YRC Public Data Repository - Protein Structure Prediction

Protein:	BCP_ECOLI
Organism:	Escherichia coli
Length:	156 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BCP_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|56419012, gi\|... - gi\|56419012\|ref\|YP_146330.1\| bacterioferritin comigratory protein [Geobacillus kaustophilus HTA426],...	174.0	[0..3]	[156..2]
gi\|55772682, gi\|... - gi\|55981269\|ref\|YP_144566.1\| bacterioferritin comigratory protein, thiol peroxidase, putative [Therm...	172.0	[0..1]	[155..1]
gi\|46196862, gi\|... - gi\|46199237\|ref\|YP_004904.1\| bacterioferritin comigratory protein [Thermus thermophilus HB27], gi\|46...	172.0	[0..1]	[155..1]
gi\|86608016 - gi\|86608016\|ref\|YP_476778.1\| bacterioferritin comigratory protein [Cyanobacteria bacterium Yellowsto... gi\|86608016, gi\|... - gi\|86608016\|ref\|YP_476778.1\| bacterioferritin comigratory protein [Synechococcus sp. JA-2-3B'a(2-13)...	172.0	[0..3]	[152..2]
gi\|166854732, gi... - gi\|167040492\|ref\|YP_001663477.1\| alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal alle...	171.0	[0..2]	[155..24]
gi\|76587267, gi\|... - gi\|76797358\|ref\|ZP_00779683.1\| Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allerg...	171.0	[0..2]	[155..24]
gi\|86606785 - gi\|86606785\|ref\|YP_475548.1\| bacterioferritin comigratory protein [Cyanobacteria bacterium Yellowsto... gi\|86555327, gi\|... - gi\|86606785\|ref\|YP_475548.1\| bacterioferritin comigratory protein [Synechococcus sp. JA-3-3Ab], gi\|8...	169.0	[0..1]	[152..1]
gi\|25319019 - pir\|\|AH2118 bacterioferritin comigratory protein [imported] - Nostoc sp. (strain PCC 7120) gi\|17229995, gi\|... - gi\|17229995\|ref\|NP_486543.1\| bacterioferritin comigratory protein [Nostoc sp. PCC 7120], gi\|17131595...	167.0	[0..2]	[155..3]
gi\|23126611, gi\|... - gi\|23126611\|ref\|ZP_00108501.1\| COG1225: Peroxiredoxin [Nostoc punctiforme PCC 73102], gi\|186686487\|r...	167.0	[0..2]	[156..3]
gi\|25319001 - pir\|\|D83768 bacterioferritin comigratory protein BH0948 [imported] - Bacillus halodurans (strain C-1... gi\|10173563, gi\|... - gi\|15613511\|ref\|NP_241814.1\| bacterioferritin comigratory protein [Bacillus halodurans C-125], gi\|10...	167.0	[0..4]	[154..1]

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Predicted Domain #1

Region A:
Residues: [1-156]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNPLKAGDIA PKFSLPDQDG EQVNLTDFQG QRVLVYFYPK AMTPGCTVQA CGLRDNMDEL  60
   61 KKAGVDVLGI STDKPEKLSR FAEKELLNFT LLSDEDHQVC EQFGVWGEKS FMGKTYDGIH 120
  121 RISFLIDADG KIEHVFDDFK TSNHHDVVLN WLKEHA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	36.0
Match:	1qmvA
Description:	Thioredoxin peroxidase 2 (thioredoxin peroxidase B, 2-cys peroxiredoxin)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
antioxidant activity	2.76704361987669	bayes_pls_golite062009
peroxidase activity	2.4535286431475	bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor	2.4535286431475	bayes_pls_golite062009
peroxiredoxin activity	1.60801416784303	bayes_pls_golite062009
thioredoxin peroxidase activity	1.48148817403114	bayes_pls_golite062009
glutathione peroxidase activity	1.40767929314355	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	1.17905334170166	bayes_pls_golite062009
disulfide oxidoreductase activity	0.691543699484554	bayes_pls_golite062009
catalytic activity	0.672192331361968	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: