YRC Public Data Repository - Protein Structure Prediction

Protein:	GSP_ECOLI
Organism:	Escherichia coli
Length:	619 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GSP_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|24053453, gi\|... - ref\|NP_708806.1\| glutathionylspermidine synthetase-amidase [Shigella flexneri 2a str. 301], gb\|AAN4... gi\|110806891, gi... - gi\|110806891\|ref\|YP_690411.1\| bifunctional glutathionylspermidine amidase/glutathionylspermidine syn...	774.0	[0..1]	[619..2]
gi\|168760143, gi... - gi\|189369377\|gb\|EDU87793.1\| glutathionylspermidine amidase/glutathionylspermidine synthase [Escheric... gi\|168753952, gi... - gi\|189358683\|gb\|EDU77102.1\| glutathionylspermidine amidase/glutathionylspermidine synthase [Escheric... gi\|13363345, gi\|... - gi\|15833127\|ref\|NP_311900.1\| glutathionylspermidine synthetase/amidase [Escherichia coli O157:H7], g... gi\|188017946, gi... - gi\|188017946\|gb\|EDU56068.1\| glutathionylspermidine amidase/glutathionylspermidine synthase [Escheric... gi\|209759892, gi... - pir\|\|A85958 glutathionylspermidine synthetase/amidase [imported] - Escherichia coli (strain O157:H7,... gi\|189379619, gi... - gi\|189379619\|gb\|EDU98035.1\| glutathionylspermidine amidase/glutathionylspermidine synthase [Escheric... gi\|15803533, gi\|... - gi\|15803533\|ref\|NP_289566.1\| bifunctional glutathionylspermidine amidase/glutathionylspermidine synt... gi\|168781859, gi... - gi\|189000509\|gb\|EDU69495.1\| glutathionylspermidine amidase/glutathionylspermidine synthase [Escheric... gi\|168773360, gi... - gi\|187770757\|gb\|EDU34601.1\| glutathionylspermidine amidase/glutathionylspermidine synthase [Escheric... gi\|13363345, gi\|... - gi\|15833127\|ref\|NP_311900.1\| bifunctional glutathionylspermidine amidase/glutathionylspermidine synt... gi\|189363867, gi... - gi\|189363867\|gb\|EDU82286.1\| glutathionylspermidine amidase/glutathionylspermidine synthase [Escheric... gi\|254794945, gi... - gi\|254794945\|ref\|YP_003079782.1\| fused glutathionylspermidine amidase, glutathionylspermidine synthe... gi\|208821174, gi... - gi\|208821174\|ref\|ZP_03261494.1\| glutathionylspermidine amidase/glutathionylspermidine synthase [Esch... gi\|208735830, gi... - gi\|208814553\|ref\|ZP_03255882.1\| glutathionylspermidine amidase/glutathionylspermidine synthase [Esch... gi\|208729153, gi... - gi\|208809352\|ref\|ZP_03251689.1\| glutathionylspermidine amidase/glutathionylspermidine synthase [Esch... gi\|195937134 - gi\|195937134\|ref\|ZP_03082516.1\| bifunctional glutathionylspermidine amidase/glutathionylspermidine s... gi\|217327603, gi... - gi\|217327603\|ref\|ZP_03443686.1\| glutathionylspermidine amidase/glutathionylspermidine synthase [Esch... gi\|215266386, gi... - gi\|215488314\|ref\|YP_002330745.1\| bifunctional glutathionylspermidine amidase/glutathionylspermidine ... gi\|209162003, gi... - gi\|209400603\|ref\|YP_002272467.1\| glutathionylspermidine amidase/glutathionylspermidine synthase [Esc...	774.0	[0..1]	[619..1]
gi\|242378544, gi... - gi\|251786271\|ref\|YP_003000575.1\| hypothetical protein B21_02813 [Escherichia coli BL21], gi\|24237854... gi\|188493893, gi... - gi\|75515214\|ref\|ZP_00737398.1\| COG0754: Glutathionylspermidine synthase [Escherichia coli 53638], gi... gi\|253974843, gi... - gi\|254162942\|ref\|YP_003046050.1\| fused glutathionylspermidine amidase/glutathionylspermidine synthet... gi\|157162468, gi... - gi\|75196952\|ref\|ZP_00707022.1\| COG0754: Glutathionylspermidine synthase [Escherichia coli HS], gi\|15... gi\|254289691, gi... - gi\|254289691\|ref\|YP_003055439.1\| fused glutathionylspermidine amidase/glutathionylspermidine synthet...	773.0	[0..1]	[619..1]
gi\|26249556, gi\|... - gi\|26249556\|ref\|NP_755596.1\| bifunctional glutathionylspermidine amidase/glutathionylspermidine synt...	773.0	[0..1]	[619..2]
gi\|190907225, gi... - gi\|75240556\|ref\|ZP_00724484.1\| COG0754: Glutathionylspermidine synthase [Escherichia coli F11], gi\|1...	773.0	[0..1]	[619..1]
gi\|91073976, gi\|... - gi\|91212402\|ref\|YP_542388.1\| bifunctional glutathionylspermidine amidase/glutathionylspermidine synt... gi\|117625294, gi... - gi\|117625294\|ref\|YP_854466.1\| bifunctional glutathionylspermidine amidase/glutathionylspermidine syn... gi\|237706265, gi... - gi\|237706265\|ref\|ZP_04536746.1\| glutathionylspermidine synthase [Escherichia sp. 3_2_53FAA], gi\|2268...	772.0	[0..1]	[619..2]
gi\|110344819, gi... - gi\|110643227\|ref\|YP_670957.1\| bifunctional glutathionylspermidine amidase/glutathionylspermidine syn...	771.0	[0..1]	[619..1]
gi\|197364010, gi... - gi\|197364010\|ref\|YP_002143647.1\| bifunctional glutathionylspermidine amidase/glutathionylspermidine ... gi\|56415081, gi\|... - gi\|56415081\|ref\|YP_152156.1\| bifunctional glutathionylspermidine amidase/glutathionylspermidine synt...	763.0	[0..1]	[618..1]
gi\|213650045 - gi\|213650045\|ref\|ZP_03380098.1\| bifunctional glutathionylspermidine amidase/glutathionylspermidine s... gi\|16766439, gi\|... - gi\|16766439\|ref\|NP_462054.1\| bifunctional glutathionylspermidine amidase/glutathionylspermidine synt... gi\|62129283, gi\|... - gi\|62181650\|ref\|YP_218067.1\| bifunctional glutathionylspermidine amidase/glutathionylspermidine synt... gi\|197243156, gi... - gi\|197264901\|ref\|ZP_03164975.1\| bifunctional glutathionylspermidine synthetase/amidase [Salmonella e... gi\|29143404, gi\|... - gi\|29143404\|ref\|NP_806746.1\| bifunctional glutathionylspermidine amidase/glutathionylspermidine synt... gi\|204928003, gi... - gi\|204928003\|ref\|ZP_03219203.1\| glutathionylspermidine synthase [Salmonella enterica subsp. enterica... gi\|238909939 - gi\|238909939\|ref\|ZP_04653776.1\| bifunctional glutathionylspermidine amidase/glutathionylspermidine s... gi\|213161317 - gi\|213161317\|ref\|ZP_03347027.1\| bifunctional glutathionylspermidine amidase/glutathionylspermidine s... gi\|16504219, gi\|... - gi\|25512118\|pir\|\|AC0884 glutathionylspermidine synthetase/amidase [imported] - Salmonella enterica s... gi\|213424822 - gi\|213424822\|ref\|ZP_03357572.1\| bifunctional glutathionylspermidine amidase/glutathionylspermidine s... gi\|205343467, gi... - gi\|205343467\|gb\|EDZ30231.1\| glutathionylspermidine synthase [Salmonella enterica subsp. enterica ser... gi\|194450040, gi... - gi\|194450040\|ref\|YP_002047134.1\| bifunctional glutathionylspermidine amidase/glutathionylspermidine ... gi\|16761917 - gi\|16761917\|ref\|NP_457534.1\| bifunctional glutathionylspermidine amidase/glutathionylspermidine synt... gi\|194711250, gi... - gi\|194735748\|ref\|YP_002116094.1\| bifunctional glutathionylspermidine synthetase/amidase [Salmonella ... gi\|197212888, gi... - gi\|197249185\|ref\|YP_002148060.1\| glutathionylspermidine synthase [Salmonella enterica subsp. enteric... gi\|167990319, gi... - gi\|205331212\|gb\|EDZ17976.1\| glutathionylspermidine synthase [Salmonella enterica subsp. enterica ser... gi\|168238091, gi... - gi\|197289048\|gb\|EDY28419.1\| chap domain protein [Salmonella enterica subsp. enterica serovar Schwarz... gi\|168242958, gi... - gi\|205337855\|gb\|EDZ24619.1\| glutathionylspermidine synthase [Salmonella enterica subsp. enterica ser... gi\|168262910, gi... - gi\|205348436\|gb\|EDZ35067.1\| glutathionylspermidine synthase [Salmonella enterica subsp. enterica ser... gi\|161365483, gi... - gi\|161616119\|ref\|YP_001590084.1\| bifunctional glutathionylspermidine amidase/glutathionylspermidine ... gi\|205323305, gi... - gi\|205323305\|gb\|EDZ11144.1\| glutathionylspermidine synthase [Salmonella enterica subsp. enterica ser...	761.0	[0..1]	[618..1]
gi\|52306778, gi\|... - gi\|52424726\|ref\|YP_087863.1\| bifunctional glutathionylspermidine amidase/glutathionylspermidine synt...	720.0	[0..1]	[618..4]

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Predicted Domain #1

Region A:
Residues: [1-619]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKGTTSQDA PFGTLLGYAP GGVAIYSSDY SSLDPQEYED DAVFRSYIDD EYMGHKWQCV  60
   61 EFARRFLFLN YGVVFTDVGM AWEIFSLRFL REVVNDNILP LQAFPNGSPR APVAGALLIW 120
  121 DKGGEFKDTG HVAIITQLHG NKVRIAEQNV IHSPLPQGQQ WTRELEMVVE NGCYTLKDTF 180
  181 DDTTILGWMI QTEDTEYSLP QPEIAGELLK ISGARLENKG QFDGKWLDEK DPLQNAYVQA 240
  241 NGQVINQDPY HYYTITESAE QELIKATNEL HLMYLHATDK VLKDDNLLAL FDIPKILWPR 300
  301 LRLSWQRRRH HMITGRMDFC MDERGLKVYE YNADSASCHT EAGLILERWA EQGYKGNGFN 360
  361 PAEGLINELA GAWKHSRARP FVHIMQDKDI EENYHAQFME QALHQAGFET RILRGLDELG 420
  421 WDAAGQLIDG EGRLVNCVWK TWAWETAFDQ IREVSDREFA AVPIRTGHPQ NEVRLIDVLL 480
  481 RPEVLVFEPL WTVIPGNKAI LPILWSLFPH HRYLLDTDFT VNDELVKTGY AVKPIAGRCG 540
  541 SNIDLVSHHE EVLDKTSGKF AEQKNIYQQL WCLPKVDGKY IQVCTFTVGG NYGGTCLRGD 600
  601 ESLVIKKESD IEPLIVVKK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	2io7A
Description:	No description for 2io7A was found.

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.10496770272307	bayes_pls_golite062009
ligase activity	1.06538168486849	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: