YRC Public Data Repository - Protein Structure Prediction

Protein:	ETK_ECOLI
Organism:	Escherichia coli
Length:	726 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ETK_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|110615577, gi... - gi\|110806029\|ref\|YP_689549.1\| tyrosine kinase [Shigella flexneri 5 str. 8401], gi\|110615577\|gb\|ABF04...	468.0	[0..1]	[725..1]
gi\|188489603, gi... - gi\|75514090\|ref\|ZP_00736420.1\| COG3206: Uncharacterized protein involved in exopolysaccharide biosyn... gi\|191169635, gi... - gi\|75226902\|ref\|ZP_00713791.1\| COG3206: Uncharacterized protein involved in exopolysaccharide biosyn...	468.0	[0..1]	[725..1]
gi\|157077638, gi... - gi\|75186858\|ref\|ZP_00700125.1\| COG3206: Uncharacterized protein involved in exopolysaccharide biosyn...	468.0	[0..1]	[725..1]
gi\|117624256, gi... - gi\|117624256\|ref\|YP_853169.1\| tyrosine kinase [Escherichia coli APEC O1], gi\|115513380\|gb\|ABJ01455.1... gi\|226900881, gi... - gi\|237704515\|ref\|ZP_04534996.1\| tyrosine kinase [Escherichia sp. 3_2_53FAA], gi\|226900881\|gb\|EEH8714...	467.0	[0..1]	[725..13]
gi\|193062857, gi... - gi\|75259198\|ref\|ZP_00730546.1\| COG3206: Uncharacterized protein involved in exopolysaccharide biosyn...	467.0	[0..1]	[725..1]
gi\|24113444, gi\|... - gi\|24113444\|ref\|NP_707954.1\| hypothetical protein SF2124 [Shigella flexneri 2a str. 301], gi\|2405247... gi\|30063509, gi\|... - gi\|30063509\|ref\|NP_837680.1\| hypothetical protein S2248 [Shigella flexneri 2a str. 2457T], gi\|300417...	467.0	[0..1]	[725..13]
gi\|75177180, gi\|... - gi\|75177180\|ref\|ZP_00697278.1\| COG3206: Uncharacterized protein involved in exopolysaccharide biosyn...	467.0	[0..1]	[725..1]
gi\|26248434, gi\|... - gi\|26248434\|ref\|NP_754474.1\| Tyrosine-protein kinase wzc [Escherichia coli CFT073], gi\|26108839\|gb\|A...	466.0	[0..1]	[725..13]
gi\|189371553, gi... - gi\|189371553\|gb\|EDU89969.1\| tyrosine-protein kinase wzc [Escherichia coli O157:H7 str. EC869], gi\|16... gi\|168799057, gi... - gi\|189378486\|gb\|EDU96902.1\| tyrosine-protein kinase wzc [Escherichia coli O157:H7 str. EC508], gi\|16... gi\|195938253 - gi\|195938253\|ref\|ZP_03083635.1\| tyrosine kinase [Escherichia coli O157:H7 str. EC4024] gi\|208726916, gi... - gi\|208807115\|ref\|ZP_03249452.1\| tyrosine-protein kinase wzc [Escherichia coli O157:H7 str. EC4206], ... gi\|189367827, gi... - gi\|189367827\|gb\|EDU86243.1\| tyrosine-protein kinase wzc [Escherichia coli O157:H7 str. EC4501], gi\|1... gi\|189361220, gi... - gi\|189361220\|gb\|EDU79639.1\| tyrosine-protein kinase wzc [Escherichia coli O157:H7 str. EC4486], gi\|1... gi\|168775490, gi... - gi\|187768942\|gb\|EDU32786.1\| tyrosine-protein kinase wzc [Escherichia coli O157:H7 str. EC4196], gi\|1... gi\|168782345, gi... - gi\|189000118\|gb\|EDU69104.1\| tyrosine-protein kinase wzc [Escherichia coli O157:H7 str. EC4076], gi\|1... gi\|161367581 - gi\|161367581\|ref\|NP_288566.2\| tyrosine kinase [Escherichia coli O157:H7 EDL933] gi\|254793844, gi... - gi\|254793844\|ref\|YP_003078681.1\| protein-tyrosine kinase [Escherichia coli O157:H7 str. TW14359], gi... gi\|168750430, gi... - gi\|188015357\|gb\|EDU53479.1\| tyrosine-protein kinase wzc [Escherichia coli O157:H7 str. EC4113], gi\|1... gi\|189355150, gi... - gi\|189355150\|gb\|EDU73569.1\| tyrosine-protein kinase wzc [Escherichia coli O157:H7 str. EC4401], gi\|1... gi\|38704045 - gi\|38704045\|ref\|NP_310892.2\| tyrosine kinase [Escherichia coli O157:H7 str. Sakai] WZC_ECO57 - Tyrosine-protein kinase wzc OS=Escherichia coli O157:H7 GN=wzc PE=3 SV=2 gi\|208730761, gi... - gi\|208817142\|ref\|ZP_03258234.1\| tyrosine-protein kinase wzc [Escherichia coli O157:H7 str. EC4045], ... gi\|208821986, gi... - gi\|208821986\|ref\|ZP_03262306.1\| tyrosine-protein kinase wzc [Escherichia coli O157:H7 str. EC4042], ... gi\|209396474, gi... - gi\|209396474\|ref\|YP_002271303.1\| tyrosine-protein kinase wzc [Escherichia coli O157:H7 str. EC4115],... gi\|217317464, gi... - gi\|217329696\|ref\|ZP_03445775.1\| tyrosine-protein kinase wzc [Escherichia coli O157:H7 str. TW14588],...	466.0	[0..1]	[725..1]
gi\|73856062, gi\|... - gi\|74312585\|ref\|YP_311004.1\| hypothetical protein SSON_2113 [Shigella sonnei Ss046], gi\|73856062\|gb\|...	466.0	[0..1]	[725..13]

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Predicted Domain #1

Region A:
Residues: [1-81]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTKNMNTPP GSTQENEIDL LRLVGELWDH RKFIISVTAL FTLIAVAYSL LSTPIYQADT  60
   61 LVQVEQKQGN AILSGLSDMI P

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	10.638272
Match:	PF02706.6
Description:	No description for PF02706.6 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [82-412]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSSPESAPEI QLLQSRMILG KTIAELNLRD IVEQKYFPIV GRGWARLTKE KPGELAISWM  60
   61 HIPQLNGQDQ QLTLTVGENG HYTLEGEEFT VNGMVGQRLE KDGVALTIAD IKAKPGTQFV 120
  121 LSQRTELEAI NALQETFTVS ERSKESGMLE LTMTGDDPQL ITRILNSIAN NYLQQNIARQ 180
  181 AAQDSQSLEF LQRQLPEVRS ELDQAEEKLN VYRQQRDSVD LNLEAKAVLE QIVNVDNQLN 240
  241 ELTFREAEIS QLYKKDHPTY RALLEKRQTL EQERKRLNKR VSAMPSTQQE VLRLSRDVEA 300
  301 GRAVYLQLLN RQQELSISKS SAIGNVRIID P

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.09
Match:	2oevA
Description:	No description for 2oevA was found.

Predicted Domain #3

Region A:
Residues: [413-527]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AVTQPQPVKP KKALNVVLGF ILGLFISVGA VLARAMLRRG VEAPEQLEEH GISVYATIPM  60
   61 SEWLDKRTRL RKKNLFSNQQ RHRTKNIPFL AVDNPADSAV EAVRALRTSL HFAMM

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [528-726]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ETENNILMIT GATPDSGKTF VSSTLAAVIA QSDQKVLFID ADLRRGYSHN LFTVSNEHGL  60
   61 SEYLAGKDEL NKVIQHFGKG GFDVITRGQV PPNPSELLMR DRMRQLLEWA NDHYDLVIVD 120
  121 TPPMLAVSDA AVVGRSVGTS LLVARFGLNT AKEVSLSMQR LEQAGVNIKG AILNGVIKRA 180
  181 STAYSYGYNY YGYSYSEKE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	35.30103
Match:	2ph1A
Description:	No description for 2ph1A was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits