YRC Public Data Repository - Protein Structure Prediction

Protein:	FABZ_ECOLI
Organism:	Escherichia coli
Length:	151 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FABZ_ECOLI.

Description	E-value	Query Range	Subject Range
FABZ_PSEHT - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Pseudoalteromonas haloplanktis (strain TAC ...	201.0	[0..1]	[149..1]
gi\|90413540, gi\|... - gi\|90413540\|ref\|ZP_01221531.1\| (3R)-hydroxymyristoyl ACP dehydratase [Photobacterium profundum 3TCK]...	200.0	[0..1]	[149..1]
FABZ_PHOPR - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Photobacterium profundum GN=fabZ PE=3 SV=1 FABZ_PHOPR - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Photobacterium profundum (strain SS9) GN=fa...	200.0	[0..1]	[149..1]
gi\|84376882, gi\|... - gi\|84389781\|ref\|ZP_00991333.1\| (3R)-hydroxymyristoyl ACP dehydratase [Vibrio splendidus 12B01], gi\|8...	196.0	[0..1]	[149..1]
FABZ_VIBTL - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Vibrio tasmaniensis (strain LGP32) GN=fabZ ... gi\|86146878, gi\|... - gi\|86146878\|ref\|ZP_01065197.1\| (3R)-hydroxymyristoyl ACP dehydratase [Vibrio sp. MED222], gi\|8583533...	196.0	[0..1]	[149..1]
FABZ_YEREN - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Yersinia enterocolitica GN=fabZ PE=3 SV=2	195.0	[0..1]	[151..1]
gi\|88857966, gi\|... - gi\|88857966\|ref\|ZP_01132608.1\| (3R)-hydroxymyristol acyl carrier protein dehydratase [Pseudoalteromo...	195.0	[0..1]	[149..1]
gi\|89075409, gi\|... - gi\|89075409\|ref\|ZP_01161826.1\| (3R)-hydroxymyristoyl ACP dehydratase [Photobacterium sp. SKA34], gi\|...	195.0	[0..1]	[148..1]
FABZ_VIBFM - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Vibrio fischeri (strain MJ11) GN=fabZ PE=3 ... FABZ_VIBF1 - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Vibrio fischeri (strain ATCC 700601 / ES114...	194.0	[0..1]	[149..1]
FABZ_PECAS - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Pectobacterium atrosepticum (strain SCRI 10... FABZ_ERWCT - (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase OS=Erwinia carotovora subsp. atroseptica GN...	194.0	[0..1]	[151..1]

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Predicted Domain #1

Region A:
Residues: [1-151]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTNTHTLQI EEILELLPHR FPFLLVDRVL DFEEGRFLRA VKNVSVNEPF FQGHFPGKPI  60
   61 FPGVLILEAM AQATGILAFK SVGKLEPGEL YYFAGIDEAR FKRPVVPGDQ MIMEVTFEKT 120
  121 RRGLTRFKGV ALVDGKVVCE ATMMCARSRE A

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	47.69897
Match:	1u1zA
Description:	The Structure of (3R)-hydroxyacyl-ACP dehydratase (FabZ)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
CoA hydrolase activity	1.75530090056705	bayes_pls_golite062009
catalytic activity	1.11649534052993	bayes_pls_golite062009
thiolester hydrolase activity	0.65794221902015	bayes_pls_golite062009
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity	0.57527342054578	bayes_pls_golite062009
3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity	0.57527342054578	bayes_pls_golite062009
acyl-CoA thioesterase activity	0.24094527143225	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: