YRC Public Data Repository - Protein Structure Prediction

Protein:	FTSK_ECOLI
Organism:	Escherichia coli
Length:	1329 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FTSK_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|157160413, gi... - gi\|75195078\|ref\|ZP_00705148.1\| COG1674: DNA segregation ATPase FtsK/SpoIIIE and related proteins [Es...	1138.0	[0..1]	[1329..1]
gi\|188496443, gi... - gi\|75512043\|ref\|ZP_00734628.1\| COG1674: DNA segregation ATPase FtsK/SpoIIIE and related proteins [Es...	1138.0	[0..1]	[1329..1]
gi\|1004225 - gi\|1004225\|emb\|CAA90178.1\| FtsK [Escherichia coli]	1137.0	[0..1]	[1329..1]
gi\|242376705, gi... - gi\|251784432\|ref\|YP_002998736.1\| hypothetical protein B21_00901 [Escherichia coli BL21], gi\|24237670... gi\|194438685, gi... - gi\|83585833\|ref\|ZP_00924473.1\| COG1674: DNA segregation ATPase FtsK/SpoIIIE and related proteins [Es... gi\|253972905, gi... - gi\|254161004\|ref\|YP_003044112.1\| DNA-binding membrane protein required for chromosome resolution and... gi\|253325125, gi... - gi\|254287812\|ref\|YP_003053560.1\| DNA-binding membrane protein required for chromosome resolution and...	1129.0	[0..1]	[1329..1]
FTSK_SHIFL - DNA translocase FtsK OS=Shigella flexneri GN=ftsK PE=3 SV=1 gi\|24112265, gi\|... - gi\|24112265\|ref\|NP_706775.1\| DNA translocase FtsK [Shigella flexneri 2a str. 301], gi\|24051117\|gb\|AA...	1129.0	[0..1]	[1329..1]
gi\|30062377, gi\|... - gi\|30062377\|ref\|NP_836548.1\| DNA translocase FtsK [Shigella flexneri 2a str. 2457T], gi\|30040623\|gb\|...	1129.0	[0..1]	[1329..1]
gi\|189366836, gi... - gi\|189366836\|gb\|EDU85252.1\| DNA translocase FtsK [Escherichia coli O157:H7 str. EC4501], gi\|16876297... gi\|168776259, gi... - gi\|187768367\|gb\|EDU32211.1\| DNA translocase FtsK [Escherichia coli O157:H7 str. EC4196], gi\|16877625... gi\|168801428, gi... - gi\|189376428\|gb\|EDU94844.1\| DNA translocase FtsK [Escherichia coli O157:H7 str. EC508], gi\|168801428... gi\|195939553 - gi\|195939553\|ref\|ZP_03084935.1\| DNA translocase FtsK [Escherichia coli O157:H7 str. EC4024] FTSK_ECO57 - DNA translocase FtsK OS=Escherichia coli O157:H7 GN=ftsK PE=3 SV=1 gi\|168752128, gi... - gi\|188013951\|gb\|EDU52073.1\| DNA translocase FtsK [Escherichia coli O157:H7 str. EC4113], gi\|16875212... gi\|168756981, gi... - gi\|189355921\|gb\|EDU74340.1\| DNA translocase FtsK [Escherichia coli O157:H7 str. EC4401], gi\|16875698... gi\|254792090, gi... - gi\|254792090\|ref\|YP_003076927.1\| DNA-binding membrane protein required for chromosome resolution and... gi\|209775056, gi... - pir\|\|G90750 cell division protein [imported] - Escherichia coli (strain O157:H7, substrain RIMD 0509... gi\|15830229, gi\|... - gi\|15830229\|ref\|NP_309002.1\| DNA translocase FtsK [Escherichia coli O157:H7 str. Sakai], gi\|13360434... gi\|208815693, gi... - gi\|208815693\|ref\|ZP_03256872.1\| DNA translocase FtsK [Escherichia coli O157:H7 str. EC4045], gi\|2087... gi\|208822334, gi... - gi\|208822334\|ref\|ZP_03262653.1\| DNA translocase FtsK [Escherichia coli O157:H7 str. EC4042], gi\|2087... gi\|209158255, gi... - gi\|209396855\|ref\|YP_002269563.1\| DNA translocase FtsK [Escherichia coli O157:H7 str. EC4115], gi\|209... gi\|217325224, gi... - gi\|217325224\|ref\|ZP_03441308.1\| DNA translocase FtsK [Escherichia coli O157:H7 str. TW14588], gi\|217...	1126.0	[0..1]	[1329..1]
gi\|190907578, gi... - gi\|75240967\|ref\|ZP_00724856.1\| COG1674: DNA segregation ATPase FtsK/SpoIIIE and related proteins [Es...	1124.0	[0..1]	[1329..1]
gi\|25498516 - gi\|25498516\|pir\|\|E85614 cell division protein ftsK [imported] - Escherichia coli (strain O157:H7, s... gi\|12514052, gi\|... - gi\|15800753\|ref\|NP_286767.1\| DNA translocase FtsK [Escherichia coli O157:H7 EDL933], gi\|12514052\|gb\|...	1124.0	[0..1]	[1329..1]
FTSK_ECOL6 - DNA translocase FtsK OS=Escherichia coli O6 GN=ftsK PE=3 SV=1 gi\|227838895, gi... - gi\|227884143\|ref\|ZP_04001948.1\| DNA translocase FtsK [Escherichia coli 83972], gi\|227838895\|gb\|EEJ49... FTSK_ECOL6 - DNA translocase FtsK OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=ftsK PE=3 SV=...	1123.0	[0..1]	[1329..1]

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Predicted Domain #1

Region A:
Residues: [1-223]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQEYIEDKE VTLTKLSSGR RLLEALLILI VLFAVWLMAA LLSFNPSDPS WSQTAWHEPI  60
   61 HNLGGMPGAW LADTLFFIFG VMAYTIPVII VGGCWFAWRH QSSDEYIDYF AVSLRIIGVL 120
  121 ALILTSCGLA AINADDIWYF ASGGVIGSLL STTLQPLLHS SGGTIALLCV WAAGLTLFTG 180
  181 WSWVTIAEKL GGWILNILTF ASNRTRRDDT WVDEDEYEDD EEY

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.28
Match:	1kqfC
Description:	Formate dehydrogenase N, cytochrome (gamma) subunit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.585723167263354	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [224-422]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDENHGKQHE SRRARILRGA LARRKRLAEK FINPMGRQTD AALFSGKRMD DDEEITYTAR  60
   61 GVAADPDDVL FSGNRATQPE YDEYDPLLNG APITEPVAVA AAATTATQSW AAPVEPVTQT 120
  121 PPVASVDVPP AQPTVAWQPV PGPQTGEPVI APAPEGYPQQ SQYAQPAVQY NEPLQQPVQP 180
  181 QQPYYAPAAE QPAQQPYYA

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [423-727]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PAPEQPVAGN AWQAEEQQST FAPQSTYQTE QTYQQPAAQE PLYQQPQPVE QQPVVEPEPV  60
   61 VEETKPARPP LYYFEEVEEK RAREREQLAA WYQPIPEPVK EPEPIKSSLK APSVAAVPPV 120
  121 EAAAAVSPLA SGVKKATLAT GAAATVAAPV FSLANSGGPR PQVKEGIGPQ LPRPKRIRVP 180
  181 TRRELASYGI KLPSQRAAEE KAREAQRNQY DSGDQYNDDE IDAMQQDELA RQFAQTQQQR 240
  241 YGEQYQHDVP VNAEDADAAA EAELARQFAQ TQQQRYSGEQ PAGANPFSLD DFEFSPMKAL 300
  301 LDDGP

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [728-830]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HEPLFTPIVE PVQQPQQPVA PQQQYQQPQQ PVPPQPQYQQ PQQPVAPQPQ YQQPQQPVAP  60
   61 QQQYQQPQQP VAPQQQYQQP QQPVAPQPQD TLLHPLLMRN GDS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5

Region A:
Residues: [831-1329]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RPLHKPTTPL PSLDLLTPPP SEVEPVDTFA LEQMARLVEA RLADFRIKAD VVNYSPGPVI  60
   61 TRFELNLAPG VKAARISNLS RDLARSLSTV AVRVVEVIPG KPYVGLELPN KKRQTVYLRE 120
  121 VLDNAKFRDN PSPLTVVLGK DIAGEPVVAD LAKMPHLLVA GTTGSGKSVG VNAMILSMLY 180
  181 KAQPEDVRFI MIDPKMLELS VYEGIPHLLT EVVTDMKDAA NALRWCVNEM ERRYKLMSAL 240
  241 GVRNLAGYNE KIAEADRMMR PIPDPYWKPG DSMDAQHPVL KKEPYIVVLV DEFADLMMTV 300
  301 GKKVEELIAR LAQKARAAGI HLVLATQRPS VDVITGLIKA NIPTRIAFTV SSKIDSRTIL 360
  361 DQAGAESLLG MGDMLYSGPN STLPVRVHGA FVRDQEVHAV VQDWKARGRP QYVDGITSDS 420
  421 ESEGGAGGFD GAEELDPLFD QAVQFVTEKR KASISGVQRQ FRIGYNRAAR IIEQMEAQGI 480
  481 VSEQGHNGNR EVLAPPPFD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	2iusA
Description:	No description for 2iusA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: