YRC Public Data Repository - Protein Structure Prediction

Protein:	DLHH_ECOLI
Organism:	Escherichia coli
Length:	271 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DLHH_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|24115126, gi\|... - gi\|24115126\|ref\|NP_709636.1\| putative enzyme [Shigella flexneri 2a str. 301], gi\|24054396\|gb\|AAN4534...	200.0	[0..1]	[271..23]
gi\|25499550, gi\|... - gi\|25499550\|pir\|\|F86070 probable enzyme Z5352 [imported] - Escherichia coli (strain O157:H7, substra... gi\|12518707, gi\|... - gi\|15804422\|ref\|NP_290462.1\| putative enzyme [Escherichia coli O157:H7 EDL933], gi\|12518707\|gb\|AAG59... gi\|13364236, gi\|... - gi\|15834014\|ref\|NP_312787.1\| hypothetical protein ECs4760 [Escherichia coli O157:H7], gi\|13364236\|db... gi\|13364236, gi\|... - gi\|15834014\|ref\|NP_312787.1\| hypothetical protein ECs4760 [Escherichia coli O157:H7 str. Sakai], gi\|...	199.0	[0..1]	[271..23]
gi\|75197713 - gi\|75197713\|ref\|ZP_00707783.1\| COG0412: Dienelactone hydrolase and related enzymes [Escherichia coli...	198.0	[0..1]	[271..19]
gi\|75209543 - gi\|75209543\|ref\|ZP_00709764.1\| COG0412: Dienelactone hydrolase and related enzymes [Escherichia coli... gi\|75188572 - gi\|75188572\|ref\|ZP_00701839.1\| COG0412: Dienelactone hydrolase and related enzymes [Escherichia coli... gi\|75238280 - gi\|75238280\|ref\|ZP_00722279.1\| COG0412: Dienelactone hydrolase and related enzymes [Escherichia coli... gi\|75230791 - gi\|75230791\|ref\|ZP_00717254.1\| COG0412: Dienelactone hydrolase and related enzymes [Escherichia coli...	198.0	[0..1]	[271..19]
gi\|82546183, gi\|... - gi\|82546183\|ref\|YP_410130.1\| putative enzyme [Shigella boydii Sb227], gi\|81247594\|gb\|ABB68302.1\| put...	197.0	[0..1]	[270..23]
gi\|75512615 - gi\|75512615\|ref\|ZP_00735127.1\| COG0412: Dienelactone hydrolase and related enzymes [Escherichia coli...	196.0	[0..1]	[271..19]
gi\|75256246 - gi\|75256246\|ref\|ZP_00727924.1\| COG0412: Dienelactone hydrolase and related enzymes [Escherichia coli...	196.0	[0..1]	[271..19]
gi\|81243137, gi\|... - gi\|82778989\|ref\|YP_405338.1\| putative enzyme [Shigella dysenteriae Sd197], gi\|81243137\|gb\|ABB63847.1...	196.0	[0..1]	[271..19]
gi\|83569334 - gi\|83569334\|ref\|ZP_00920789.1\| COG0412: Dienelactone hydrolase and related enzymes [Shigella dysente...	196.0	[0..1]	[270..19]
gi\|75177796 - gi\|75177796\|ref\|ZP_00697861.1\| COG0412: Dienelactone hydrolase and related enzymes [Shigella boydii ...	194.0	[0..1]	[270..19]

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Predicted Domain #1

Region A:
Residues: [1-271]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATTQQSGFA PAASPLASTI VQTPDDAIVA GFTSIPSQGD NMPAYHARPK QSDGPLPVVI  60
   61 VVQEIFGVHE HIRDICRRLA LEGYLAIAPE LYFREGDPND FADIPTLLSG LVAKVPDSQV 120
  121 LADLDHVASW ASRNGGDVHR LMITGFCWGG RITWLYAAHN PQLKAAVAWY GKLTGDKSLN 180
  181 SPKQPVDIAT DLNAPILGLY GGQDNSIPQE SVETMRQALR AANAKAEIIV YPDAGHAFNA 240
  241 DYRPSYHAAS AEDGWQRMLE WFKQYGGKKS L

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	21.154902
Match:	1dinA
Description:	DIENELACTONE HYDROLASE AT 2.8 ANGSTROMS
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrolase activity	1.58619437002934	bayes_pls_golite062009
catalytic activity	1.39629727416851	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.635759022538529	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: