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View Structure Prediction Details

Protein: Cpsf160-PA
Organism: Drosophila melanogaster
Length: 1455 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Cpsf160-PA.

Description E-value Query
Range
Subject
Range
CPSF1_MOUSE - Cleavage and polyadenylation specificity factor subunit 1 OS=Mus musculus GN=Cpsf1 PE=1 SV=1
1372.0 [0..1] [1455..1]

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Predicted Domain #1
Region A:
Residues: [1-186]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFSMCKQTHS ATAVEFSIAC RFFNNLDENL VVAGANVLKV YRIAPNVEAS QRQKLNPSEM  60
   61 RLAPKMRLEC LATYTLYGNV MSLQCVSLAG AMRDALLISF KDAKLSVLQH DPDTFALKTL 120
  121 SLHYFEEDDI RGGWTGRYFV PTVRVDPDSR CAVMLVYGKR LVVLPFRKDN SLDEIELADV 180
  181 KPIKKA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [187-236]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTAMVSRTPI MASYLIALRD LDEKIDNVLD IQFLHGYYEP TLLILYEPVR 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [237-364]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TCPGRIKVRS DTCVLVAISL NIQQRVHPII WTVNSLPFDC LQVYPIQKPI GGCLVMTVNA  60
   61 VIYLNQSVPP YGVSLNSSAD NSTAFPLKPQ DGVRISLDCA NFAFIDVDKL VISLRTGDLY 120
  121 VLTLCVDS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [365-473]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRTVRNFHFH KAAASVLTSC ICVLHSEYIF LGSRLGNSLL LHFTEEDQST VITLDEVEQQ  60
   61 SEQQQRNLQD EDQNLEEIFD VDQLEMAPTQ AKSRRIEDEE LEVYGSGAK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [474-744]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASVLQLRKFI FEVCDSLMNV APINYMCAGE RVEFEEDGVT LRPHAESLQD LKIELVAATG  60
   61 HSKNGALSVF VNCINPQIIT SFELDGCLDV WTVFDDATKK SSRNDQHDFM LLSQRNSTLV 120
  121 LQTGQEINEI ENTGFTVNQP TIFVGNLGQQ RFIVQVTTRH VRLLQGTRLI QNVPIDVGSP 180
  181 VVQVSIADPY VCLRVLNGQV ITLALRETRG TPRLAINKHT ISSSPAVVAI SAYKDLSGLF 240
  241 TVKGDDINLT GSSNSAFGHS FGGYMKAEPN M

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 44.0
Match: 2b5nA
Description: Crystal Structure of the DDB1 BPB Domain
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [745-1455]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KVEDEEDLLY GDAGSAFKMN SMADLAKQSK QKNSDWWRRL LVQAKPSYWL VVARQSGTLE  60
   61 IYSMPDMKLV YLVNDVGNGS MVLTDAMEFV PISLTTQENS KAGIVQACMP QHANSPLPLE 120
  121 LSVIGLGLNG ERPLLLVRTR VELLIYQVFR YPKGHLKIRF RKMDQLNLLD QQPTHIDLDE 180
  181 NDEQEEIESY QMQPKYVQKL RPFANVGGLS GVMVCGVNPC FVFLTFRGEL RIHRLLGNGD 240
  241 VRSFAAFNNV NIPNGFLYFD TTYELKISVL PSYLSYDSVW PVRKVPLRCT PRQLVYHREN 300
  301 RVYCLITQTE EPMTKYYRFN GEDKELSEES RGERFIYPIG SQFEMVLISP ETWEIVPDAS 360
  361 ITFEPWEHVT AFKIVKLSYE GTRSGLKEYL CIGTNFNYSE DITSRGNIHI YDIIEVVPEP 420
  421 GKPMTKFKIK EIFKKEQKGP VSAISDVLGF LVTGLGQKIY IWQLRDGDLI GVAFIDTNIY 480
  481 VHQIITVKSL IFIADVYKSI SLLRFQEEYR TLSLASRDFN PLEVYGIEFM VDNSNLGFLV 540
  541 TDAERNIIVY MYQPEARESL GGQKLLRKAD YHLGQVVNTM FRVQCHQKGL HQRQPFLYEN 600
  601 KHFVVYGTLD GALGYCLPLP EKVYRRFLML QNVLLSYQEH LCGLNPKEYR TLKSSKKQGI 660
  661 NPSRCIIDGD LIWSYRLMAN SERNEVAKKI GTRTEEILGD LLEIERLASV F

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 146.0
Match: 2b5lA
Description: Crystal Structure of DDB1 In Complex with Simian Virus 5 V Protein
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle