YRC Public Data Repository - Protein Structure Prediction

Protein:	BIOH_ECOLI
Organism:	Escherichia coli
Length:	256 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BIOH_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|71555648, gi\|... - gi\|71735095\|ref\|YP_276638.1\| arylesterase [Pseudomonas syringae pv. phaseolicola 1448A], gi\|71555648...	195.0	[0..2]	[254..97]
tr\|Q889S4\|Q889S4... - Arylesterase OS=Pseudomonas syringae pv. tomato (strain DC3000) GN=PSPTO_0675 PE=4 SV=1 gi\|28867903, gi\|... - gi\|28867903\|ref\|NP_790522.1\| arylesterase [Pseudomonas syringae pv. tomato str. DC3000], gi\|28851139...	192.0	[0..2]	[255..10]
gi\|78066438, gi\|... - gi\|78066438\|ref\|YP_369207.1\| Alpha/beta hydrolase [Burkholderia sp. 383], gi\|77967183\|gb\|ABB08563.1\|...	192.0	[0..2]	[254..10]
gi\|63258412, gi\|... - gi\|66047705\|ref\|YP_237546.1\| Alpha/beta hydrolase fold [Pseudomonas syringae pv. syringae B728a], gi...	192.0	[0..2]	[254..10]
gi\|77383490, gi\|... - gi\|77459487\|ref\|YP_348994.1\| Alpha/beta hydrolase fold [Pseudomonas fluorescens Pf0-1], gi\|77383490\|...	190.0	[0..2]	[255..10]
gi\|68529012, gi\|... - gi\|94314231\|ref\|YP_587440.1\| alpha/beta hydrolase fold [Ralstonia metallidurans CH34], gi\|93358083\|g...	189.0	[0..2]	[254..10]
gi\|50513956, gi\|... - gi\|50513956\|pdb\|1VA4\|F Chain F, Pseudomonas Fluorescens Aryl Esterase, gi\|50513955\|pdb\|1VA4\|E Chain ...	187.0	[0..2]	[255..9]
gi\|73539032, gi\|... - gi\|73539032\|ref\|YP_299399.1\| Alpha/beta hydrolase fold [Ralstonia eutropha JMP134], gi\|72122369\|gb\|A...	187.0	[0..2]	[255..10]
gi\|91690961, gi\|... - gi\|91778301\|ref\|YP_553509.1\| non-heme chloroperoxidase [Burkholderia xenovorans LB400], gi\|91690961\|...	187.0	[0..2]	[255..10]
gi\|95113282 - gi\|95113282\|emb\|CAK18010.1\| putative hydrolase, alpha/beta fold family [Pseudomonas entomophila L48] gi\|95113282, gi\|... - gi\|95113282\|emb\|CAK18010.1\| putative hydrolase, alpha/beta fold family [Pseudomonas entomophila L48]...	187.0	[0..2]	[255..10]

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Predicted Domain #1

Region A:
Residues: [1-256]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNNIWWQTKG QGNVHLVLLH GWGLNAEVWR CIDEELSSHF TLHLVDLPGF GRSRGFGALS  60
   61 LADMAEAVLQ QAPDKAIWLG WSLGGLVASQ IALTHPERVQ ALVTVASSPC FSARDEWPGI 120
  121 KPDVLAGFQQ QLSDDFQRTV ERFLALQTMG TETARQDARA LKKTVLALPM PEVDVLNGGL 180
  181 EILKTVDLRQ PLQNVSMPFL RLYGYLDGLV PRKVVPMLDK LWPHSESYIF AKAAHAPFIS 240
  241 HPAEFCHLLV ALKQRV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	42.69897
Match:	1m33A
Description:	Biotin biosynthesis protein BioH
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.76673721118052	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.0940814269146387	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: