YRC Public Data Repository - Protein Structure Prediction

Protein:	ENTC_ECOLI
Organism:	Escherichia coli
Length:	391 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ENTC_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|39997478, gi\|... - gi\|39997478\|ref\|NP_953429.1\| anthranilate synthase component I [Geobacter sulfurreducens PCA], gi\|39...	461.0	[0..5]	[389..98]
gi\|88936974, gi\|... - gi\|88936974\|ref\|ZP_01142564.1\| Anthranilate synthase component I [Geobacter uraniumreducens Rf4], gi...	459.0	[0..5]	[389..98]
gi\|110599895, gi... - gi\|222056522\|ref\|YP_002538884.1\| anthranilate synthase component I [Geobacter sp. FRC-32], gi\|221565...	457.0	[0..5]	[389..98]
gi\|48845511, gi\|... - gi\|78223698\|ref\|YP_385445.1\| anthranilate synthase, component I [Geobacter metallireducens GS-15], g...	457.0	[0..5]	[389..98]
gi\|118580005, gi... - gi\|71836560\|ref\|ZP_00676328.1\| Anthranilate synthase component I [Pelobacter propionicus DSM 2379], ...	454.0	[0..5]	[390..98]
gi\|69255802, gi\|... - gi\|69255802\|ref\|ZP_00605544.1\| Anthranilate synthase component I [Magnetococcus sp. MC-1], gi\|682481...	453.0	[0..4]	[389..100]
gi\|73660864, gi\|... - gi\|73749148\|ref\|YP_308387.1\| anthranilate synthase component I [Dehalococcoides sp. CBDB1], gi\|73660...	453.0	[0..3]	[389..83]
gi\|88914832, gi\|... - gi\|88932979\|ref\|ZP_01138661.1\| Anthranilate synthase component I [Dehalococcoides sp. BAV1], gi\|8891...	452.0	[0..3]	[389..83]
gi\|57233826, gi\|... - gi\|57233826\|ref\|YP_182181.1\| anthranilate synthase component I [Dehalococcoides ethenogenes 195], gi...	451.0	[0..3]	[389..83]
gi\|77544427, gi\|... - gi\|77918344\|ref\|YP_356159.1\| anthranilate synthase, component I [Pelobacter carbinolicus DSM 2380], ...	450.0	[0..5]	[390..99]

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Predicted Domain #1

Region A:
Residues: [1-391]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDTSLAEEVQ QTMATLAPNR FFFMSPYRSF TTSGCFARFD EPAVNGDSPD SPFQQKLAAL  60
   61 FADAKAQGIK NPVMVGAIPF DPRQPSSLYI PESWQSFSRQ EKQASARRFT RSQSLNVVER 120
  121 QAIPEQTTFE QMVARAAALT ATPQVDKVVL SRLIDITTDA AIDSGVLLER LIAQNPVSYN 180
  181 FHVPLADGGV LLGASPELLL RKDGERFSSI PLAGSARRQP DEVLDREAGN RLLASEKDRH 240
  241 EHELVTQAMK EVLRERSSEL HVPSSPQLIT TPTLWHLATP FEGKANSQEN ALTLACLLHP 300
  301 TPALSGFPHQ AATQVIAELE PFDRELFGGI VGWCDSEGNG EWVVTIRCAK LRENQVRLFA 360
  361 GAGIVPASSP LGEWRETGVK LSTMLNVFGL H

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	113.0
Match:	1k0eA
Description:	P-aminobenzoate synthase component I
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
anthranilate synthase activity	2.85886151642085	bayes_pls_golite062009
catalytic activity	2.48154800529305	bayes_pls_golite062009
oxo-acid-lyase activity	2.3170865622495	bayes_pls_golite062009
carbon-carbon lyase activity	1.61460950208469	bayes_pls_golite062009
4-amino-4-deoxychorismate synthase activity	1.40615180420162	bayes_pls_golite062009
lyase activity	0.151487106592176	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: