YRC Public Data Repository - Protein Structure Prediction

Protein:	FRLD_ECOLI
Organism:	Escherichia coli
Length:	261 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FRLD_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|28203058, gi\|... - gi\|28210620\|ref\|NP_781564.1\| ribokinase [Clostridium tetani E88], gi\|28203058\|gb\|AAO35501.1\| ribokin...	216.0	[0..2]	[260..4]
gi\|20515184, gi\|... - gi\|20806728\|ref\|NP_621899.1\| ribokinase family sugar kinase [Thermoanaerobacter tengcongensis MB4], ... gi\|20806728 - gi\|20806728\|ref\|NP_621899.1\| Sugar kinase, ribokinase family [Thermoanaerobacter tengcongensis MB4] gi\|254478103, gi... - gi\|254478103\|ref\|ZP_05091486.1\| ribokinase [Carboxydibrachium pacificum DSM 12653], gi\|223490092\|ref...	213.0	[0..1]	[260..1]
gi\|55670460, gi\|... - gi\|55670461\|pdb\|1VM7\|B Chain B, Crystal Structure Of Ribokinase (Tm0960) From Thermotoga Maritima At...	213.0	[0..4]	[260..17]
gi\|106882307, gi... - gi\|119944129\|ref\|YP_941809.1\| ribokinase [Psychromonas ingrahamii 37], gi\|119862733\|gb\|ABM02210.1\| r...	210.0	[0..1]	[260..1]
gi\|89209817, gi\|... - gi\|89209817\|ref\|ZP_01188211.1\| Ribokinase, bacterial [Halothermothrix orenii H 168], gi\|89160469\|gb\|...	208.0	[0..1]	[260..1]
gi\|242258302, gi... - gi\|242258302\|ref\|ZP_04803121.1\| PfkB domain protein [Thermoanaerobacter sp. X513], gi\|242230185\|gb\|E... gi\|167039768, gi... - gi\|167039768\|ref\|YP_001662753.1\| ribokinase-like domain-containing protein [Thermoanaerobacter sp. X...	204.0	[0..1]	[260..1]
gi\|241903428, gi... - gi\|241903428\|ref\|ZP_04788152.1\| PfkB domain protein [Thermoanaerobacter brockii subsp. finnii Ako-1]... gi\|166855888, gi... - gi\|76796323\|ref\|ZP_00778688.1\| PfkB [Thermoanaerobacter ethanolicus ATCC 33223], gi\|76588360\|gb\|EAO6...	203.0	[0..1]	[260..1]
gi\|134300365, gi... - gi\|88947384\|ref\|ZP_01150379.1\| Ribokinase, bacterial [Desulfotomaculum reducens MI-1], gi\|88923165\|g...	203.0	[0..4]	[260..6]

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Predicted Domain #1

Region A:
Residues: [1-261]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTLATIGDN CVDIYPQLNK AFSGGNAVNV AVYCTRYGIQ PGCITWVGDD DYGTKLKQDL  60
   61 ARMGVDISHV HTKHGVTAQT QVELHDNDRV FGDYTEGVMA DFALSEEDYA WLAQYDIVHA 120
  121 AIWGHAEDAF PQLHAAGKLT AFDFSDKWDS PLWQTLVPHL DFAFASAPQE DETLRLKMKA 180
  181 IVARGAGTVI VTLGENGSIA WDGAQFWRQA PEPVTVIDTM GAGDSFIAGF LCGWSAGMTL 240
  241 PQAIAQGTAC AAKTIQYHGA W

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	55.30103
Match:	1vm7A
Description:	Crystal structure of Ribokinase (TM0960) from Thermotoga maritima at 2.15 A resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.21468720585581	bayes_pls_golite062009
transferase activity	1.02723496131053	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.99166926796598	bayes_pls_golite062009
kinase activity	0.93808159830136	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: