YRC Public Data Repository - Protein Structure Prediction

Protein:	GLGA_ECOLI
Organism:	Escherichia coli
Length:	477 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GLGA_ECOLI.

Description	E-value	Query Range	Subject Range
GLGA_MANSM - Glycogen synthase OS=Mannheimia succiniciproducens (strain MBEL55E) GN=glgA PE=3 SV=1	368.0	[0..1]	[476..1]
gi\|145632895, gi... - gi\|145632895\|ref\|ZP_01788628.1\| glycogen synthase [Haemophilus influenzae 3655], gi\|144986551\|gb\|EDJ... GLGA_HAEI8 - Glycogen synthase OS=Haemophilus influenzae (strain 86-028NP) GN=glgA PE=3 SV=1	368.0	[0..1]	[476..1]
GLGA_HAEIN - Glycogen synthase OS=Haemophilus influenzae GN=glgA PE=3 SV=1 GLGA_HAEIN - Glycogen synthase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) GN=glgA PE=3...	368.0	[0..1]	[476..1]
GLGA2_NITOC - Glycogen synthase 2 OS=Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848) GN=glgA2 PE=3 SV=1 gi\|207091072 - gi\|207091072\|gb\|EDZ68343.1\| glycogen/starch synthase, ADP-glucose type subfamily [Nitrosococcus ocea... gi\|254434739, gi... - gi\|254434739\|ref\|ZP_05048247.1\| glycogen/starch synthase, ADP-glucose type subfamily [Nitrosococcus ...	366.0	[0..2]	[476..3]
gi\|53732671 - gi\|53732671\|ref\|ZP_00154895.2\| COG0297: Glycogen synthase [Haemophilus influenzae R2846] GLGA_HAEIE - Glycogen synthase OS=Haemophilus influenzae (strain PittEE) GN=glgA PE=3 SV=1	366.0	[0..1]	[476..1]
gi\|145639045, gi... - gi\|145639045\|ref\|ZP_01794653.1\| glycogen synthase [Haemophilus influenzae PittII], gi\|145272017\|gb\|E... gi\|42631658 - gi\|42631658\|ref\|ZP_00157196.1\| COG0297: Glycogen synthase [Haemophilus influenzae R2866]	366.0	[0..1]	[476..1]
GLGA_SALTY - Glycogen synthase OS=Salmonella typhimurium GN=glgA PE=3 SV=2 GLGA_SALPB - Glycogen synthase OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=glgA PE=3 SV=1 GLGA_SALPA - Glycogen synthase OS=Salmonella paratyphi A GN=glgA PE=3 SV=1 GLGA_SALPA - Glycogen synthase OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=glgA PE=3 SV=1 GLGA_SALTY - Glycogen synthase OS=Salmonella typhimurium GN=glgA PE=3 SV=2 gi\|205338838, gi... - gi\|205338838\|gb\|EDZ25602.1\| starch synthase [Salmonella enterica subsp. enterica serovar Heidelberg ... gi\|168260742, gi... - gi\|205350336\|gb\|EDZ36967.1\| starch synthase [Salmonella enterica subsp. enterica serovar Hadar str. ... gi\|168465191, gi... - gi\|195632314\|gb\|EDX50798.1\| starch synthase [Salmonella enterica subsp. enterica serovar Newport str... GLGA_SALNS - Glycogen synthase OS=Salmonella newport (strain SL254) GN=glgA PE=3 SV=1 gi\|167549255, gi... - gi\|205325827\|gb\|EDZ13666.1\| starch synthase [Salmonella enterica subsp. enterica serovar Saintpaul s... gi\|205330720, gi... - gi\|205330720\|gb\|EDZ17484.1\| starch synthase [Salmonella enterica subsp. enterica serovar 4,[5],12:i:... gi\|168232676, gi... - gi\|205333086\|gb\|EDZ19850.1\| starch synthase [Salmonella enterica subsp. enterica serovar Kentucky st... gi\|197291280, gi... - gi\|197291280\|gb\|EDY30632.1\| starch synthase [Salmonella enterica subsp. enterica serovar Schwarzengr... lcl\|NC_016856.1_... - [gene=glgA] [protein=glycogen synthase] [protein_id=YP_005239740.1] [location=complement(3715078..37... GLGA_SALTY - Glycogen synthase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=glgA PE=3 SV=2 GLGA_SALEP - Glycogen synthase OS=Salmonella enteritidis PT4 (strain P125109) GN=glgA PE=3 SV=1 GLGA_SALPB - Glycogen synthase OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=glgA PE=3 SV=1 gi\|197243618, gi... - gi\|197265363\|ref\|ZP_03165437.1\| starch synthase [Salmonella enterica subsp. enterica serovar Saintpa... GLGA_SALPK - Glycogen synthase OS=Salmonella paratyphi A (strain AKU_12601) GN=glgA PE=3 SV=1 GLGA_SALDC - Glycogen synthase OS=Salmonella dublin (strain CT_02021853) GN=glgA PE=3 SV=1 gi\|204322205, gi... - gi\|204928772\|ref\|ZP_03219971.1\| starch synthase [Salmonella enterica subsp. enterica serovar Javiana... GLGA_SALHS - Glycogen synthase OS=Salmonella heidelberg (strain SL476) GN=glgA PE=3 SV=1 gi\|194469520, gi... - gi\|194469520\|ref\|ZP_03075504.1\| starch synthase [Salmonella enterica subsp. enterica serovar Kentuck... GLGA_SALSV - Glycogen synthase OS=Salmonella schwarzengrund (strain CVM19633) GN=glgA PE=3 SV=1 GLGA_SALA4 - Glycogen synthase OS=Salmonella agona (strain SL483) GN=glgA PE=3 SV=1	365.0	[0..1]	[477..1]
GLGA_SALCH - Glycogen synthase OS=Salmonella choleraesuis (strain SC-B67) GN=glgA PE=3 SV=1 GLGA_SALPC - Glycogen synthase OS=Salmonella paratyphi C (strain RKS4594) GN=glgA PE=3 SV=1 GLGA_SALCH - Glycogen synthase OS=Salmonella choleraesuis GN=glgA PE=3 SV=1 GLGA_SALCH - Glycogen synthase OS=Salmonella choleraesuis GN=glgA PE=3 SV=1	365.0	[0..1]	[477..1]
GLGA_SALTI - Glycogen synthase OS=Salmonella typhi GN=glgA PE=3 SV=1 gi\|214002861 - gi\|214002861\|ref\|ZP_03413596.1\| glycogen synthase [Salmonella enterica subsp. enterica serovar Typhi... gi\|213854988 - gi\|213854988\|ref\|ZP_03383228.1\| glycogen synthase [Salmonella enterica subsp. enterica serovar Typhi... gi\|16762766 - gi\|16762766\|ref\|NP_458383.1\| glycogen synthase [Salmonella enterica subsp. enterica serovar Typhi st... GLGA_SALTI - Glycogen synthase OS=Salmonella typhi GN=glgA PE=3 SV=1 gi\|29139890, gi\|... - gi\|29144253\|ref\|NP_807595.1\| glycogen synthase [Salmonella enterica subsp. enterica serovar Typhi st...	363.0	[0..1]	[477..1]
gi\|77975072 - gi\|77975072\|ref\|ZP_00830609.1\| COG0297: Glycogen synthase [Yersinia frederiksenii ATCC 33641]	363.0	[0..1]	[476..1]

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Predicted Domain #1

Region A:
Residues: [1-477]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQVLHVCSEM FPLLKTGGLA DVIGALPAAQ IADGVDARVL LPAFPDIRRG VTDAQVVSRR  60
   61 DTFAGHITLL FGHYNGVGIY LIDAPHLYDR PGSPYHDTNL FAYTDNVLRF ALLGWVGAEM 120
  121 ASGLDPFWRP DVVHAHDWHA GLAPAYLAAR GRPAKSVFTV HNLAYQGMFY AHHMNDIQLP 180
  181 WSFFNIHGLE FNGQISFLKA GLYYADHITA VSPTYAREIT EPQFAYGMEG LLQQRHREGR 240
  241 LSGVLNGVDE KIWSPETDLL LASRYTRDTL EDKAENKRQL QIAMGLKVDD KVPLFAVVSR 300
  301 LTSQKGLDLV LEALPGLLEQ GGQLALLGAG DPVLQEGFLA AAAEYPGQVG VQIGYHEAFS 360
  361 HRIMGGADVI LVPSRFEPCG LTQLYGLKYG TLPLVRRTGG LADTVSDCSL ENLADGVASG 420
  421 FVFEDSNAWS LLRAIRRAFV LWSRPSLWRF VQRQAMAMDF SWQVAAKSYR ELYYRLK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	87.09691
Match:	1rzuA
Description:	Crystal structure of the glycogen synthase from A. tumefaciens in complex with ADP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
glycogen phosphorylase activity	3.34851380039572	bayes_pls_golite062009
transferase activity, transferring hexosyl groups	3.04530122157712	bayes_pls_golite062009
catalytic activity	3.02192459767177	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	2.94500176353224	bayes_pls_golite062009
phosphorylase activity	2.90311878311075	bayes_pls_golite062009
glycogen (starch) synthase activity	2.05207088363955	bayes_pls_golite062009
glucosyltransferase activity	1.8062586862583	bayes_pls_golite062009
transferase activity	1.67770954408305	bayes_pls_golite062009
UDP-N-acetylglucosamine 2-epimerase activity	1.63103907245982	bayes_pls_golite062009
lipopolysaccharide heptosyltransferase activity	1.555502709955	bayes_pls_golite062009
UDP-glucosyltransferase activity	1.4199532885636	bayes_pls_golite062009
UDP-glycosyltransferase activity	1.30934991061674	bayes_pls_golite062009
starch synthase activity	1.073959209177	bayes_pls_golite062009
racemase and epimerase activity, acting on carbohydrates and derivatives	0.27693350081385	bayes_pls_golite062009
alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity	0.22009679964126	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: