YRC Public Data Repository - Protein Structure Prediction

Protein:	DUSB_ECOLI
Organism:	Escherichia coli
Length:	321 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DUSB_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|56552023, gi\|... - gi\|56552023\|ref\|YP_162862.1\| tRNA-dihydrouridine synthase [Zymomonas mobilis subsp. mobilis ZM4], gi...	326.0	[0..1]	[317..16]
gi\|52424587, gi\|... - gi\|52424587\|ref\|YP_087724.1\| hypothetical protein MS0532 [Mannheimia succiniciproducens MBEL55E], gi...	325.0	[0..1]	[320..19]
gi\|255652101 - gi\|255652101\|ref\|ZP_05399003.1\| tRNA-dihydrouridine synthase [Clostridium difficile QCD-37x79] gi\|145952352, gi... - gi\|90572713\|ref\|ZP_01229237.1\| hypothetical protein CdifQ_02003914 [Clostridium difficile QCD-32g58]... gi\|255102766 - gi\|255102766\|ref\|ZP_05331743.1\| tRNA-dihydrouridine synthase [Clostridium difficile QCD-63q42] gi\|255308587 - gi\|255308587\|ref\|ZP_05352758.1\| tRNA-dihydrouridine synthase [Clostridium difficile ATCC 43255] gi\|255316261 - gi\|255316261\|ref\|ZP_05357844.1\| tRNA-dihydrouridine synthase [Clostridium difficile QCD-76w55] gi\|255518922 - gi\|255518922\|ref\|ZP_05386598.1\| tRNA-dihydrouridine synthase [Clostridium difficile QCD-97b34] gi\|254977180 - gi\|254977180\|ref\|ZP_05273652.1\| tRNA-dihydrouridine synthase [Clostridium difficile QCD-66c26] gi\|255094510 - gi\|255094510\|ref\|ZP_05323988.1\| tRNA-dihydrouridine synthase [Clostridium difficile CIP 107932] gi\|115252617, gi... - gi\|126701180\|ref\|YP_001090077.1\| tRNA-dihydrouridine synthase [Clostridium difficile 630], gi\|115252...	325.0	[0..1]	[319..1]
gi\|170717873, gi... - gi\|46156521\|ref\|ZP_00204726.1\| COG0042: tRNA-dihydrouridine synthase [Haemophilus somnus 2336], gi\|1...	323.0	[0..1]	[318..1]
gi\|113460710, gi... - gi\|23467880\|ref\|ZP_00123457.1\| COG0042: tRNA-dihydrouridine synthase [Haemophilus somnus 129PT], gi\|...	321.0	[0..1]	[318..1]
gi\|84376320, gi\|... - gi\|84393068\|ref\|ZP_00991834.1\| NifR3/Smm1 family protein [Vibrio splendidus 12B01], gi\|84376320\|gb\|E...	321.0	[0..1]	[321..1]
DUSB_PASMU - tRNA-dihydrouridine synthase B OS=Pasteurella multocida GN=dusB PE=3 SV=2 DUSB_PASMU - tRNA-dihydrouridine synthase B OS=Pasteurella multocida (strain Pm70) GN=dusB PE=3 SV=2	321.0	[0..1]	[318..1]
gi\|89075353, gi\|... - gi\|89075353\|ref\|ZP_01161775.1\| putative Dihydrouridine synthase [Photobacterium sp. SKA34], gi\|89048... gi\|90581290, gi\|... - gi\|90581290\|ref\|ZP_01237087.1\| putative Dihydrouridine synthase [Vibrio angustum S14], gi\|90437529\|g...	321.0	[0..1]	[321..1]
gi\|88775590, gi\|... - gi\|88793018\|ref\|ZP_01108735.1\| tRNA-dihydrouridine synthase B [Alteromonas macleodii 'Deep ecotype']...	321.0	[0..1]	[320..1]
gi\|12721426, gi\|... - gi\|15602952\|ref\|NP_246024.1\| hypothetical protein PM1087 [Pasteurella multocida subsp. multocida str...	321.0	[0..1]	[318..3]

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Predicted Domain #1

Region A:
Residues: [1-321]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRIGQYQLRN RLIAAPMAGI TDRPFRTLCY EMGAGLTVSE MMSSNPQVWE SDKSRLRMVH  60
   61 IDEPGIRTVQ IAGSDPKEMA DAARINVESG AQIIDINMGC PAKKVNRKLA GSALLQYPDV 120
  121 VKSILTEVVN AVDVPVTLKI RTGWAPEHRN CEEIAQLAED CGIQALTIHG RTRACLFNGE 180
  181 AEYDSIRAVK QKVSIPVIAN GDITDPLKAR AVLDYTGADA LMIGRAAQGR PWIFREIQHY 240
  241 LDTGELLPPL PLAEVKRLLC AHVRELHDFY GPAKGYRIAR KHVSWYLQEH APNDQFRRTF 300
  301 NAIEDASEQL EALEAYFENF A

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	65.0
Match:	1vhnA
Description:	Crystal structure of a putative flavin oxidoreductase with flavin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.94749091175302	bayes_pls_golite062009
tRNA dihydrouridine synthase activity	1.94490879164338	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: