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View Structure Prediction Details

Protein: DEGP1_ARATH
Organism: Arabidopsis thaliana
Length: 439 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DEGP1_ARATH.

Description E-value Query
Range
Subject
Range
gi|2565436 - gi|2565436|gb|AAC39436.1| DegP protease precursor [Arabidopsis thaliana]
315.0 [0..1] [439..1]

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Predicted Domain #1
Region A:
Residues: [1-103]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATTTSCSLL LSSTLFLHSP PSSHLSFFNL SSSRSSPISL YPIRSKRYFR ILSKLSLNDN  60
   61 NRDDDDDTLH FTPFSAVKPF FLLCTSVALS FSLFAASPAV ESA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [104-439]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SAFVVSTPKK LQTDELATVR LFQENTPSVV YITNLAVRQD AFTLDVLEVP QGSGSGFVWD  60
   61 KQGHIVTNYH VIRGASDLRV TLADQTTFDA KVVGFDQDKD VAVLRIDAPK NKLRPIPVGV 120
  121 SADLLVGQKV FAIGNPFGLD HTLTTGVISG LRREISSAAT GRPIQDVIQT DAAINPGNSG 180
  181 GPLLDSSGTL IGINTAIYSP SGASSGVGFS IPVDTVGGIV DQLVRFGKVT RPILGIKFAP 240
  241 DQSVEQLGVS GVLVLDAPPS GPAGKAGLQS TKRDGYGRLV LGDIITSVNG TKVSNGSDLY 300
  301 RILDQCKVGD EVTVEVLRGD HKEKISVTLE PKPDES

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 67.045757
Match: 1ky9A
Description: Protease Do (DegP, HtrA), C-terminal domains; Protease Do (DegP, HtrA), catalytic domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 4.45528883298499 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 4.08053412162226 bayes_pls_golite062009
endopeptidase activity 3.78841204092284 bayes_pls_golite062009
serine-type peptidase activity 3.58347664461084 bayes_pls_golite062009
serine hydrolase activity 3.58106288341801 bayes_pls_golite062009
serine-type endopeptidase activity 3.36658782366155 bayes_pls_golite062009
hydrolase activity 2.78416408149092 bayes_pls_golite062009
catalytic activity 1.40927913545237 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle