyrinogen oxidase [Salmonella enterica subsp. enterica serovar... gi\|213647211 - gi\|213647211\|ref\|ZP_03377264.1\| protoporphyrinogen oxidase [Salmonella enterica subsp. enterica sero... gi\|16504451, gi\|... - gi\|25359131\|pir\|\|AD0914 protoporphyrinogen oxidase [imported] - Salmonella enterica subsp. enterica ... gi\|213850147 - gi\|213850147\|ref\|ZP_03381045.1\| protoporphyrinogen oxidase [Salmonella enterica subsp. enterica sero... gi\|214002459 - gi\|214002459\|ref\|ZP_03413194.1\| protoporphyrinogen oxidase [Salmonella enterica subsp. enterica sero... gi\|224585801, gi... - gi\|224585801\|ref\|YP_002639600.1\| protoporphyrinogen oxidase [Salmonella enterica subsp. enterica ser...	157.0	[0..1]	[181..1]
HEMG_SALTY - Protoporphyrinogen IX dehydrogenase [menaquinone] OS=Salmonella typhimurium (strain LT2 / SGSC1412 /... lcl\|NC_016856.1_... - [gene=hemG] [protein=protoporphyrinogen oxidase] [protein_id=YP_005240252.1] [location=4208827..4209... HEMG_SALTY - Protoporphyrinogen oxidase OS=Salmonella typhimurium GN=hemG PE=3 SV=1 HEMG_SALTY - Protoporphyrinogen IX dehydrogenase [menaquinone] OS=Salmonella typhimurium GN=hemG PE=3 SV=1	156.0	[0..1]	[181..1]

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Predicted Domain #1

Region A:
Residues: [1-181]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTLILFSTR DGQTREIASY LASELKELGI QADVANVHRI EEPQWENYDR VVIGASIRYG  60
   61 HYHSAFQEFV KKHATRLNSM PSAFYSVNLV ARKPEKRTPQ TNSYARKFLM NSQWRPDRCA 120
  121 VIAGALRYPR YRWYDRFMIK LIMKMSGGET DTRKEVVYTD WEQVANFARE IAHLTDKPTL 180
  181 K

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	34.221849
Match:	1ag9A
Description:	Flavodoxin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.275631658558537	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: