YRC Public Data Repository - Protein Structure Prediction

Protein:	AROL_ECOLI
Organism:	Escherichia coli
Length:	174 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AROL_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|77634951 - gi\|77634951\|ref\|ZP_00797042.1\| COG0703: Shikimate kinase [Yersinia pestis Angola] gi\|89105974 - gi\|89105974\|ref\|ZP_01178485.1\| COG0703: Shikimate kinase [Yersinia pestis biovar Orientalis str. IP2...	150.0	[0..1]	[168..41]
gi\|77631881, gi\|... - gi\|77631881\|ref\|ZP_00794467.1\| COG0703: Shikimate kinase [Yersinia pseudotuberculosis IP 31758], gi\|...	150.0	[0..1]	[168..41]
AROL_SHIFL - Shikimate kinase 2 OS=Shigella flexneri GN=aroL PE=3 SV=6 gi\|30061884, gi\|... - gi\|30061884\|ref\|NP_836055.1\| shikimate kinase II [Shigella flexneri 2a str. 2457T], gi\|30040128\|gb\|A... gi\|56383195, gi\|... - gi\|56479644\|ref\|NP_706276.2\| shikimate kinase II [Shigella flexneri 2a str. 301], gi\|56383195\|gb\|AAN... AROL_SHIB3 - Shikimate kinase 2 OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=aroL PE=3 SV=1	150.0	[0..1]	[174..1]
gi\|77974353, gi\|... - gi\|77974353\|ref\|ZP_00829894.1\| COG0703: Shikimate kinase [Yersinia frederiksenii ATCC 33641], gi\|238...	149.0	[0..1]	[168..1]
gi\|191639450, gi... - gi\|191639450\|ref\|YP_001988616.1\| ATP-dependent zinc metalloendopeptidase FtsH (Cell division protein... gi\|239630370, gi... - gi\|239630370\|ref\|ZP_04673401.1\| ATP-dependent Zn protease [Lactobacillus paracasei subsp. paracasei ... gi\|116495971, gi... - gi\|116495971\|ref\|YP_807705.1\| ATP-dependent Zn protease [Lactobacillus casei ATCC 334], gi\|116106121...	149.0	[0..1]	[170..221]
AROL_SHIDS - Shikimate kinase 2 OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=aroL PE=3 SV=3	148.0	[0..1]	[174..1]
gi\|77978390 - gi\|77978390\|ref\|ZP_00833820.1\| COG0703: Shikimate kinase [Yersinia intermedia ATCC 29909]	148.0	[0..1]	[168..1]
gi\|119025427, gi... - gi\|119025427\|ref\|YP_909272.1\| hypothetical protein BAD_0409 [Bifidobacterium adolescentis ATCC 15703... gi\|85666505 - gi\|85666505\|ref\|ZP_01028729.1\| hypothetical protein Badol_01001350 [Bifidobacterium adolescentis]	148.0	[0..1]	[170..255]
gi\|52857918 - gi\|52857918\|ref\|ZP_00047019.2\| COG0465: ATP-dependent Zn proteases [Lactobacillus gasseri] gi\|52857918 - gi\|52857918\|ref\|ZP_00047019.2\| hypothetical protein Lgas_03001412 [Lactobacillus gasseri ATCC 33323]	147.0	[0..1]	[170..205]
gi\|41582654, gi\|... - gi\|42518369\|ref\|NP_964299.1\| cell division protein FtsH-like protein [Lactobacillus johnsonii NCC 53...	147.0	[0..1]	[170..224]

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Predicted Domain #1

Region A:
Residues: [1-174]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTQPLFLIGP RGCGKTTVGM ALADSLNRRF VDTDQWLQSQ LNMTVAEIVE REEWAGFRAR  60
   61 ETAALEAVTA PSTVIATGGG IILTEFNRHF MQNNGIVVYL CAPVSVLVNR LQAAPEEDLR 120
  121 PTLTGKPLSE EVQEVLEERD ALYREVAHII IDATNEPSQV ISEIRSALAQ TINC

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	34.0
Match:	1shkA
Description:	Shikimate kinase (AroK)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.37148167194523	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: