YRC Public Data Repository - Protein Structure Prediction

Protein:	FLHD_ECOLI
Organism:	Escherichia coli
Length:	116 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FLHD_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|67009939 - gi\|67009939\|dbj\|BAD99452.1\| transcriptional activator [Shigella boydii]	187.0	[0..1]	[116..4]
gi\|67009947, gi\|... - gi\|67009947\|dbj\|BAD99457.1\| transcriptional activator [Shigella boydii], gi\|67009942\|dbj\|BAD99454.1\|... gi\|89108732, gi\|... - gi\|89108732\|ref\|AP_002512.1\| DNA-binding transcriptional dual regulator with FlhC [Escherichia coli ... gi\|67009973, gi\|... - gi\|67009973\|dbj\|BAD99471.1\| transcriptional activator [Shigella dysenteriae], gi\|67009970\|dbj\|BAD994... FLHD_ECOUT - Flagellar transcriptional regulator FlhD OS=Escherichia coli (strain UTI89 / UPEC) GN=flhD PE=3 SV=1 FLHD_SHISS - Flagellar transcriptional regulator FlhD OS=Shigella sonnei (strain Ss046) GN=flhD PE=3 SV=1 FLHD_SHIDS - Flagellar transcriptional regulator FlhD OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=flhD P... FLHD_ECOK1 - Flagellar transcriptional regulator FlhD OS=Escherichia coli O1:K1 / APEC GN=flhD PE=3 SV=1 gi\|67009979 - gi\|67009979\|dbj\|BAD99475.1\| transcriptional activator [Shigella sonnei] gi\|68304086\|gb\|A... - FlhD [Escherichia coli] FLHD_ECO55 - Flagellar transcriptional regulator FlhD OS=Escherichia coli (strain 55989 / EAEC) GN=flhD PE=3 SV=1 gi\|254288740, gi... - gi\|254288740\|ref\|YP_003054488.1\| transcriptional activator FlhD [Escherichia coli BL21(DE3)], gi\|253... FLHD_ECO7I - Flagellar transcriptional regulator FlhD OS=Escherichia coli O7:K1 (strain IAI39 / ExPEC) GN=flhD PE... FLHD_ECOLU - Flagellar transcriptional regulator FlhD OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=... gi\|226900607, gi... - gi\|237705850\|ref\|ZP_04536331.1\| transcriptional activator flhD [Escherichia sp. 3_2_53FAA], gi\|22690... gi\|253973853, gi... - gi\|254161952\|ref\|YP_003045060.1\| transcriptional activator FlhD [Escherichia coli B str. REL606], gi... FLHD_ECOSE - Flagellar transcriptional regulator FlhD OS=Escherichia coli (strain SE11) GN=flhD PE=3 SV=1 FLHD_ECO8A - Flagellar transcriptional regulator FlhD OS=Escherichia coli O8 (strain IAI1) GN=flhD PE=3 SV=1 FLHD_ECO45 - Flagellar transcriptional regulator FlhD OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=flhD PE=... FLHD_ECO81 - Flagellar transcriptional regulator FlhD OS=Escherichia coli O81 (strain ED1a) GN=flhD PE=3 SV=1 gi\|49176166, gi\|... - gi\|49176166\|ref\|NP_416406.3\| transcriptional activator FlhD [Escherichia coli K12], gi\|1788202\|gb\|AA... gi\|73026, gi\|145... - pir\|\|XMECFB flagellar transcription activator flbB - Escherichia coli (strain K-12), gi\|68304086\|g... gi\|26108564, gi\|... - gi\|26248160\|ref\|NP_754200.1\| transcriptional activator FlhD [Escherichia coli CFT073], gi\|26108564\|g... FLHD_ECODH - Flagellar transcriptional regulator FlhD OS=Escherichia coli (strain K12 / DH10B) GN=flhD PE=3 SV=1	187.0	[0..1]	[116..4]
gi\|83585508 - gi\|83585508\|ref\|ZP_00924152.1\| hypothetical protein Ecol1_01003238 [Escherichia coli 101-1]	187.0	[0..1]	[116..1]
gi\|13362070 - gi\|13362070\|dbj\|BAB36025.1\| regulator of flagellar biosynthesis FlhD [Escherichia coli O157:H7 str. ... gi\|13362070 - gi\|13362070\|dbj\|BAB36025.1\| regulator of flagellar biosynthesis FlhD [Escherichia coli O157:H7] gi\|209767206, gi... - pir\|\|F85802 regulator of flagellar biosynthesis FlhD [imported] - Escherichia coli (strain O157:H7, ... gi\|15802304, gi\|... - gi\|15802304\|ref\|NP_288329.1\| transcriptional activator FlhD [Escherichia coli O157:H7 EDL933], gi\|12...	186.0	[0..1]	[116..4]
FLHD_ECO5E - Flagellar transcriptional regulator FlhD OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=flhD ... gi\|208816829, gi... - gi\|208816829\|ref\|ZP_03257949.1\| flagellar transcriptional activator FlhD [Escherichia coli O157:H7 s... gi\|217318239, gi... - gi\|217328892\|ref\|ZP_03444973.1\| flagellar transcriptional activator FlhD [Escherichia coli O157:H7 s... gi\|168801868, gi... - gi\|189376054\|gb\|EDU94470.1\| flagellar transcriptional activator FlhD [Escherichia coli O157:H7 str. ... gi\|189370707, gi... - gi\|189370707\|gb\|EDU89123.1\| flagellar transcriptional activator FlhD [Escherichia coli O157:H7 str. ... gi\|208725175, gi... - gi\|208810659\|ref\|ZP_03252535.1\| flagellar transcriptional activator FlhD [Escherichia coli O157:H7 s... gi\|195939596 - gi\|195939596\|ref\|ZP_03084978.1\| transcriptional activator FlhD [Escherichia coli O157:H7 str. EC4024... gi\|168770879, gi... - gi\|189360271\|gb\|EDU78690.1\| flagellar transcriptional activator FlhD [Escherichia coli O157:H7 str. ... gi\|168762310, gi... - gi\|189367380\|gb\|EDU85796.1\| flagellar transcriptional activator FlhD [Escherichia coli O157:H7 str. ... gi\|188999422, gi... - gi\|188999422\|gb\|EDU68408.1\| flagellar transcriptional activator FlhD [Escherichia coli O157:H7 str. ... gi\|254592916, gi... - gi\|254793516\|ref\|YP_003078353.1\| DNA-binding transcriptional dual regulator with FlhC [Escherichia c... gi\|168776557, gi... - gi\|187768107\|gb\|EDU31951.1\| flagellar transcriptional activator FlhD [Escherichia coli O157:H7 str. ... gi\|168757932, gi... - gi\|189355157\|gb\|EDU73576.1\| flagellar transcriptional activator FlhD [Escherichia coli O157:H7 str. ... gi\|168747923, gi... - gi\|188017517\|gb\|EDU55639.1\| flagellar transcriptional activator FlhD [Escherichia coli O157:H7 str. ... FLHD_ECO57 - Flagellar transcriptional regulator FlhD OS=Escherichia coli O157:H7 GN=flhD PE=3 SV=2 gi\|38704029 - gi\|38704029\|ref\|NP_310629.2\| transcriptional activator FlhD [Escherichia coli O157:H7 str. Sakai]	186.0	[0..1]	[116..1]
FLHD_SHIBS - Flagellar transcriptional regulator FlhD OS=Shigella boydii serotype 4 (strain Sb227) GN=flhD PE=3 S... gi\|67009919, gi\|... - gi\|67009919\|dbj\|BAD99440.1\| transcriptional activator [Shigella flexneri], gi\|67009916\|dbj\|BAD99438.... gi\|67009925, gi\|... - gi\|67009925\|dbj\|BAD99444.1\| transcriptional activator [Shigella boydii], gi\|67009922\|dbj\|BAD99442.1\|...	185.0	[0..1]	[116..4]
gi\|67009928 - gi\|67009928\|dbj\|BAD99446.1\| transcriptional activator [Shigella dysenteriae]	184.0	[0..1]	[116..4]
FLHD_ENTS2 - Flagellar transcriptional regulator FlhD OS=Enterobacter sp. (strain 22) GN=flhD PE=3 SV=1	182.0	[0..1]	[116..1]
gi\|56127413, gi\|... - gi\|56413156\|ref\|YP_150231.1\| transcriptional activator FlhD [Salmonella enterica subsp. enterica ser... gi\|29141434, gi\|... - gi\|29141434\|ref\|NP_804776.1\| transcriptional activator FlhD [Salmonella enterica subsp. enterica ser... gi\|16760874 - gi\|16760874\|ref\|NP_456491.1\| transcriptional activator FlhD [Salmonella enterica subsp. enterica ser... gi\|6045175\|dbj\|B... - FlhD [Salmonella typhimurium], FlhD protein [Salmonella typhimurium] gi\|62128135, gi\|... - gi\|62180502\|ref\|YP_216919.1\| transcriptional activator FlhD [Salmonella enterica subsp. enterica ser... gi\|199601792, gi... - gi\|200389347\|ref\|ZP_03215958.1\| flagellar transcriptional activator FlhD [Salmonella enterica subsp.... gi\|197937516, gi... - gi\|198243000\|ref\|YP_002215157.1\| transcriptional activator FlhD [Salmonella enterica subsp. enterica... gi\|197362082, gi... - gi\|197362082\|ref\|YP_002141719.1\| transcriptional activator FlhD [Salmonella enterica subsp. enterica... gi\|197211843, gi... - gi\|197248140\|ref\|YP_002146095.1\| flagellar transcriptional activator FlhD [Salmonella enterica subsp... gi\|16503171, gi\|... - gi\|25300764\|pir\|\|AI0746 flagellar transcription activator FlhD STY2134 [imported] - Salmonella enter... gi\|224468098, gi... - gi\|224583571\|ref\|YP_002637369.1\| transcriptional activator FlhD [Salmonella enterica subsp. enterica... gi\|16765267, gi\|... - gi\|16765267\|ref\|NP_460882.1\| transcriptional activator FlhD [Salmonella typhimurium LT2], gi\|1642046... gi\|207856554, gi... - gi\|207856554\|ref\|YP_002243205.1\| transcriptional activator FlhD [Salmonella enterica subsp. enterica... gi\|6045175, gi\|2... - gi\|6045175\|dbj\|BAA85314.1\| FlhD protein [Salmonella enterica subsp. enterica serovar Typhimurium], g... gi\|205359818, gi... - gi\|205359818\|ref\|ZP_03224423.1\| flagellar transcriptional activator FlhD [Salmonella enterica subsp.... gi\|17017381 - gi\|17017381\|gb\|AAL33643.1\|AF440760_1 FlhD [Salmonella enterica subsp. enterica serovar Pullorum] gi\|205272153, gi... - gi\|205352372\|ref\|YP_002226173.1\| transcriptional activator FlhD [Salmonella enterica subsp. enterica... lcl\|NC_016856.1_... - [gene=flhD] [protein=transcriptional activator FlhD] [protein_id=YP_005237894.1] [location=complemen...	179.0	[0..1]	[116..4]

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Predicted Domain #1

Region A:
Residues: [1-116]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHTSELLKHI YDINLSYLLL AQRLIVQDKA SAMFRLGINE EMATTLAALT LPQMVKLAET  60
   61 NQLVCHFRFD SHQTITQLTQ DSRVDDLQQI HTGIMLSTRL LNDVNQPEEA LRKKRA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	48.0
Match:	1g8eA
Description:	Flagellar transcriptional activator FlhD
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	1.76728328288819	bayes_pls_golite062009
transcription activator activity	0.41227092363175	bayes_pls_golite062009
transcription repressor activity	0.334304405404029	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: