YRC Public Data Repository - Protein Structure Prediction

Protein:	GLPA_ECOLI
Organism:	Escherichia coli
Length:	542 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GLPA_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|59481681, gi\|... - gi\|59713433\|ref\|YP_206208.1\| sn-glycerol-3-phosphate dehydrogenase subunit A [Vibrio fischeri ES114]...	362.0	[0..1]	[540..1]
gi\|52426048, gi\|... - gi\|52426048\|ref\|YP_089185.1\| GlpA protein [Mannheimia succiniciproducens MBEL55E], gi\|52308100\|gb\|AA...	352.0	[0..25]	[540..55]
gi\|191170169, gi... - gi\|75243055\|ref\|ZP_00726761.1\| COG0578: Glycerol-3-phosphate dehydrogenase [Escherichia coli F11], g... gi\|110642448, gi... - gi\|110642448\|ref\|YP_670178.1\| sn-glycerol-3-phosphate dehydrogenase subunit A [Escherichia coli 536]...	352.0	[0..25]	[542..25]
gi\|25284092 - gi\|25284092\|pir\|\|H85863 hypothetical protein glpA [imported] - Escherichia coli (strain O157:H7, su... gi\|12516581, gi\|... - gi\|15802790\|ref\|NP_288817.1\| sn-glycerol-3-phosphate dehydrogenase subunit A [Escherichia coli O157:...	351.0	[0..25]	[542..25]
gi\|146177 - gi\|146177\|gb\|AAA83864.1\| glycerol-3-phosphate dehydrogenase subunit A	351.0	[0..25]	[542..25]
gi\|227835649, gi... - gi\|227887299\|ref\|ZP_04005104.1\| sn-glycerol-3-phosphate dehydrogenase subunit A [Escherichia coli 83... gi\|26109033, gi\|... - gi\|26248628\|ref\|NP_754668.1\| sn-glycerol-3-phosphate dehydrogenase subunit A [Escherichia coli CFT07...	351.0	[0..25]	[542..25]
gi\|82777651, gi\|... - gi\|82777651\|ref\|YP_404000.1\| sn-glycerol-3-phosphate dehydrogenase subunit A [Shigella dysenteriae S...	349.0	[0..25]	[542..25]
gi\|218365926, gi... - gi\|218559157\|ref\|YP_002392070.1\| sn-glycerol-3-phosphate dehydrogenase subunit A [Escherichia coli S... gi\|237704717, gi... - gi\|237704717\|ref\|ZP_04535198.1\| sn-glycerol-3-phosphate dehydrogenase subunit A [Escherichia sp. 3_2... gi\|91073107, gi\|... - gi\|91211533\|ref\|YP_541519.1\| sn-glycerol-3-phosphate dehydrogenase subunit A [Escherichia coli UTI89... gi\|117624434, gi... - gi\|117624434\|ref\|YP_853347.1\| sn-glycerol-3-phosphate dehydrogenase subunit A [Escherichia coli APEC...	349.0	[0..25]	[542..25]
gi\|193062443, gi... - gi\|75259707\|ref\|ZP_00731009.1\| COG0578: Glycerol-3-phosphate dehydrogenase [Escherichia coli E22], g... gi\|194414733, gi... - gi\|75211652\|ref\|ZP_00711731.1\| COG0578: Glycerol-3-phosphate dehydrogenase [Escherichia coli B171], ...	349.0	[0..25]	[542..25]
gi\|33148494, gi\|... - gi\|33152271\|ref\|NP_873624.1\| sn-glycerol-3-phosphate dehydrogenase subunit A [Haemophilus ducreyi 35...	348.0	[0..25]	[538..35]

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Predicted Domain #1

Region A:
Residues: [1-542]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTRDSQSSD VIIIGGGATG AGIARDCALR GLRVILVERH DIATGATGRN HGLLHSGARY  60
   61 AVTDAESARE CISENQILKR IARHCVEPTN GLFITLPEDD LSFQATFIRA CEEAGISAEA 120
  121 IDPQQARIIE PAVNPALIGA VKVPDGTVDP FRLTAANMLD AKEHGAVILT AHEVTGLIRE 180
  181 GATVCGVRVR NHLTGETQAL HAPVVVNAAG IWGQHIAEYA DLRIRMFPAK GSLLIMDHRI 240
  241 NQHVINRCRK PSDADILVPG DTISLIGTTS LRIDYNEIDD NRVTAEEVDI LLREGEKLAP 300
  301 VMAKTRILRA YSGVRPLVAS DDDPSGRNVS RGIVLLDHAE RDGLDGFITI TGGKLMTYRL 360
  361 MAEWATDAVC RKLGNTRPCT TADLALPGSQ EPAEVTLRKV ISLPAPLRGS AVYRHGDRTP 420
  421 AWLSEGRLHR SLVCECEAVT AGEVQYAVEN LNVNSLLDLR RRTRVGMGTC QGELCACRAA 480
  481 GLLQRFNVTT SAQSIEQLST FLNERWKGVQ PIAWGDALRE SEFTRWVYQG LCGLEKEQKD 540
  541 AL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	59.69897
Match:	1pj5A
Description:	Crystal structure of dimethylglycine oxidase of Arthrobacter globiformis in complex with acetate
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
oxidoreductase activity, acting on NADH or NADPH	2.35054457932442	bayes_pls_golite062009
oxidoreductase activity	1.98913563045669	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor	1.14701726867934	bayes_pls_golite062009
catalytic activity	1.03127962968326	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	0.960204355303275	bayes_pls_golite062009
dihydrolipoyl dehydrogenase activity	0.7514316327505	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	0.250749784393819	bayes_pls_golite062009
methyltransferase activity	0.232165512555865	bayes_pls_golite062009
aminomethyltransferase activity	0.159388807851771	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: