YRC Public Data Repository - Protein Structure Prediction

Protein:	CYSE_ECOLI
Organism:	Escherichia coli
Length:	273 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CYSE_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|82779100, gi\|... - gi\|82779100\|ref\|YP_405449.1\| serine acetyltransferase [Shigella dysenteriae Sd197], gi\|81243248\|gb\|A...	296.0	[0..1]	[273..1]
gi\|194420480, gi... - gi\|83571400\|ref\|ZP_00922840.1\| COG1045: Serine acetyltransferase [Shigella dysenteriae 1012], gi\|194...	295.0	[0..1]	[273..1]
gi\|197940671, gi... - gi\|198246155\|ref\|YP_002217661.1\| serine O-acetyltransferase [Salmonella enterica subsp. enterica ser... gi\|199604096, gi... - gi\|200386998\|ref\|ZP_03213610.1\| serine O-acetyltransferase [Salmonella enterica subsp. enterica sero... gi\|204928531, gi... - gi\|204928531\|ref\|ZP_03219730.1\| serine O-acetyltransferase [Salmonella enterica subsp. enterica sero... gi\|205354698, gi... - gi\|205354698\|ref\|YP_002228499.1\| serine acetyltransferase [Salmonella enterica subsp. enterica serov... gi\|205338723, gi... - gi\|205338723\|gb\|EDZ25487.1\| serine O-acetyltransferase [Salmonella enterica subsp. enterica serovar ... gi\|194406093, gi... - gi\|194447789\|ref\|YP_002047730.1\| serine acetyltransferase [Salmonella enterica subsp. enterica serov... gi\|194737807, gi... - gi\|194737807\|ref\|YP_002116634.1\| serine O-acetyltransferase [Salmonella enterica subsp. enterica ser... gi\|197215088, gi... - gi\|197251385\|ref\|YP_002148632.1\| serine acetyltransferase 4 [Salmonella enterica subsp. enterica ser... gi\|161366141, gi... - gi\|161616777\|ref\|YP_001590742.1\| serine acetyltransferase [Salmonella enterica subsp. enterica serov... gi\|168235303, gi... - gi\|197291620\|gb\|EDY30972.1\| serine O-acetyltransferase [Salmonella enterica subsp. enterica serovar ... gi\|29144100, gi\|... - gi\|29144100\|ref\|NP_807442.1\| serine acetyltransferase [Salmonella enterica subsp. enterica serovar T... gi\|16762611 - gi\|16762611\|ref\|NP_458228.1\| serine acetyltransferase [Salmonella enterica subsp. enterica serovar T... gi\|16504916, gi\|... - gi\|25286521\|pir\|\|AC0975 serine O-acetyltransferase (EC 2.3.1.30) - Salmonella enterica subsp. enteri... gi\|238910266 - gi\|238910266\|ref\|ZP_04654103.1\| serine acetyltransferase [Salmonella enterica subsp. enterica serova... gi\|213852186 - gi\|213852186\|ref\|ZP_03381718.1\| serine acetyltransferase [Salmonella enterica subsp. enterica serova... gi\|213999713 - gi\|213999713\|ref\|ZP_03410448.1\| serine acetyltransferase [Salmonella enterica subsp. enterica serova... gi\|206710739, gi... - gi\|207858936\|ref\|YP_002245587.1\| serine acetyltransferase [Salmonella enterica subsp. enterica serov... gi\|213163821 - gi\|213163821\|ref\|ZP_03349531.1\| serine acetyltransferase [Salmonella enterica subsp. enterica serova... gi\|213427156 - gi\|213427156\|ref\|ZP_03359906.1\| serine acetyltransferase [Salmonella enterica subsp. enterica serova... gi\|213647898 - gi\|213647898\|ref\|ZP_03377951.1\| serine acetyltransferase [Salmonella enterica subsp. enterica serova...	291.0	[0..1]	[273..1]
gi\|150957306, gi... - gi\|152972457\|ref\|YP_001337603.1\| serine acetyltransferase [Klebsiella pneumoniae subsp. pneumoniae M... gi\|110180259 - gi\|110180259\|gb\|ABG54369.1\| cysteine synthase [Klebsiella pneumoniae] gi\|206580507, gi... - gi\|206580507\|ref\|YP_002236028.1\| serine O-acetyltransferase [Klebsiella pneumoniae 342], gi\|20656956... gi\|238549379, gi... - gi\|238897051\|ref\|YP_002921797.1\| serine acetyltransferase [Klebsiella pneumoniae NTUH-K2044], gi\|238...	291.0	[0..1]	[273..1]
gi\|168464994, gi... - gi\|195632453\|gb\|EDX50937.1\| serine O-acetyltransferase [Salmonella enterica subsp. enterica serovar ... gi\|205344626, gi... - gi\|205344626\|gb\|EDZ31390.1\| serine O-acetyltransferase [Salmonella enterica subsp. enterica serovar ... gi\|194446045, gi... - gi\|194446045\|ref\|YP_002042949.1\| serine O-acetyltransferase [Salmonella enterica subsp. enterica ser... CYSE_SALTY - Serine acetyltransferase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=cysE PE=... gi\|194459030, gi... - gi\|194472666\|ref\|ZP_03078650.1\| serine O-acetyltransferase [Salmonella enterica subsp. enterica sero... gi\|205325766, gi... - gi\|205325766\|gb\|EDZ13605.1\| serine O-acetyltransferase [Salmonella enterica subsp. enterica serovar ... CYSE_SALTY - Serine acetyltransferase OS=Salmonella typhimurium GN=cysE PE=3 SV=1 gi\|167994319, gi... - gi\|205327791\|gb\|EDZ14555.1\| serine O-acetyltransferase [Salmonella enterica subsp. enterica serovar ... gi\|205333226, gi... - gi\|205333226\|gb\|EDZ19990.1\| serine O-acetyltransferase [Salmonella enterica subsp. enterica serovar ... gi\|205350520, gi... - gi\|205350520\|gb\|EDZ37151.1\| serine O-acetyltransferase [Salmonella enterica subsp. enterica serovar ... lcl\|NC_016856.1_... - [gene=cysE] [protein=serine acetyltransferase] [protein_id=YP_005239939.1] [location=complement(3907... gi\|62129825, gi\|... - gi\|62182192\|ref\|YP_218609.1\| serine acetyltransferase [Salmonella enterica subsp. enterica serovar C... CYSE_SALTY - Serine acetyltransferase OS=Salmonella typhimurium GN=cysE PE=3 SV=1 gi\|197265090, gi... - gi\|197265090\|ref\|ZP_03165164.1\| serine O-acetyltransferase [Salmonella enterica subsp. enterica sero...	291.0	[0..1]	[273..1]
gi\|197364516, gi... - gi\|197364516\|ref\|YP_002144153.1\| serine acetyltransferase [Salmonella enterica subsp. enterica serov... gi\|56415589, gi\|... - gi\|56415589\|ref\|YP_152664.1\| serine acetyltransferase [Salmonella enterica subsp. enterica serovar P...	290.0	[0..1]	[273..1]
gi\|77972956, gi\|... - gi\|77972956\|ref\|ZP_00828510.1\| COG1045: Serine acetyltransferase [Yersinia frederiksenii ATCC 33641]...	284.0	[0..1]	[273..29]
gi\|238798830, gi... - gi\|77961957\|ref\|ZP_00825784.1\| COG1045: Serine acetyltransferase [Yersinia mollaretii ATCC 43969], g...	283.0	[0..1]	[273..1]
gi\|238715078, gi... - gi\|77958479\|ref\|ZP_00822512.1\| COG1045: Serine acetyltransferase [Yersinia bercovieri ATCC 43970], g...	282.0	[0..1]	[273..1]
gi\|162420074, gi... - gi\|77634052\|ref\|ZP_00796161.1\| COG1045: Serine acetyltransferase [Yersinia pestis Angola], gi\|162420... gi\|77630854, gi\|... - gi\|77630854\|ref\|ZP_00793440.1\| COG1045: Serine acetyltransferase [Yersinia pseudotuberculosis IP 317... gi\|45434789, gi\|... - gi\|45439934\|ref\|NP_991473.1\| serine acetyltransferase [Yersinia pestis biovar Microtus str. 91001], ... gi\|165926110, gi... - gi\|165926110\|ref\|ZP_02221942.1\| serine O-acetyltransferase [Yersinia pestis biovar Orientalis str. F... gi\|167398569, gi... - gi\|167398569\|ref\|ZP_02304093.1\| serine O-acetyltransferase [Yersinia pestis biovar Antiqua str. UG05... gi\|167419406, gi... - gi\|167419406\|ref\|ZP_02311159.1\| serine O-acetyltransferase [Yersinia pestis biovar Orientalis str. M... gi\|167054355, gi... - gi\|167426666\|ref\|ZP_02318419.1\| serine O-acetyltransferase [Yersinia pestis biovar Mediaevalis str. ... gi\|22123993, gi\|... - gi\|22123993\|ref\|NP_667416.1\| serine acetyltransferase [Yersinia pestis KIM], gi\|21956734\|gb\|AAM83667... gi\|89103919 - gi\|89103919\|ref\|ZP_01176479.1\| COG1045: Serine acetyltransferase [Yersinia pestis biovar Orientalis ... gi\|186893411, gi... - gi\|186893411\|ref\|YP_001870523.1\| serine acetyltransferase [Yersinia pseudotuberculosis PB1/+], gi\|18...	282.0	[0..1]	[273..2]

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Predicted Domain #1

Region A:
Residues: [1-273]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSCEELEIVW NNIKAEARTL ADCEPMLASF YHATLLKHEN LGSALSYMLA NKLSSPIMPA  60
   61 IAIREVVEEA YAADPEMIAS AACDIQAVRT RDPAVDKYST PLLYLKGFHA LQAYRIGHWL 120
  121 WNQGRRALAI FLQNQVSVTF QVDIHPAAKI GRGIMLDHAT GIVVGETAVI ENDVSILQSV 180
  181 TLGGTGKSGG DRHPKIREGV MIGAGAKILG NIEVGRGAKI GAGSVVLQPV PPHTTAAGVP 240
  241 ARIVGKPDSD KPSMDMDQHF NGINHTFEYG DGI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	80.154902
Match:	1t3dA
Description:	Crystal structure of Serine Acetyltransferase from E.coli at 2.2A
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
serine O-acetyltransferase activity	7.87896510108566	bayes_pls_golite062009
serine O-acyltransferase activity	7.87896510108566	bayes_pls_golite062009
O-acyltransferase activity	3.5929335433661	bayes_pls_golite062009
O-acetyltransferase activity	2.49457770952472	bayes_pls_golite062009
catalytic activity	2.22811944286398	bayes_pls_golite062009
transferase activity	1.82656452828944	bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups	1.61334532879528	bayes_pls_golite062009
acyltransferase activity	1.61097318205269	bayes_pls_golite062009
transferase activity, transferring acyl groups	1.61041958820284	bayes_pls_golite062009
acetyltransferase activity	0.426204902618823	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: