YRC Public Data Repository - Protein Structure Prediction

Protein:	BGA2_ECOLI
Organism:	Escherichia coli
Length:	1030 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BGA2_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|81246742, gi\|... - gi\|82545331\|ref\|YP_409278.1\| evolved beta-D-galactosidase, alpha subunit [Shigella boydii Sb227], gi...	1094.0	[0..1]	[1030..13]
gi\|218353512, gi... - gi\|218696780\|ref\|YP_002404447.1\| cryptic beta-D-galactosidase subunit alpha [Escherichia coli 55989]... gi\|209913807, gi... - gi\|209920548\|ref\|YP_002294632.1\| cryptic beta-D-galactosidase subunit alpha [Escherichia coli SE11],... gi\|75260008, gi\|... - gi\|75260008\|ref\|ZP_00731286.1\| COG3250: Beta-galactosidase/beta-glucuronidase [Escherichia coli E22]... gi\|75211029, gi\|... - gi\|75211029\|ref\|ZP_00711142.1\| COG3250: Beta-galactosidase/beta-glucuronidase [Escherichia coli B171...	1093.0	[0..1]	[1030..1]
gi\|7428188, gi\|6... - pir\|\|GBECE beta-galactosidase (EC 3.2.1.23) alpha chain - Escherichia coli (strain K-12), gi\|606014\|... gi\|606014\|gb\|AAA... - phospho-beta-D-galactosidase; alpha-subunit [Escherichia coli]	1093.0	[0..1]	[1030..13]
gi\|191172186, gi... - gi\|75240893\|ref\|ZP_00724791.1\| COG3250: Beta-galactosidase/beta-glucuronidase [Escherichia coli F11]...	1093.0	[0..1]	[1030..1]
gi\|91212507, gi\|... - gi\|91212507\|ref\|YP_542493.1\| cryptic beta-D-galactosidase subunit alpha [Escherichia coli UTI89], gi... gi\|226899201, gi... - gi\|237706161\|ref\|ZP_04536642.1\| evolved beta-galactosidase alpha-subunit [Escherichia sp. 3_2_53FAA]...	1092.0	[0..1]	[1030..60]
gi\|191166865, gi... - gi\|75230007\|ref\|ZP_00716520.1\| COG3250: Beta-galactosidase/beta-glucuronidase [Escherichia coli B7A]...	1092.0	[0..1]	[1030..1]
gi\|157080569, gi... - gi\|75187885\|ref\|ZP_00701152.1\| COG3250: Beta-galactosidase/beta-glucuronidase [Escherichia coli E243...	1092.0	[0..1]	[1030..1]
gi\|192959294, gi... - gi\|75239354\|ref\|ZP_00723325.1\| COG3250: Beta-galactosidase/beta-glucuronidase [Escherichia coli E110...	1092.0	[0..1]	[1030..1]
gi\|188495475, gi... - gi\|75513289\|ref\|ZP_00735713.1\| COG3250: Beta-galactosidase/beta-glucuronidase [Escherichia coli 5363...	1091.0	[0..1]	[1030..1]
gi\|15803617, gi\|... - gi\|15803617\|ref\|NP_289650.1\| evolved beta-D-galactosidase, alpha subunit; cryptic gene [Escherichia ... gi\|13363431 - gi\|13363431\|dbj\|BAB37381.1\| evolved beta-D-galactosidase alpha subunit [Escherichia coli O157:H7] gi\|13363431 - gi\|13363431\|dbj\|BAB37381.1\| evolved beta-D-galactosidase alpha subunit [Escherichia coli O157:H7 str... gi\|25289535, gi\|... - pir\|\|E85968 evolved beta-D-galactosidase alpha subunit [imported] - Escherichia coli (strain O157:H7...	1091.0	[0..1]	[1030..13]

Back

Predicted Domain #1

Region A:
Residues: [1-1030]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNRWENIQLT HENRLAPRAY FFSYDSVAQA RTFARETSSL FLPLSGQWNF HFFDHPLQVP  60
   61 EAFTSELMAD WGHITVPAMW QMEGHGKLQY TDEGFPFPID VPFVPSDNPT GAYQRIFTLS 120
  121 DGWQGKQTLI KFDGVETYFE VYVNGQYVGF SKGSRLTAEF DISAMVKTGD NLLCVRVMQW 180
  181 ADSTYVEDQD MWWSAGIFRD VYLVGKHLTH INDFTVRTDF DEAYCDATLS CEVVLENLAA 240
  241 SPVVTTLEYT LFDGERVVHS SAIDHLAIEK LTSASFAFTV EQPQQWSAES PYLYHLVMTL 300
  301 KDANGNVLEV VPQRVGFRDI KVRDGLFWIN NRYVMLHGVN RHDNDHRKGR AVGMDRVEKD 360
  361 LQLMKQHNIN SVRTAHYPND PRFYELCDIY GLFVMAETDV ESHGFANVGD ISRITDDPQW 420
  421 EKVYVERIVR HIHAQKNHPS IIIWSLGNES GYGCNIRAMY HAAKALDDTR LVHYEEDRDA 480
  481 EVVDIISTMY TRVPLMNEFG EYPHPKPRII CEYAHAMGNG PGGLTEYQNV FYKHDCIQGH 540
  541 YVWEWCDHGI QAQDDHGNVW YKFGGDYGDY PNNYNFCLDG LIYSDQTPGP GLKEYKQVIA 600
  601 PVKIHARDLT RGELKVENKL WFTTLDDYTL HAEVRAEGET LATQQIKLRD VAPNSEAPLQ 660
  661 ITLPQLDARE AFLNITVTKD SRTRYSEAGH PIATYQFPLK ENTAQPVPFA PNNARPLTLE 720
  721 DDRLSCTVRG YNFAITFSKM SGKPTSWQVN GESLLTREPK INFFKPMIDN HKQEYEGLWQ 780
  781 PNHLQIMQEH LRDFAVEQSD GEVLIISRTV IAPPVFDFGM RCTYIWRIAA DGQVNVALSG 840
  841 ERYGDYPHII PCIGFTMGIN GEYDQVAYYG RGPGENYADS QQANIIDIWR STVDAMFENY 900
  901 PFPQNNGNRQ HVRWTALTNR HGNGLLVVPQ RPINFSAWHY TQENIHAAQH CNELQRSDDI 960
  961 TLNLDHQLLG LGSNSWGSEV LDSWRVWFRD FSYGFTLLPV SGGEATAQSL ASYEFGAGFF1020
 1021 STNLHSENKQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	1bglA
Description:	beta-Galactosidase, domains 2 and 4; beta-Galactosidase; beta-Galactosidase, domain 5; beta-Galactosidase, domain 3
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
alpha,alpha-phosphotrehalase activity	1.21971230909808	bayes_pls_golite062009
racemase and epimerase activity, acting on carbohydrates and derivatives	1.21567860634685	bayes_pls_golite062009
racemase and epimerase activity	1.19295069153058	bayes_pls_golite062009
catalytic activity	1.14137378674629	bayes_pls_golite062009
trehalase activity	0.8585169360333	bayes_pls_golite062009
sucrose phosphorylase activity	0.67048515776965	bayes_pls_golite062009
isomerase activity	0.62004466537384	bayes_pls_golite062009
glucosidase activity	0.58717079348538	bayes_pls_golite062009
hexosaminidase activity	0.16438321606077	bayes_pls_golite062009
amylase activity	0.0914002140078796	bayes_pls_golite062009
alpha-amylase activity	0.0521244165288097	bayes_pls_golite062009
chitinase activity	0.0382131529139698	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: