YRC Public Data Repository - Protein Structure Prediction

Protein:	ECOT_ECOLI
Organism:	Escherichia coli
Length:	162 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ECOT_ECOLI.

Description	E-value	Query Range	Subject Range
ECOT_ECOL6 - Ecotin OS=Escherichia coli O6 GN=eco PE=3 SV=2 ECOT_ECOL6 - Ecotin OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=eco PE=3 SV=2 ECOT_ECO24 - Ecotin OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=eco PE=3 SV=1 sp\|B7UFM3\|ECOT_ECO27 - Ecotin OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=eco PE=3 SV=1 gi\|75243025, gi\|... - gi\|75243025\|ref\|ZP_00726731.1\| COG4574: Serine protease inhibitor ecotin [Escherichia coli F11], gi\|... gi\|75231453, gi\|... - gi\|75231453\|ref\|ZP_00717822.1\| COG4574: Serine protease inhibitor ecotin [Escherichia coli B7A], gi\|... ECOT_ECOLU - Ecotin OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=eco PE=3 SV=1 ECOT_ECOL5 - Ecotin OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=eco PE=3 SV=1 ECOT_ECOSM - Ecotin OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=eco PE=3 SV=1 ECOT_ECO81 - Ecotin OS=Escherichia coli O81 (strain ED1a) GN=eco PE=3 SV=1 ECOT_ECO55 - Ecotin OS=Escherichia coli (strain 55989 / EAEC) GN=eco PE=3 SV=1 ECOT_ECOSE - Ecotin OS=Escherichia coli (strain SE11) GN=eco PE=3 SV=1 ECOT_ECO27 - Ecotin OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=eco PE=3 SV=1	257.0	[0..1]	[162..1]
gi\|124526378, gi... - gi\|124526378\|ref\|ZP_01698331.1\| proteinase inhibitor I11, ecotin [Escherichia coli B], gi\|124501849\|... gi\|453992 - gi\|453992\|gb\|AAA16410.1\| ecotin (protease inhibitor) [Escherichia coli]	256.0	[0..1]	[162..8]
gi\|227835617, gi... - gi\|227887267\|ref\|ZP_04005072.1\| ecotin precursor [Escherichia coli 83972], gi\|227835617\|gb\|EEJ46083.... gi\|26109001, gi\|... - gi\|26248596\|ref\|NP_754636.1\| ecotin precursor [Escherichia coli CFT073], gi\|26109001\|gb\|AAN81204.1\|A...	256.0	[0..1]	[162..8]
ECOT_ECO57 - Ecotin OS=Escherichia coli O157:H7 GN=eco PE=3 SV=1 gi\|15832352, gi\|... - gi\|15832352\|ref\|NP_311125.1\| ecotin [Escherichia coli O157:H7 str. Sakai], gi\|13362567\|dbj\|BAB36521.... gi\|217327796, gi... - gi\|217327796\|ref\|ZP_03443879.1\| ecotin [Escherichia coli O157:H7 str. TW14588], gi\|217320163\|gb\|EEC2... gi\|208812913, gi... - gi\|208812913\|ref\|ZP_03254242.1\| ecotin [Escherichia coli O157:H7 str. EC4045], gi\|208734190\|gb\|EDZ82... gi\|208726383, gi... - gi\|208806582\|ref\|ZP_03248919.1\| ecotin [Escherichia coli O157:H7 str. EC4206], gi\|208726383\|gb\|EDZ75... ECOT_ECO5E - Ecotin OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=eco PE=3 SV=1 gi\|208739283, gi... - gi\|208819160\|ref\|ZP_03259480.1\| ecotin [Escherichia coli O157:H7 str. EC4042], gi\|208739283\|gb\|EDZ86... gi\|209765696, gi... - pir\|\|D85860 ecotin, a serine proteinase inhibitor [imported] - Escherichia coli (strain O157:H7, sub... gi\|189372950, gi... - gi\|189372950\|gb\|EDU91366.1\| ecotin [Escherichia coli O157:H7 str. EC869], gi\|168787119\|ref\|ZP_028121... gi\|168780062, gi... - gi\|189002110\|gb\|EDU71096.1\| ecotin [Escherichia coli O157:H7 str. EC4076], gi\|168780062\|ref\|ZP_02805... gi\|195935590 - gi\|195935590\|ref\|ZP_03080972.1\| ecotin precursor [Escherichia coli O157:H7 str. EC4024] gi\|12516544, gi\|... - gi\|15802762\|ref\|NP_288789.1\| ecotin precursor [Escherichia coli O157:H7 EDL933], gi\|12516544\|gb\|AAG5... gi\|189375587, gi... - gi\|189375587\|gb\|EDU94003.1\| ecotin [Escherichia coli O157:H7 str. EC508], gi\|168802425\|ref\|ZP_028274... gi\|189365341, gi... - gi\|189365341\|gb\|EDU83757.1\| ecotin [Escherichia coli O157:H7 str. EC4501], gi\|168764705\|ref\|ZP_02789... gi\|189357670, gi... - gi\|189357670\|gb\|EDU76089.1\| ecotin [Escherichia coli O157:H7 str. EC4401], gi\|168754960\|ref\|ZP_02779... gi\|168773069, gi... - gi\|187771038\|gb\|EDU34882.1\| ecotin [Escherichia coli O157:H7 str. EC4196], gi\|168773069\|ref\|ZP_02798... gi\|189362775, gi... - gi\|189362775\|gb\|EDU81194.1\| ecotin [Escherichia coli O157:H7 str. EC4486], gi\|168767833\|ref\|ZP_02792... gi\|168749616, gi... - gi\|188016092\|gb\|EDU54214.1\| ecotin [Escherichia coli O157:H7 str. EC4113], gi\|168749616\|ref\|ZP_02774... gi\|254593508, gi... - gi\|254794108\|ref\|YP_003078945.1\| ecotin, a serine protease inhibitor [Escherichia coli O157:H7 str. ...	256.0	[0..1]	[162..1]
ECOT_SHIB3 - Ecotin OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=eco PE=3 SV=1 gi\|194434228, gi... - gi\|194434228\|ref\|ZP_03066495.1\| ecotin [Shigella dysenteriae 1012], gi\|194417557\|gb\|EDX33659.1\| ecot... gi\|192958516, gi... - gi\|75238003\|ref\|ZP_00722008.1\| COG4574: Serine protease inhibitor ecotin [Escherichia coli E110019],... ECOT_SHIBS - Ecotin OS=Shigella boydii serotype 4 (strain Sb227) GN=eco PE=3 SV=1	256.0	[0..1]	[162..1]
gi\|91073075, gi\|... - gi\|91211501\|ref\|YP_541487.1\| ecotin precursor [Escherichia coli UTI89], gi\|91073075\|gb\|ABE07956.1\| e...	255.0	[0..1]	[162..8]
ECOT_SHISS - Ecotin OS=Shigella sonnei (strain Ss046) GN=eco PE=3 SV=1	254.0	[0..1]	[162..1]
ECOT_SHIF8 - Ecotin OS=Shigella flexneri serotype 5b (strain 8401) GN=eco PE=3 SV=1 ECOT_SHIFL - Ecotin OS=Shigella flexneri GN=eco PE=3 SV=2 gi\|30041902, gi\|... - gi\|30063649\|ref\|NP_837820.1\| ecotin precursor [Shigella flexneri 2a str. 2457T], gi\|30041902\|gb\|AAP1... gi\|56480066, gi\|... - gi\|56480066\|ref\|NP_708105.2\| ecotin precursor [Shigella flexneri 2a str. 301], gi\|56383617\|gb\|AAN438...	253.0	[0..1]	[162..1]
ECOT_SALCH - Ecotin OS=Salmonella choleraesuis GN=eco PE=3 SV=1 ECOT_SALCH - Ecotin OS=Salmonella choleraesuis (strain SC-B67) GN=eco PE=3 SV=1 ECOT_SALCH - Ecotin OS=Salmonella choleraesuis GN=eco PE=3 SV=1	241.0	[0..3]	[162..1]
gi\|21959886, gi\|... - gi\|22126854\|ref\|NP_670277.1\| ecotin precursor [Yersinia pestis KIM], gi\|21959886\|gb\|AAM86528.1\|AE013...	232.0	[0..2]	[162..22]

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Predicted Domain #1

Region A:
Residues: [1-162]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTILPAVLF AAFATTSAWA AESVQPLEKI APYPQAEKGM KRQVIQLTPQ EDESTLKVEL  60
   61 LIGQTLEVDC NLHRLGGKLE NKTLEGWGYD YYVFDKVSSP VSTMMACPDG KKEKKFVTAY 120
  121 LGDAGMLRYN SKLPIVVYTP DNVDVKYRVW KAEEKIDNAV VR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	61.0
Match:	1azzC
Description:	Ecotin, trypsin inhibitor
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits