YRC Public Data Repository - Protein Structure Prediction

Protein:	COBS_ECOLI
Organism:	Escherichia coli
Length:	247 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COBS_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|90572875, gi\|... - gi\|90572875\|ref\|ZP_01229397.1\| hypothetical protein CdifQ_02003782 [Clostridium difficile QCD-32g58]...	215.0	[0..2]	[244..1]
COBS_VIBPA - Adenosylcobinamide-GDP ribazoletransferase OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 22... COBS_VIBPA - Cobalamin synthase OS=Vibrio parahaemolyticus GN=cobS PE=3 SV=1	208.0	[0..2]	[247..16]
gi\|90413241, gi\|... - gi\|90413241\|ref\|ZP_01221236.1\| cobalamin synthase [Photobacterium profundum 3TCK], gi\|90325793\|gb\|EA...	207.0	[0..5]	[247..32]
gi\|115513304, gi... - gi\|117624180\|ref\|YP_853093.1\| cobalamin synthase [Escherichia coli APEC O1], gi\|115513304\|gb\|ABJ0137...	205.0	[0..1]	[247..13]
gi\|26248330, gi\|... - gi\|26248330\|ref\|NP_754370.1\| cobalamin synthase [Escherichia coli CFT073], gi\|26108734\|gb\|AAN80937.1... gi\|91072817, gi\|... - gi\|91211243\|ref\|YP_541229.1\| cobalamin synthase [Escherichia coli UTI89], gi\|91072817\|gb\|ABE07698.1\|... gi\|226900774, gi... - gi\|237704408\|ref\|ZP_04534889.1\| cobalamin synthase [Escherichia sp. 3_2_53FAA], gi\|226900774\|gb\|EEH8...	205.0	[0..1]	[247..13]
gi\|151939183, gi... - gi\|75856576\|ref\|ZP_00764202.1\| COG0368: Cobalamin-5-phosphate synthase [Vibrio sp. Ex25], gi\|2542283...	205.0	[0..2]	[247..19]
gi\|89073413, gi\|... - gi\|89073413\|ref\|ZP_01159937.1\| cobalamin synthase [Photobacterium sp. SKA34], gi\|89050900\|gb\|EAR5637...	203.0	[0..2]	[247..22]
gi\|208739820, gi... - gi\|208819697\|ref\|ZP_03260017.1\| cobalamin 5'-phosphate synthase [Escherichia coli O157:H7 str. EC404... COBS_ECO5E - Adenosylcobinamide-GDP ribazoletransferase OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=cob... gi\|217317459, gi... - gi\|217329691\|ref\|ZP_03445770.1\| cobalamin 5'-phosphate synthase [Escherichia coli O157:H7 str. TW145... COBS_ECO57 - Adenosylcobinamide-GDP ribazoletransferase OS=Escherichia coli O157:H7 GN=cobS PE=3 SV=1 gi\|15832041, gi\|... - gi\|15832041\|ref\|NP_310814.1\| cobalamin synthase [Escherichia coli O157:H7 str. Sakai], gi\|13362255\|d... gi\|189360741, gi... - gi\|189360741\|gb\|EDU79160.1\| cobalamin 5'-phosphate synthase [Escherichia coli O157:H7 str. EC4486], ... gi\|168777132, gi... - gi\|187767610\|gb\|EDU31454.1\| cobalamin 5'-phosphate synthase [Escherichia coli O157:H7 str. EC4196], ... gi\|168784075, gi... - gi\|188998689\|gb\|EDU67675.1\| cobalamin 5'-phosphate synthase [Escherichia coli O157:H7 str. EC4076], ... gi\|168790187, gi... - gi\|189370304\|gb\|EDU88720.1\| cobalamin 5'-phosphate synthase [Escherichia coli O157:H7 str. EC869], g... gi\|168801986, gi... - gi\|189375956\|gb\|EDU94372.1\| cobalamin 5'-phosphate synthase [Escherichia coli O157:H7 str. EC508], g... gi\|195939500 - gi\|195939500\|ref\|ZP_03084882.1\| cobalamin synthase [Escherichia coli O157:H7 str. EC4024] gi\|208724978, gi... - gi\|208810462\|ref\|ZP_03252338.1\| cobalamin 5'-phosphate synthase [Escherichia coli O157:H7 str. EC420... gi\|208731045, gi... - gi\|208816702\|ref\|ZP_03257822.1\| cobalamin 5'-phosphate synthase [Escherichia coli O157:H7 str. EC404... gi\|254593094, gi... - gi\|254793694\|ref\|YP_003078531.1\| cobalamin 5'-phosphate synthase [Escherichia coli O157:H7 str. TW14... gi\|188014419, gi... - gi\|188014419\|gb\|EDU52541.1\| cobalamin 5'-phosphate synthase [Escherichia coli O157:H7 str. EC4113], ... gi\|168758419, gi... - gi\|189354731\|gb\|EDU73150.1\| cobalamin 5'-phosphate synthase [Escherichia coli O157:H7 str. EC4401], ... gi\|168764068, gi... - gi\|189365867\|gb\|EDU84283.1\| cobalamin 5'-phosphate synthase [Escherichia coli O157:H7 str. EC4501], ... gi\|209748318, gi... - pir\|\|A85824 cobalamin 5'-phosphate synthase [imported] - Escherichia coli (strain O157:H7, substrain... gi\|75259127, gi\|... - gi\|75259127\|ref\|ZP_00730475.1\| COG0368: Cobalamin-5-phosphate synthase [Escherichia coli E22], gi\|19... gi\|12516169, gi\|... - gi\|15802473\|ref\|NP_288499.1\| cobalamin synthase [Escherichia coli O157:H7 EDL933], gi\|12516169\|gb\|AA...	201.0	[0..1]	[247..1]
gi\|191169928, gi... - gi\|75242806\|ref\|ZP_00726512.1\| COG0368: Cobalamin-5-phosphate synthase [Escherichia coli F11], gi\|19... COBS_ECO7I - Adenosylcobinamide-GDP ribazoletransferase OS=Escherichia coli O7:K1 (strain IAI39 / ExPEC) GN=cobS ... COBS_ECOL6 - Cobalamin synthase OS=Escherichia coli O6 GN=cobS PE=3 SV=2 COBS_ECOL6 - Adenosylcobinamide-GDP ribazoletransferase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / ... gi\|227885539, gi... - gi\|227885539\|ref\|ZP_04003344.1\| cobalamin synthase [Escherichia coli 83972], gi\|227837479\|gb\|EEJ4794... COBS_ECOL5 - Adenosylcobinamide-GDP ribazoletransferase OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=cob...	201.0	[0..1]	[247..1]
gi\|192955063, gi... - gi\|75214803\|ref\|ZP_00713292.1\| COG0368: Cobalamin-5-phosphate synthase [Escherichia coli E110019], g... gi\|75210052, gi\|... - gi\|75210052\|ref\|ZP_00710235.1\| COG0368: Cobalamin-5-phosphate synthase [Escherichia coli B171], gi\|1... COBS_ECOHS - Adenosylcobinamide-GDP ribazoletransferase OS=Escherichia coli O9:H4 (strain HS) GN=cobS PE=3 SV=1 COBS_ECO24 - Adenosylcobinamide-GDP ribazoletransferase OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=c... COBS_SHISS - Adenosylcobinamide-GDP ribazoletransferase OS=Shigella sonnei (strain Ss046) GN=cobS PE=3 SV=1 gi\|75514016, gi\|... - gi\|75514016\|ref\|ZP_00736346.1\| COG0368: Cobalamin-5-phosphate synthase [Escherichia coli 53638], gi\|... gi\|75229133, gi\|... - gi\|75229133\|ref\|ZP_00715708.1\| COG0368: Cobalamin-5-phosphate synthase [Escherichia coli B7A], gi\|19... COBS_ECO8A - Adenosylcobinamide-GDP ribazoletransferase OS=Escherichia coli O8 (strain IAI1) GN=cobS PE=3 SV=1 COBS_ECO55 - Adenosylcobinamide-GDP ribazoletransferase OS=Escherichia coli (strain 55989 / EAEC) GN=cobS PE=3 SV... COBS_ECOSM - Adenosylcobinamide-GDP ribazoletransferase OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=cobS PE=3... COBS_ECOSE - Adenosylcobinamide-GDP ribazoletransferase OS=Escherichia coli (strain SE11) GN=cobS PE=3 SV=1 COBS_SHIB3 - Adenosylcobinamide-GDP ribazoletransferase OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS51... gi\|194435976, gi... - gi\|83587996\|ref\|ZP_00926621.1\| COG0368: Cobalamin-5-phosphate synthase [Escherichia coli 101-1], gi\|...	201.0	[0..1]	[247..1]

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Predicted Domain #1

Region A:
Residues: [1-247]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKLFWAMLS FITRLPVPRR WSQGLDFEHY SRGIITFPLI GLLLGAISGL VFMVLQAWCG  60
   61 APLAALFSVL VLVLMTGGFH LDGLADTCDG VFSARSRDRM LEIMRDSRLG THGGLALIFV 120
  121 VLAKILVLSE LALRGESILA SLAAACAVSR GTAALLMYRH RYAREEGLGN VFIGKIDGRQ 180
  181 TCVTLGLAAI FAAVLLPGMH GVAAMVVTMV AIFILGQLLK RTLGGQTGDT LGAAIELGEL 240
  241 VFLLALL

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits