YRC Public Data Repository - Protein Structure Prediction

Protein:	GUAC_ECOLI
Organism:	Escherichia coli
Length:	347 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GUAC_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|82500120, gi\|... - gi\|82500120\|ref\|ZP_00885547.1\| IMP dehydrogenase [Caldicellulosiruptor saccharolyticus DSM 8903], gi...	317.0	[0..1]	[342..141]
gi\|166853413, gi... - gi\|167039173\|ref\|YP_001662158.1\| response regulator receiver protein [Thermoanaerobacter sp. X514], ... gi\|167038115, gi... - gi\|76796702\|ref\|ZP_00779057.1\| IMP dehydrogenase [Thermoanaerobacter ethanolicus ATCC 33223], gi\|765... gi\|241902681, gi... - gi\|241902681\|ref\|ZP_04787413.1\| inosine-5'-monophosphate dehydrogenase [Thermoanaerobacter brockii s...	312.0	[0..1]	[341..139]
IMDH_BACHD - Inosine-5'-monophosphate dehydrogenase OS=Bacillus halodurans GN=guaB PE=3 SV=1 IMDH_BACHD - Inosine-5'-monophosphate dehydrogenase OS=Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FER...	311.0	[0..1]	[342..141]
gi\|114804394, gi... - gi\|114845582\|ref\|ZP_01455967.1\| inosine-5'-monophosphate dehydrogenase [Thermoanaerobacter ethanolic...	308.0	[0..1]	[341..94]
gi\|56418544, gi\|... - gi\|56418544\|ref\|YP_145862.1\| inositol-5-monophosphate dehydrogenase [Geobacillus kaustophilus HTA426... gi\|229328469, gi... - gi\|229500654\|ref\|ZP_04394306.1\| inosine-5'-monophosphate dehydrogenase [Geobacillus sp. Y412MC52], g... gi\|220706074, gi... - gi\|221090011\|ref\|ZP_03559507.1\| inosine-5'-monophosphate dehydrogenase [Geobacillus sp. Y412MC61], g...	307.0	[0..1]	[342..143]
gi\|20807078, gi\|... - gi\|20807078\|ref\|NP_622249.1\| IMP dehydrogenase/GMP reductase [Thermoanaerobacter tengcongensis MB4],... gi\|20807078 - gi\|20807078\|ref\|NP_622249.1\| IMP dehydrogenase/GMP reductase [Thermoanaerobacter tengcongensis MB4]	305.0	[0..1]	[341..139]
gi\|89158560, gi\|... - gi\|89211833\|ref\|ZP_01190168.1\| IMP dehydrogenase [Halothermothrix orenii H 168], gi\|89158560\|gb\|EAR7...	305.0	[0..1]	[342..139]
IMDH_AQUAE - Inosine-5'-monophosphate dehydrogenase OS=Aquifex aeolicus GN=guaB PE=3 SV=1 IMDH_AQUAE - Inosine-5'-monophosphate dehydrogenase OS=Aquifex aeolicus (strain VF5) GN=guaB PE=3 SV=1	305.0	[0..1]	[342..142]
gi\|89203316, gi\|... - gi\|89203316\|ref\|ZP_01181997.1\| IMP dehydrogenase [Bacillus cereus subsp. cytotoxis NVH 391-98], gi\|8...	304.0	[0..1]	[342..143]
gi\|6561887, gi\|1... - gi\|6561887\|dbj\|BAA88235.1\| IMP dehydrogenase [Bacillus cereus], pir\|\|JC7305 IMP dehydrogenase (EC 1....	303.0	[0..1]	[342..143]

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Predicted Domain #1

Region A:
Residues: [1-347]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRIEEDLKLG FKDVLIRPKR STLKSRSDVE LERQFTFKHS GQSWSGVPII AANMDTVGTF  60
   61 SMASALASFD ILTAVHKHYS VEEWQAFINN SSADVLKHVM VSTGTSDADF EKTKQILDLN 120
  121 PALNFVCIDV ANGYSEHFVQ FVAKAREAWP TKTICAGNVV TGEMCEELIL SGADIVKVGI 180
  181 GPGSVCTTRV KTGVGYPQLS AVIECADAAH GLGGMIVSDG GCTTPGDVAK AFGGGADFVM 240
  241 LGGMLAGHEE SGGRIVEENG EKFMLFYGMS SESAMKRHVG GVAEYRAAEG KTVKLPLRGP 300
  301 VENTARDILG GLRSACTYVG ASRLKELTKR TTFIRVQEQE NRIFNNL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	78.39794
Match:	2a7rA
Description:	Crystal structure of human Guanosine Monophosphate reductase 2 (GMPR2)
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits