YRC Public Data Repository - Protein Structure Prediction

Protein:	DAPD_ECOLI
Organism:	Escherichia coli
Length:	274 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DAPD_ECOLI.

Description	E-value	Query Range	Subject Range
DAPD_SODGM - 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase OS=Sodalis glossinidius (strain m...	239.0	[0..1]	[274..1]
gi\|1574480 - gi\|1574480\|gb\|AAC23279.1\| 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase (dapD) [Hae... gi\|1075340 - gi\|1075340\|pir\|\|H64133 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase (EC 2.3.1....	238.0	[0..1]	[274..29]
gi\|145271550, gi... - gi\|145639247\|ref\|ZP_01794853.1\| 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase [Haem... gi\|145633035, gi... - gi\|145633035\|ref\|ZP_01788767.1\| 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase [Haem... gi\|46133365 - gi\|46133365\|ref\|ZP_00157070.2\| COG2171: Tetrahydrodipicolinate N-succinyltransferase [Haemophilus in...	237.0	[0..1]	[274..1]
DAPD_SHIDS - 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase OS=Shigella dysenteriae serotype ...	236.0	[0..1]	[274..1]
DAPD_PHOLL - 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase OS=Photorhabdus luminescens subsp... DAPD_PHOLL - 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase OS=Photorhabdus luminescens subsp...	236.0	[0..1]	[274..1]
gi\|145712 - gi\|145712\|gb\|AAA23667.1\| tetrahydrodipicolinate N-succinyltransferase (dapD)	236.0	[0..1]	[274..1]
DAPD_NITMU - 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase OS=Nitrosospira multiformis (stra...	236.0	[0..1]	[273..1]
gi\|68057975, gi\|... - gi\|68249776\|ref\|YP_248888.1\| 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [Hae...	235.0	[0..1]	[274..23]
gi\|145267689, gi... - gi\|145635081\|ref\|ZP_01790787.1\| phosphoenolpyruvate carboxylase [Haemophilus influenzae PittAA], gi\|... DAPD_HAEIN - 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase OS=Haemophilus influenzae (strain... gi\|53732876 - gi\|53732876\|ref\|ZP_00155204.2\| COG2171: Tetrahydrodipicolinate N-succinyltransferase [Haemophilus in... DAPD_HAEIN - 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase OS=Haemophilus influenzae GN=dapD... gi\|229811265, gi... - gi\|229846261\|ref\|ZP_04466373.1\| 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase [Haem... DAPD_HAEIE - 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase OS=Haemophilus influenzae (strain... gi\|145637521, gi... - gi\|145637521\|ref\|ZP_01793179.1\| 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase [Haem...	235.0	[0..1]	[274..1]
DAPD_ACTSZ - 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase OS=Actinobacillus succinogenes (s...	235.0	[0..1]	[274..1]

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Predicted Domain #1

Region A:
Residues: [1-274]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQQLQNIIET AFERRAEITP ANADTVTREA VNQVIALLDS GALRVAEKID GQWVTHQWLK  60
   61 KAVLLSFRIN DNQVIEGAES RYFDKVPMKF ADYDEARFQK EGFRVVPPAA VRQGAFIARN 120
  121 TVLMPSYVNI GAYVDEGTMV DTWATVGSCA QIGKNVHLSG GVGIGGVLEP LQANPTIIED 180
  181 NCFIGARSEV VEGVIVEEGS VISMGVYIGQ STRIYDRETG EIHYGRVPAG SVVVSGNLPS 240
  241 KDGKYSLYCA VIVKKVDAKT RGKVGINELL RTID

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	58.0
Match:	1kgqA
Description:	Tetrahydrodipicolinate-N-succinlytransferase, THDP-succinlytransferase, DapD
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.22811944286398	bayes_pls_golite062009
O-acyltransferase activity	1.64247384742412	bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups	1.61334532879528	bayes_pls_golite062009
acyltransferase activity	1.61097318205269	bayes_pls_golite062009
transferase activity, transferring acyl groups	1.61041958820284	bayes_pls_golite062009
transferase activity	1.1230560089123	bayes_pls_golite062009
O-acetyltransferase activity	0.289124788848623	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: