YRC Public Data Repository - Protein Structure Prediction

Protein:	DEGS_ECOLI
Organism:	Escherichia coli
Length:	355 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DEGS_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|59712832, gi\|... - gi\|59712832\|ref\|YP_205608.1\| serine endoprotease DegP (protease Do), periplasmic [Vibrio fischeri ES...	289.0	[0..1]	[353..1]
gi\|218691517, gi... - gi\|218691517\|ref\|YP_002399729.1\| serine endoprotease [Escherichia coli ED1a], gi\|218429081\|emb\|CAR10... gi\|215488543, gi... - gi\|215488543\|ref\|YP_002330974.1\| serine endoprotease [Escherichia coli O127:H6 str. E2348/69], gi\|21... gi\|191173817, gi... - gi\|75237910\|ref\|ZP_00721921.1\| COG0265: Trypsin-like serine proteases, typically periplasmic, contai... gi\|26249816, gi\|... - gi\|26249816\|ref\|NP_755856.1\| serine endoprotease [Escherichia coli CFT073], gi\|26110244\|gb\|AAN82430.... gi\|110345061, gi... - gi\|110643469\|ref\|YP_671199.1\| serine endoprotease [Escherichia coli 536], gi\|110345061\|gb\|ABG71298.1...	289.0	[0..1]	[355..1]
gi\|242378773, gi... - gi\|251786500\|ref\|YP_003000804.1\| hypothetical protein B21_03046 [Escherichia coli BL21], gi\|24237877... gi\|254289922, gi... - gi\|254289922\|ref\|YP_003055670.1\| serine endoprotease, periplasmic [Escherichia coli BL21(DE3)], gi\|2... gi\|218353666, gi... - gi\|218696934\|ref\|YP_002404601.1\| serine endoprotease [Escherichia coli 55989], gi\|218353666\|emb\|CAU9... gi\|253975073, gi... - gi\|254163172\|ref\|YP_003046280.1\| serine endoprotease, periplasmic [Escherichia coli B str. REL606], ... gi\|209920705, gi... - gi\|209920705\|ref\|YP_002294789.1\| serine endoprotease [Escherichia coli SE11], gi\|209913964\|dbj\|BAG79... gi\|194421906, gi... - gi\|83585394\|ref\|ZP_00924040.1\| COG0265: Trypsin-like serine proteases, typically periplasmic, contai... gi\|157157456, gi... - gi\|75188035\|ref\|ZP_00701302.1\| COG0265: Trypsin-like serine proteases, typically periplasmic, contai... gi\|194429143, gi... - gi\|75209672\|ref\|ZP_00709884.1\| COG0265: Trypsin-like serine proteases, typically periplasmic, contai... gi\|24053711, gi\|... - gi\|24114522\|ref\|NP_709032.1\| serine endoprotease [Shigella flexneri 2a str. 301], gi\|24053711\|gb\|AAN... gi\|193065339, gi... - gi\|75256605\|ref\|ZP_00728235.1\| COG0265: Trypsin-like serine proteases, typically periplasmic, contai... gi\|110807097, gi... - gi\|110807097\|ref\|YP_690617.1\| serine endoprotease [Shigella flexneri 5 str. 8401], gi\|110616645\|gb\|A... gi\|30064567, gi\|... - gi\|30064567\|ref\|NP_838738.1\| serine endoprotease [Shigella flexneri 2a str. 2457T], gi\|30042826\|gb\|A... gi\|75511869, gi\|... - gi\|75511869\|ref\|ZP_00734481.1\| COG0265: Trypsin-like serine proteases, typically periplasmic, contai... gi\|194434891, gi... - gi\|194434891\|ref\|ZP_03067137.1\| periplasmic serine peptidase DegS [Shigella dysenteriae 1012], gi\|19...	287.0	[0..1]	[355..1]
gi\|187731547, gi... - gi\|75176079\|ref\|ZP_00696247.1\| COG0265: Trypsin-like serine proteases, typically periplasmic, contai... gi\|82545536, gi\|... - gi\|82545536\|ref\|YP_409483.1\| serine endoprotease [Shigella boydii Sb227], gi\|81246947\|gb\|ABB67655.1\|...	286.0	[0..1]	[355..1]
gi\|36787309, gi\|... - gi\|37527873\|ref\|NP_931218.1\| protease precursor DegQ [Photorhabdus luminescens subsp. laumondii TTO1...	285.0	[0..1]	[354..1]
gi\|25305627 - gi\|25305627\|pir\|\|G85987 trypsin-like proteinase degS (EC 3.4.21.-) - Escherichia coli (strain O157:H... gi\|15803769, gi\|... - gi\|15803769\|ref\|NP_289803.1\| serine endoprotease [Escherichia coli O157:H7 EDL933], gi\|12517856\|gb\|A...	285.0	[0..1]	[355..1]
gi\|90580204, gi\|... - gi\|90580204\|ref\|ZP_01236011.1\| putative DegQ serine protease [Vibrio angustum S14], gi\|90438506\|gb\|E...	282.0	[0..13]	[354..7]
gi\|50119263, gi\|... - gi\|50119263\|ref\|YP_048430.1\| exported protease [Pectobacterium atrosepticum SCRI1043], gi\|49609789\|e...	281.0	[0..1]	[348..1]
gi\|16762108 - gi\|16762108\|ref\|NP_457725.1\| serine endoprotease [Salmonella enterica subsp. enterica serovar Typhi ... gi\|213648052 - gi\|213648052\|ref\|ZP_03378105.1\| serine endoprotease [Salmonella enterica subsp. enterica serovar Typ... gi\|213865023 - gi\|213865023\|ref\|ZP_03387142.1\| serine endoprotease [Salmonella enterica subsp. enterica serovar Typ... gi\|16504411, gi\|... - gi\|25305547\|pir\|\|AB0909 serine protease (EC 3.4.21.-) [imported] - Salmonella enterica subsp. enteri... gi\|29139232, gi\|... - gi\|29143597\|ref\|NP_806939.1\| serine endoprotease [Salmonella enterica subsp. enterica serovar Typhi ... gi\|213052237 - gi\|213052237\|ref\|ZP_03345115.1\| serine endoprotease [Salmonella enterica subsp. enterica serovar Typ... gi\|213424379 - gi\|213424379\|ref\|ZP_03357202.1\| serine endoprotease [Salmonella enterica subsp. enterica serovar Typ... gi\|213580506 - gi\|213580506\|ref\|ZP_03362332.1\| serine endoprotease [Salmonella enterica subsp. enterica serovar Typ... gi\|213609411 - gi\|213609411\|ref\|ZP_03369237.1\| serine endoprotease [Salmonella enterica subsp. enterica serovar Typ... gi\|56129533, gi\|... - gi\|56415276\|ref\|YP_152351.1\| serine endoprotease [Salmonella enterica subsp. enterica serovar Paraty... gi\|197364206, gi... - gi\|197364206\|ref\|YP_002143843.1\| serine endoprotease [Salmonella enterica subsp. enterica serovar Pa...	281.0	[0..1]	[355..1]
gi\|85721301, gi\|... - gi\|85858210\|ref\|YP_460412.1\| trypsin-like serine protease [Syntrophus aciditrophicus SB], gi\|8572130...	281.0	[0..3]	[353..10]

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Predicted Domain #1

Region A:
Residues: [1-355]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFVKLLRSVA IGLIVGAILL VAMPSLRSLN PLSTPQFDST DETPASYNLA VRRAAPAVVN  60
   61 VYNRGLNTNS HNQLEIRTLG SGVIMDQRGY IITNKHVIND ADQIIVALQD GRVFEALLVG 120
  121 SDSLTDLAVL KINATGGLPT IPINARRVPH IGDVVLAIGN PYNLGQTITQ GIISATGRIG 180
  181 LNPTGRQNFL QTDASINHGN SGGALVNSLG ELMGINTLSF DKSNDGETPE GIGFAIPFQL 240
  241 ATKIMDKLIR DGRVIRGYIG IGGREIAPLH AQGGGIDQLQ GIVVNEVSPD GPAANAGIQV 300
  301 NDLIISVDNK PAISALETMD QVAEIRPGSV IPVVVMRDDK QLTLQVTIQE YPATN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	66.0
Match:	1sozA
Description:	Crystal Structure of DegS protease in complex with an activating peptide
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits