YRC Public Data Repository - Protein Structure Prediction

Protein:	GLPC_ECOLI
Organism:	Escherichia coli
Length:	396 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GLPC_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|73856242, gi\|... - gi\|74312765\|ref\|YP_311184.1\| sn-glycerol-3-phosphate dehydrogenase subunit C [Shigella sonnei Ss046]...	319.0	[0..1]	[396..1]
gi\|110615760, gi... - gi\|110806212\|ref\|YP_689732.1\| sn-glycerol-3-phosphate dehydrogenase subunit C [Shigella flexneri 5 s...	318.0	[0..1]	[396..1]
gi\|75177958, gi\|... - gi\|75177958\|ref\|ZP_00698020.1\| COG0247: Fe-S oxidoreductase [Shigella boydii BS512], gi\|187732352\|re... gi\|157067407, gi... - gi\|75196284\|ref\|ZP_00706354.1\| COG0247: Fe-S oxidoreductase [Escherichia coli HS], gi\|157161727\|ref\|... gi\|83588229, gi\|... - gi\|83588229\|ref\|ZP_00926854.1\| COG0247: Fe-S oxidoreductase [Escherichia coli 101-1], gi\|194436139\|r... gi\|251785604, gi... - gi\|251785604\|ref\|YP_002999908.1\| hypothetical protein B21_02128 [Escherichia coli BL21], gi\|24237787... gi\|82544513, gi\|... - gi\|82544513\|ref\|YP_408460.1\| sn-glycerol-3-phosphate dehydrogenase subunit C [Shigella boydii Sb227]... gi\|253974155, gi... - gi\|254162254\|ref\|YP_003045362.1\| sn-glycerol-3-phosphate dehydrogenase (anaerobic), small subunit [E... gi\|253772834, gi... - gi\|254289015\|ref\|YP_003054763.1\| sn-glycerol-3-phosphate dehydrogenase (anaerobic), small subunit [E...	317.0	[0..1]	[396..1]
gi\|115513560, gi... - gi\|117624436\|ref\|YP_853349.1\| sn-glycerol-3-phosphate dehydrogenase subunit C [Escherichia coli APEC... gi\|162138403 - gi\|162138403\|ref\|YP_541521.2\| sn-glycerol-3-phosphate dehydrogenase subunit C [Escherichia coli UTI8... gi\|227835651, gi... - gi\|227887301\|ref\|ZP_04005106.1\| Anaerobic glycerol-3-phosphate dehydrogenase subunit C [Escherichia ... gi\|215265531, gi... - gi\|215487459\|ref\|YP_002329890.1\| sn-glycerol-3-phosphate dehydrogenase subunit C [Escherichia coli O... gi\|75243057, gi\|... - gi\|75243057\|ref\|ZP_00726763.1\| COG0247: Fe-S oxidoreductase [Escherichia coli F11], gi\|191169957\|ref... gi\|161486173 - gi\|161486173\|ref\|NP_754670.2\| sn-glycerol-3-phosphate dehydrogenase subunit C [Escherichia coli CFT0... gi\|218700715, gi... - gi\|218700715\|ref\|YP_002408344.1\| sn-glycerol-3-phosphate dehydrogenase subunit C [Escherichia coli I... gi\|110642450, gi... - gi\|110642450\|ref\|YP_670180.1\| sn-glycerol-3-phosphate dehydrogenase subunit C [Escherichia coli 536]... gi\|218365928, gi... - gi\|218559159\|ref\|YP_002392072.1\| sn-glycerol-3-phosphate dehydrogenase subunit C [Escherichia coli S... gi\|218690405, gi... - gi\|218690405\|ref\|YP_002398617.1\| sn-glycerol-3-phosphate dehydrogenase subunit C [Escherichia coli E...	317.0	[0..1]	[396..1]
gi\|30063677, gi\|... - gi\|30063677\|ref\|NP_837848.1\| sn-glycerol-3-phosphate dehydrogenase subunit C [Shigella flexneri 2a s...	317.0	[0..1]	[396..1]
gi\|82777653, gi\|... - gi\|82777653\|ref\|YP_404002.1\| sn-glycerol-3-phosphate dehydrogenase subunit C [Shigella dysenteriae S...	317.0	[0..1]	[396..1]
gi\|16765613, gi\|... - gi\|16765613\|ref\|NP_461228.1\| sn-glycerol-3-phosphate dehydrogenase subunit C [Salmonella typhimurium... gi\|206709508, gi... - gi\|207857705\|ref\|YP_002244356.1\| sn-glycerol-3-phosphate dehydrogenase subunit C [Salmonella enteric... lcl\|NC_016856.1_... - [gene=glpC] [protein=sn-glycerol-3-phosphate dehydrogenase subunit C] [protein_id=YP_005238357.1] [l... gi\|224467757, gi... - gi\|224583230\|ref\|YP_002637028.1\| anaerobic glycerol-3-phosphate dehydrogenase subunit C [Salmonella ... gi\|197263568, gi... - gi\|197263568\|ref\|ZP_03163642.1\| glycerol-3-phosphate dehydrogenase, anaerobic, C subunit [Salmonella... gi\|204321768, gi... - gi\|204929224\|ref\|ZP_03220367.1\| glycerol-3-phosphate dehydrogenase, anaerobic, C subunit [Salmonella... gi\|194451538, gi... - gi\|194451538\|ref\|YP_002046340.1\| sn-glycerol-3-phosphate dehydrogenase subunit C [Salmonella enteric... gi\|194734477, gi... - gi\|194734477\|ref\|YP_002115356.1\| glycerol-3-phosphate dehydrogenase, anaerobic, C subunit [Salmonell... gi\|168261700, gi... - gi\|205349371\|gb\|EDZ36002.1\| glycerol-3-phosphate dehydrogenase, anaerobic, C subunit [Salmonella ent... gi\|168817982, gi... - gi\|205345149\|gb\|EDZ31913.1\| glycerol-3-phosphate dehydrogenase, anaerobic, C subunit [Salmonella ent... gi\|197289669, gi... - gi\|197289669\|gb\|EDY29032.1\| glycerol-3-phosphate dehydrogenase, anaerobic, C subunit [Salmonella ent... gi\|62180859, gi\|... - gi\|62180859\|ref\|YP_217276.1\| sn-glycerol-3-phosphate dehydrogenase subunit C [Salmonella enterica su... gi\|205338532, gi... - gi\|205338532\|gb\|EDZ25296.1\| glycerol-3-phosphate dehydrogenase, anaerobic, C subunit [Salmonella ent... gi\|205325398, gi... - gi\|205325398\|gb\|EDZ13237.1\| glycerol-3-phosphate dehydrogenase, anaerobic, C subunit [Salmonella ent... gi\|167992620, gi... - gi\|205329200\|gb\|EDZ15964.1\| sn-glycerol-3-phosphate dehydrogenase K-small subunit [Salmonella enteri... gi\|238913495 - gi\|238913495\|ref\|ZP_04657332.1\| sn-glycerol-3-phosphate dehydrogenase subunit C [Salmonella enterica...	317.0	[0..1]	[396..1]
gi\|192931959, gi... - gi\|75259709\|ref\|ZP_00731011.1\| COG0247: Fe-S oxidoreductase [Escherichia coli E22], gi\|193062293\|ref... gi\|192958514, gi... - gi\|75238034\|ref\|ZP_00722039.1\| COG0247: Fe-S oxidoreductase [Escherichia coli E110019], gi\|193068235... gi\|75230368, gi\|... - gi\|75230368\|ref\|ZP_00716858.1\| COG0247: Fe-S oxidoreductase [Escherichia coli B7A], gi\|191166485\|ref... gi\|75211654, gi\|... - gi\|75211654\|ref\|ZP_00711733.1\| COG0247: Fe-S oxidoreductase [Escherichia coli B171], gi\|194427104\|re... gi\|157078449, gi... - gi\|75187032\|ref\|ZP_00700299.1\| COG0247: Fe-S oxidoreductase [Escherichia coli E24377A], gi\|157156419... gi\|209912955, gi... - gi\|209919696\|ref\|YP_002293780.1\| sn-glycerol-3-phosphate dehydrogenase subunit C [Escherichia coli S... gi\|218695849, gi... - gi\|218695849\|ref\|YP_002403516.1\| sn-glycerol-3-phosphate dehydrogenase subunit C [Escherichia coli 5...	317.0	[0..1]	[396..1]
gi\|16503511, gi\|... - gi\|25284102\|pir\|\|AD0792 anaerobic glycerol-3-phosphate dehydrogenase chain C [imported] - Salmonella... gi\|214003133 - gi\|214003133\|ref\|ZP_03413868.1\| sn-glycerol-3-phosphate dehydrogenase subunit C [Salmonella enterica... gi\|29136719, gi\|... - gi\|29141093\|ref\|NP_804435.1\| sn-glycerol-3-phosphate dehydrogenase subunit C [Salmonella enterica su... gi\|213648600 - gi\|213648600\|ref\|ZP_03378653.1\| sn-glycerol-3-phosphate dehydrogenase subunit C [Salmonella enterica... gi\|16761212 - gi\|16761212\|ref\|NP_456829.1\| sn-glycerol-3-phosphate dehydrogenase subunit C [Salmonella enterica su... gi\|213622137 - gi\|213622137\|ref\|ZP_03374920.1\| sn-glycerol-3-phosphate dehydrogenase subunit C [Salmonella enterica...	315.0	[0..1]	[396..1]
gi\|146179 - gi\|146179\|gb\|AAA83866.1\| glycerol-3-phosphate dehydrogenase subunit C	313.0	[0..1]	[396..1]

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Predicted Domain #1

Region A:
Residues: [1-199]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNDTSFENCI KCTVCTTACP VSRVNPGYPG PKQAGPDGER LRLKDGALYD EALKYCINCK  60
   61 RCEVACPSDV KIGDIIQRAR AKYDTTRPSL RNFVLSHTDL MGSVSTPFAP IVNTATSLKP 120
  121 VRQLLDAALK IDHRRTLPKY SFGTFRRWYR SVAAQQAQYK DQVAFFHGCF VNYNHPQLGK 180
  181 DLIKVLNAMG TGVQLLSKE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	11.0
Match:	1b0pA
Description:	Pyruvate-ferredoxin oxidoreductase, PFOR, domain I; Pyruvate-ferredoxin oxidoreductase, PFOR, domains VI; Pyruvate-ferredoxin oxidoreductase, PFOR, domain II; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; Pyruvate-ferredoxin oxidoreductase, PFOR, domain V
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
formate dehydrogenase activity	4.7946737640663	bayes_pls_golite062009
NADH dehydrogenase activity	3.13953145151561	bayes_pls_golite062009
NADH dehydrogenase (ubiquinone) activity	2.76338281383262	bayes_pls_golite062009
NADH dehydrogenase (quinone) activity	2.70037803782769	bayes_pls_golite062009
electron carrier activity	2.45164586846912	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor	2.09041948600744	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	1.80621486978907	bayes_pls_golite062009
4 iron, 4 sulfur cluster binding	1.5619384041388	bayes_pls_golite062009
iron-sulfur cluster binding	1.48723437664337	bayes_pls_golite062009
metal cluster binding	1.48723437664337	bayes_pls_golite062009
oxidoreductase activity	0.660370448422897	bayes_pls_golite062009
catalytic activity	0.488483980994331	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	0.0827182678048914	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [200-286]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KCCGVPLIAN GFTDKARKQA ITNVESIREA VGVKGIPVIA TSSTCTFALR DEYPEVLNVD  60
   61 NKGLRDHIEL ATRWLWRKLD EGKTLPL

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [287-396]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPLPLKVVYH TPCHMEKMGW TLYTLELLRN IPGLELTVLD SQCCGIAGTY GFKKENYPTS  60
   61 QAIGAPLFRQ IEESGADLVV TDCETCKWQI EMSTSLRCEH PITLLAQALA

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	16.537602
Match:	PF02754.7
Description:	No description for PF02754.7 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: