YRC Public Data Repository - Protein Structure Prediction

Protein:	FRLC_ECOLI
Organism:	Escherichia coli
Length:	276 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FRLC_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|146295455, gi... - gi\|82500853\|ref\|ZP_00886246.1\| similar to Sugar phosphate isomerases/epimerases [Caldicellulosirupto...	212.0	[0..1]	[270..1]
gi\|54309442, gi\|... - gi\|54309442\|ref\|YP_130462.1\| putative hydroxypyruvate isomerase [Photobacterium profundum SS9], gi\|4...	201.0	[0..2]	[267..8]
gi\|90413675, gi\|... - gi\|90413675\|ref\|ZP_01221664.1\| putative hydroxypyruvate isomerase [Photobacterium profundum 3TCK], g...	200.0	[0..2]	[267..3]
gi\|84386818, gi\|... - gi\|84386818\|ref\|ZP_00989843.1\| putative hydroxypyruvate isomerase [Vibrio splendidus 12B01], gi\|8437...	195.0	[0..2]	[265..3]
gi\|148546809, gi... - gi\|82739329\|ref\|ZP_00902135.1\| hydroxypyruvate isomerase [Pseudomonas putida F1], gi\|82713577\|gb\|EAP... tr\|I7CAN9\|I7CAN9... - Hydroxypyruvate isomerase OS=Pseudomonas putida (strain DOT-T1E) GN=hyi PE=3 SV=1	193.0	[0..2]	[267..3]
gi\|193068829, gi... - gi\|75236974\|ref\|ZP_00721030.1\| COG1082: Sugar phosphate isomerases/epimerases [Escherichia coli E110...	192.0	[0..1]	[276..1]
gi\|115258188, gi... - gi\|116253540\|ref\|YP_769378.1\| putative hydroxypyruvate isomerase [Rhizobium leguminosarum bv. viciae...	192.0	[0..2]	[264..3]
gi\|95109817 - gi\|95109817\|emb\|CAK14522.1\| hydroxypyruvate isomerase [Pseudomonas entomophila L48] gi\|104780830, gi... - gi\|95109817\|emb\|CAK14522.1\| hydroxypyruvate isomerase [Pseudomonas entomophila L48], gi\|104780830\|re...	192.0	[0..2]	[267..3]
gi\|52420920 - gi\|52420920\|emb\|CAH55799.1\| putative regulatory protein GclR [Escherichia coli]	192.0	[0..2]	[263..3]
gi\|75260338, gi\|... - gi\|75260338\|ref\|ZP_00731606.1\| COG1082: Sugar phosphate isomerases/epimerases [Escherichia coli E22]... gi\|191168404, gi... - gi\|75228413\|ref\|ZP_00715059.1\| COG1082: Sugar phosphate isomerases/epimerases [Escherichia coli B7A]... gi\|194427000, gi... - gi\|75211739\|ref\|ZP_00711803.1\| COG1082: Sugar phosphate isomerases/epimerases [Escherichia coli B171...	192.0	[0..1]	[276..1]

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Predicted Domain #1

Region A:
Residues: [1-276]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTGMFTCGH QRLPIEHAFR DASELGYDGI EIWGGRPHAF APDLKAGGIK QIKALAQTYQ  60
   61 MPIIGYTPET NGYPYNMMLG DEHMRRESLD MIKLAMDMAK EMNAGYTLIS AAHAGYLTPP 120
  121 NVIWGRLAEN LSELCEYAEN IGMDLILEPL TPYESNVVCN ANDVLHALAL VPSPRLFSMV 180
  181 DICAPYVQAE PVMSYFDKLG DKLRHLHIVD SDGASDTHYI PGEGKMPLRE LMRDIIERGY 240
  241 EGYCTVELVT MYMNEPRLYA RQALERFRAL LPEDER

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	44.0
Match:	1qtwA
Description:	Endonuclease IV
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.759697113227958	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: